Abstract
The main energy-transducing enzymes of the mitochondrial inner membrane are organized as distinct multiprotein complexes (Fig. 1), oxidoreductases (complexes I, III, and IV), which transduce the energy generated by multiple oxidation-reduction reactions into an intermediate energy form that can be used by the ATP-synthetase (complex V) for the formation of ATP (for review see Hatefi, 1978).
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References
Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F.: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Berlin, New York: Walter de Gruyter, 1977
Beattie, D.S.: Studies on the Biogenesis of Mitochondrial Protein Components in Rat Liver Slices. J. Biol. Chem. 243, 4027 – 4033 (1968)
Borst, P.: Mitochondrial Nucleic Acids. Ann. Rev. Biochem. 41, 333 – 376 (1972)
Borst, P., Bos, J.L., Grivell, L.A., Groot, G.S.P., Heyting, C., Moorman, A.F.M., Sanders, J.P.M., Talen, J.L., van Kreijl, C.F., van Ommen, G.J.B.: The Physical Map of Yeast Mitochondrial DNA Anno 1977 (A Review). In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977, pp. 213 – 254
Brosemer, R.W., Vogell, W., Bücher, Th.: Morphologische und enzyrratische Muster bei der Entwicklung indirekter Flugmuskeln von Locusta migratoria. Biochem. Z. 338, 854 – 910 (1963)
Bücher, Th., Neupert, W., Sebald, W., Werner, S.: Genetics and Biogenesis of Chloroplasts and Mitochondria. Amsterdam-New York-Oxford: North Holland, 1976
Burger, G., Lang, B., Bandlow, W., Schweyen, R.J., Backhaus, B., Kaudewitz, F.:A New Mutation on the mit DNA Conferring Antimycin Resistance on the Mitochondrial Respiratory Chain. Biochem. Biophys. Res. Commun. 72, 1201 – 1208 (1976)
Casey, J.W., Hsu, H.J., Getz, G.S., Rabinowitz, M., Fukuhara, H.: Transfer RNA Genes in Mitochondrial DNA of Grande (Wild-type) Yeast. J. Mol. Biol. 88, 735–747 (1974)
Claisse, M., Spyridakis, A., Slonimski, P.P.: Mutations at any one of the Three Unlinked Mitochondrial Genetic Loci Box 1, Box 4 and Box 6 Modify the Structure of Cytochrome b Polypeptide(s). In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977, pp. 337 – 344
Clark-Walker, G.D., Linnane, A.W.: In Vivo Differentiation of Yeast Cytoplasmic and Mitochondrial Protein Synthesis with Antibiotics. Biochem. Biophys. Res. Commun. 25, 8 – 13 (1966)
Colson, A.M., Slonimski, P.S.: Mapping of Drug-Resistant Loci in the Coenzyme QH2Cytochrome C Reductase Region of the Mitochondrial DNA Map in Saccharomyces cerevisiae. In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977, pp. 185 – 196
Colson, A.M., The Van, L., Convent, B., Briquet, M., Goffeau, A.: Mitochondrial Heredity of Resistance to 3, (3,4-Dichlorophenyl)-1,1-dimethylurea, an Inhibitor of Cytochrome b Oxidation in Saccharomyces cerevisiae. Eur. J. Biochem. 74, 521–526 (1977)
Dujon, B., Colson, A.M., Slonimski, P.O.: The Mitochondrial Genetic Map of Saccharomyces cerevisiae: Compilations of Mutations, Genes, Genetic and Physical Maps. In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Bandlow, W., Schweyer, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977,pp. 577–669
Fukuhara, H., Martin, N., Rabinowitz, M.: Isoaccepting Mitochondrial Glutamyl-tRNA Species Transcribed from Different Regions of the Mitochondrial Genome of Saccharomyces cerevisiae. J. Mol. Biol. 101, 285 – 296 (1976)
Hatefi, Y., Galante, J.M.: Organization of the Mitochondrial Respiratory Chain. This volume, pp.
Jagow, G., von, Schägger, H., Riccio, P., Klingenberg, M., Kolb, H.J.: Bc1 Complex from Beef Heart: Hydrodynamic Properties of the complex Prepared by a Refined
Hydroxyapatite Chromatography in Triton X-100. Biochim. Biophys. Acta 462, 549–558 (1977)
Katan, M.B., Van-Harten-Loosbroek, N., Groot, G.S.P.: The Cytochrome bc1 Complex of Yeast Mitochondria. Site of Translation of the Polypeptides in vivo. Eur. J. Biochem. 70, 409 – 417 (1976)
Keilin, D., Hartree, E.F.: Relationship between Certain Components of the Cytochrome System. Nature (London) 176, 200 – 206 (1955)
Kotylak, Z., Slonimski, P.P.: Fine Structure Genetic Map of the Mitochondrial DNA Region Controlling Coenzyme QH2-Cytochrome c Reductase. In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977, pp. 161 – 172
Lorenz, B., Kleinow, W., Weiss, H.: Mitochondrial Translation of Cytochrome b in Neurospora crassa and Locusta migratoria. Z. Physiol. Chem. 355, 300 – 304 (1974)
Mager, J.: Chloramphenicol and Chlortetracycline Inhibition of Amino Acid Incorporation into Protein Cell Free System from Tetrahymina Pyriformis. Biochim. Biophys. Acta 38, 10 – 15 (1960)
Moser, U.K., Walter, P.: A New Specific Inhibitor of the Respiratory Chain in Rat Liver Mitochondria. FEBS Lett. 50, 279 – 282 (1975)
Obbink, D.J.G., Spithill, T.W., Maxwell, R.J., Linnane, A.W.: A Mitochondrial Mutation conferring Resistance to an Antimycin A-Like Contaminant in Mikamycin. Mol. Gen. Genet. 151, 127 – 136 (1977)
Pratje, E., Michaelis, G.: Allelism Studies of Mitochondrial Mutants Resistant to Antimycin A or Funiculosin in Saccharomyces cerevisiae. Mol. Gen. Genet. 152, 167 – 174 (1977)
Putrament, A., Baranowska, H., Pazmo, W.: Induction by Manganese of Mitochondrial Antibiotic Resistance Mutations in Yeast. Mol. Gen. Genet. 126, 357–366 (1973)
Reijnders, L., Borst, P.: The Number of 4-S RNA Genes on Yeast Mitochondrial DNA.Biochem. Biophys. Res. Commun. 47, 126–133 (1972)
Reijnders, L., Kleisen, C.M., Grivell, L.S., Borst, P.: Hybridization Studies with Yeast Mitochondrial RNAs. Biochem. Biophys. Acta 272, 396–407 (1972)
Rieske, J.S.: Composition, Structure.and Function of Complex III of the Respiratory Chain. Biochim. Biophys. Acta 456, 195–247 (1976)
Saccone, C., Kroon, A.M.: The Genetic Function of Mitochondrial DNA. AmsterdamOxford-New York: North-Holland, 1976
Schatz, G., Saltzgaber, J.: Protein Synthesis by Yeast Promitochondria in vivo. Biochem. Biophys. Res. Commun. 37, 996–1001 (1969)
Sebald, W., Schwab, A.J., Bücher, Th.: Cycloheximide Resistant Amino Acid Incorporation into Mitochondrial Protein from Neurospora crassa. FEBS Lett. 4, 243–246 (1969)
Sebald, W., Weiss, H., Jackl, G.: Inhibition of the Assembly of Cytochrome Oxidase in Neurospora crassa by Chloramphenicol. Eur. J. Biochem. 30, 413–417 (1972)
Slonimski, P.P., Tzagoloff, A.: Localization in Yeast Mitochondrial DNA of Mutations Expressed in a Deficiency of Cytochrome Oxidase and/or Coenzyme QH2-Cytochrome c Reductase. Eur. J. Biochem. 61, 27–41 (1976)
Subik, J., Behun, M., Musilek, V.: Antibiotic Mucidin, a New Antimycin A-Like Inhibitor of Electron Transport in Rat Liver Mitochondria. Biochem. Biophys. Res. Commun. 57, 17–22 (1974)
Subik, J., Kovacova, V., Takacsova, G.: Mucidin Resistance in Yeast. Isolation Characterization and Genetic Analysis of Nuclear and Mitochondrial Analysis of Nuclear and Mitochondrial Mucidin Resistant Mutants of Saccharomyces cerevisiae. Europ. J. Biochem. 73, 275–286 (1977)
Tzagoloff, A., Akai, A., Needleman, R.B.: Assembly of the Mitochondrial Membrane System: Isolation of Nuclear and Cytoplasmic Mutants of Saccharomyces cerevisiae with Specific Defects in Mitochondrial Functions. J. Bacteriol. 122, 826–831 (1975)
Tzagoloff, A., Akai, A., Needleman, R.B., Zulch, G.: Assembly of the Mitochondrial Membrane System. Cytoplasmic Mutants of Saccharomyces cerevisiae with Lesions in Enzymes of the Respiratory Chain and in the Mitochondrial ATPase. J. Biol. Chem. 250, 8236–8242 (1975)
Tzagoloff, A., Foury, F., Akai, A.: Resolution of the Mitochondrial Genome. In:The Genetic Function of Mitochondrial DNA. Saccone, C., Kroon, A.M. (eds.) Amsterdam-Oxford-New York: North-Holland, 1976a, pp. 155–161
Tzagoloff, A., Foury, F., Akai, A.: Assembly of the Mitochondrial Membrane System XVIII. Genetic Loci on Mitochondrial DNA Involved in Cytochrome b Biosynthesis. Mol. Gen. Genet. 149, 33–42 (1976b)
Weiss, H.: Subunit Composition and Biogenesis of Mitochondrial Cytochrome b. Biochim. Biophys. Acta 456, 291–313 (1976)
Weiss, H., Juchs, B.: Isolation of a Multiprotein Complex Containing Cytochrome b and cl from Neurospora crassa Mitochondria by Affinity Chromatography on Immobilized Cytochrome c. Difference in the Binding between Ferri-and Ferro-cytochrome c to the Multiprotein Complex. Eur. J. Biochem., in press
Weiss, H., Juchs, B., Ziganke, B.: Complex III from Mitochondria of Neurospora crassa: Purification, Characterization and Resolution. In: Methods in Enzymology. Biomembranes. Fleischer, S., Packer, L. (eds.) New York: Academic Press, in press
Weiss, H., Sebald, W., Schwab, A.J., Kleinow, W., Lorenz, B.: Contribution of Mitochondrial and Cytoplasmic Protein Synthesis to the Formation of Cytochrome b and Cytochrome aa3. Biochimie 55, 815–821 (1973)
Weiss, H., Ziganke, B.: Cytochrome b in Neurospora crassa Mitochondria. Site of Translation of the Heme Protein. Eur. J. Biochem. 41, 63–71 (1974)
Weiss, H., Ziganke, B.: Partial Identification, Stoicheometry and Site of Translation of the Subunits of Ubiquinone: Cytochrome c Oxidoreductase. In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria, Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977, pp. 463–472
Wikström, M.R.F.: The Different Cytochrome b Components in the Respiratory Chain of Animal Mitochondria and their Role in Electron Transport and Energy Conservation. Biochim. Biophys. Acta 301, 155–193 (1973)
Williamson, D.H., Johnston, L.H., Richmond, K.M.V., Game, J.C.: Mitochondria DNA and the Heritable Unit of the Yeast Mitochondrial Genome: a Review. In: Mitochondria 1977, Genetics and Biogenesis of Mitochondria. Bandlow, W., Schweyen, R.J., Wolf, K., Kaudewitz, F. (eds.) Berlin, New York: Walter de Gruyter, 1977, pp. 1–24
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Weiss, H. (1978). Contribution of the Mitochondrial Genetic System to the Biogenesis of Ubiquinone: Cytochrome c Oxidoreductase. In: Schäfer, G., Klingenberg, M. (eds) Energy Conservation in Biological Membranes. Colloquium der Gesellschaft für Biologische Chemie, vol 29. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81287-3_3
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DOI: https://doi.org/10.1007/978-3-642-81287-3_3
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