Abstract
There are a number of translation inhibitors whose site of action is not yet well known. Thus the antibacterial antibiotic avilamycin blocks protein synthesis in intact bacteria and bacterial cell-free systems (Wolf, 1973). The effect of the antibiotic is located on the 30S ribosomal subunit and inhibits polynucleotide-directed binding of f-Met-tRNA and Phe-tRNA to the ribosome. Since the antibiotic has not been studied in more resolved systems it is not known whether it can be considered an inhibitor of step (d) or of initiation.
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© 1979 Springer-Verlag Berlin · Heidelberg
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Vázquez, D. (1979). Miscellaneous Inhibitors of Translation. In: Inhibitors of Protein Biosynthesis. Molecular Biology Biochemistry and Biophysics, vol 30. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81309-2_5
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DOI: https://doi.org/10.1007/978-3-642-81309-2_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81311-5
Online ISBN: 978-3-642-81309-2
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