Evolution of Immunoblastic Lymphoma in Angioimmunoblastic Lymphadenopathy

  • B. N. Nathwani
  • H. Rappaport
  • E. M. Moran
  • G. A. Pangalis
  • H. Kim
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 64)


Angioimmunoblastic lymphadenopathy (AILD) [4, 5] or immunoblastic lymphadenopathy [7] is a systemic disease clinically characterized by fever, generalized lymphadenopathy, and hepatosplenomegaly. Polyclonal hypergammaglobulinemia, and Coombs’ positive hemolytic anemia are frequently present. The lymph nodes in AILD reveal a polymorphic picture consisting of a proliferation of small vessels, immunoblasts, and plasma cells. Similar clinical and histologic observations have been reported under other designations [3,10,14].


Plasma Cell Malignant Lymphoma Extranodal Involvement Serum Immunoglobulin Level Diffuse Cluster 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1978

Authors and Affiliations

  • B. N. Nathwani
  • H. Rappaport
  • E. M. Moran
  • G. A. Pangalis
  • H. Kim

There are no affiliations available

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