Neoplasms of Immunoglobulin-Producing Cells in Mice

  • N. L. Warner
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 64)


Although murine lymphoid tumors have been extensively used in experimental tumor research for many decades, their use has principally been related to virologic aspects and to studies of tumor immunity. In recent years, however, considerable interest has developed in their possible application as models of discrete lymphoid subpopulations. The underlying concept, based in part on studies of human lymphoid neoplasia, is that each lymphoid tumor represents the monoclonal neoplastic proliferation of a cell that belongs to a specific T- or B-cell subpopulation and is arrested in its differentiation at a particular stage.


Cold Spring Harbor Lymphoid Tumor Plasma Cell Tumor Differentiation Arrest Membrane Immunoglobulin 
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© Springer-Verlag Berlin · Heidelberg 1978

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  • N. L. Warner

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