Postnatal Development of the Cat’s Retina: A Concept of Maturation Obtained by Qualitative and Quantitative Examinations

  • Margarete Vogel
Conference paper
Part of the Current Research in Ophthalmic Electron Microscopy book series (CR OPHTHALMIC, volume 2)


From a coherent morphological and morphometrical investigation of the postnatal development of the cat’s retina, some main aspects are presented concerning the structures lying outside the outer limiting membrane, the neuropile layers and the nuclear layers. It is shown by means of qualitative and quantitative results, that the maturation process of the various cellular elements in the cat’s retina can be devided into three phases and is presumably finished between the 4th to the 5th month of life.


Outer Segment Plexiform Layer Outer Nuclear Layer Outer Plexiform Layer Postnatal Development 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Anderson, D.H., Fisher, S.K.: The photoreceptors of diurnal squirrels: outer segment structure, disc shedding and protein renewal. J. Ultrastruct. Res. 55, 119–141 (1976)PubMedCrossRefGoogle Scholar
  2. Arey, L.B.: Retina, chorioid and sclera. In: Cytology and Cellular Pathology of the Nervous System. Penfield, W., New York, Hafner Publishing Comp., 1965 (originally published 1932 by P.B. Hoeber, Inc., New York, reprinted 1965, without change by arrangement) Vol. II, pp. 769–770Google Scholar
  3. Babuchin, Beitraege zur Entwicklungsgeschichte des Auges, besonders der Retina. Würzburger Naturwiss. Z. Bd. IV, 71–90 (1863)Google Scholar
  4. Blanks, J.C., Adinolfl, A.M., Lolley, R.N.: Synaptogenesis in the photoreceptor terminal of the mouse retina. J. Comp. Neurol. 156, 81–93 (1974)PubMedCrossRefGoogle Scholar
  5. Cajal, S.R.: La rétine des vertébrés. Cellule 9, 191–256 (1893)Google Scholar
  6. Cajal, S.R.: Die Retina der Wirbelthiere. (übers, v. Greef, R.), Wiesbaden, J.F. Bergmann-Verlag, 1894Google Scholar
  7. Cohen, A.J.: The ultrastructure of the rods of the mouse retina. Am. J. Anat. 107, 23–48 (1960)PubMedCrossRefGoogle Scholar
  8. Cragg, B.G.: The development of synapses in the visual system of the cat. J. Comp. Neurol. 160, 147–166 (1975)PubMedCrossRefGoogle Scholar
  9. De Robertis, E.: Some observations on the ultrastructure and morphogenesis of photoreceptors. J. Gen. Physiol. 43, 1–13 (1960)CrossRefGoogle Scholar
  10. Donovan, A.: The postnatal development of the cat’s retina. Exp. Eye Res. 5, 249–254 (1966)PubMedCrossRefGoogle Scholar
  11. Fürst, C.M.: Zur Kenntnis der Histogenese und des Wachstums der Retina. Acta Univ. Lund 40, 1–46 (1904)Google Scholar
  12. Glücksman, A.: Development and differentiation of the tadpole eye. Br. J. Ophthal. 24, 153–178 (1940)CrossRefGoogle Scholar
  13. Haug, H.: Die Treffermethode, ein Verfahren zur quantitativen Analyse im histologischen Schnitt. Z. Anat. Entwickl.-Gesch. 118, 302–312 (1955)CrossRefGoogle Scholar
  14. Haug, H.: Die Treffermethode, ein Verfahren zur quantitativen Analyse im histologischen Schnitt. Z. Anat. Entwickl.-Gesch. 118, 302–312 (1955)CrossRefGoogle Scholar
  15. Haug, H.: Bedeutung und Grenzen der quantitativen Meßmethoden in der Histologie. In: Medizinische Grundlagenforschung, Bauer, K.F., Bd. IV, S. 302–342. Stuttgart: Thieme 1962Google Scholar
  16. Haug, H.: Die Membrana limitans gliae superficialis der Sehrinde der Katze. Z. Zellforsch. 115, 79–87 (1971)PubMedCrossRefGoogle Scholar
  17. Hebel, R.: Entwicklung und Struktur der Retina und des Tapetum lucidum des Hundes. Ergebn. Anat. Entwickl.-Gesch. 45, 1–93 (1971)Google Scholar
  18. Hennig, A.: Volumen- und Oberflächenmessung in der Mikroskopie. Verh. Anat. Ges. (Jena) 54, 254- 265 (1957)Google Scholar
  19. Kuwabara, T., Weidman, T.A.: Development of the prenatal rat retina. Invest. Ophthal. 13, 725–739 (1974)PubMedGoogle Scholar
  20. Meiler, K.: Histo- und Zytogenese der sich entwickelnden Retina. Veröffentlichungen aus der morphologischen Pathologie, Heft 77, Stuttgart: Fischer 1968Google Scholar
  21. Ogneff, J.: Histogenese der Retina. Zentralbl. Med. Wiss. 35, 641–645 (1881)Google Scholar
  22. Olney, J.W.: An electron microscopic study of synapse formation, receptor outer segment development, and other aspects of developing mouse retina. Invest. Ophthal. 7, 250–268 (1968)PubMedGoogle Scholar
  23. Schultze, M.: Über Stäbchen und Zapfen der Retina. Arch. Mikrosk. Anat. 3, 215–247 (1867a)CrossRefGoogle Scholar
  24. Schultze, M.: Bemerkungen über Bau und Entwicklung der Retina. Arch. Mikrosk. Anat. 3, 371–382 (1867b)CrossRefGoogle Scholar
  25. Sjöstrand, F.S.: The ultrastructure of the outer segments of rods and cones of the eye as revealed by electron microscope. J. Cell. Comp. Physiol. 42, 15–44 (1953)CrossRefGoogle Scholar
  26. Spira, A.W.: In utero development and maturation of the retina of a non-primate mammal: a light and electron microscopic study of the guinea pig. Anat. Embryol. 146, 279–300 (1975)PubMedCrossRefGoogle Scholar
  27. Tokuyasu, K., Yamada, E.: The fine structure of the retina studied with the electron microscope: IV. Morphogenesis of outer segments of retinal rods. J. Biophys. Biochem. Cytol. 6, 225–231 (1959)PubMedCrossRefGoogle Scholar
  28. Vogel, M.: Postnatal development of the cat’s retina. Ergeb. Anat. Entwickl.-Gesch. 54, (4), 1–66 (1978)Google Scholar
  29. Weidman, T.A.: Fine structure of developing retina. Internat. Ophthal. Clinics (Boston) 15, 65–84 (1975)CrossRefGoogle Scholar
  30. Weidman, TA., Kuwabara, T.: Postnatal development of the rat retina. Arch. Ophthal. 79, 470–484 (1968)PubMedCrossRefGoogle Scholar
  31. Yamada, E., Ishikawa, T.: Some observations on the submicroscopic morphogenesis of the human retina. In: The Structure of the Eye. Rohen, J.W., II. Symp., pp. 5–16. Stuttgart: Schattauer, 1965Google Scholar
  32. Young, R.W.: The renewal of photoreceptor cell outer segments. J. Cell Biol. 33, 61–72 (1967)PubMedCrossRefGoogle Scholar
  33. Young, R.W.: A difference between rods and cones in the renewal of outer segment protein. Invest. Ophthal. 8, 222–231 (1969)PubMedGoogle Scholar
  34. Young, R.W.: The renewal of rod and cone outer segments in the rhesus monkey. J. Cell Biol. 49, 303–318 (1971)PubMedCrossRefGoogle Scholar
  35. Young, R.W.: Visual cells and the concept of renewal. Invest. Ophthalmol. 15, 700–725 (1976)Google Scholar
  36. Young, R. W., Bok, D.: Participation of the retinal pigment epithelium in the rod outer segment renewal process. J. Cell Biol. 42, 392–403 (1969)PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1978

Authors and Affiliations

  • Margarete Vogel
    • 1
  1. 1.Department of AnatomySchool of MedecineLübeckFederal Republic of Germany

Personalised recommendations