The Structure of Multisubunit Proteins
Regulatory enzymes are multisubunit structures. Structural analysis of regulatory enzymes has in every single instance revealed that the subunits interact with each other by way of specific noncovalent bonds. The subunits always form a well-defined geometrical structure, and the architecture obtained determines to a large extent the regulatory properties of the protein. It will therefore be necessary for us to discuss in some detail the principles of design of oligomeric proteins.
KeywordsPyruvate Carboxylase Point Group Symmetry Oligomeric Structure Oligomeric Protein Subunit Interaction
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