Abstract
While we most often relate antibiotic chemotherapy to erradication of infectious foreign organisms, we must remain aware of the value of antibiotics (e.g. anthracyclines, bleomycin, actinomycin D, mitomycin C, mithramycin, L-asparaginase) as antitumor drugs [5, 12]. Moreover, fermentation products continue to represent a fruitful field for discovering new materials with clinical anticancer potential. During 1976, the Division of Cancer Treatment (DCT), National Cancer Institute (NCI) examined over 1000 fermentation broths for activity against one or more animal tumors. The yield of “active” materials from this in vivo screening program are presented elsewhere in this volume [2].
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Venditti, J.M., Johnson, R.K. (1978). In Vivo Antitumor Evaluation of Antibiotics. Selected Results from the Drug Evaluation Program of the National Cancer Institute, U.S.A. In: Carter, S.K., Umezawa, H., Douros, J., Sakurai, Y. (eds) Antitumor Antibiotics. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 63. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81219-4_5
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DOI: https://doi.org/10.1007/978-3-642-81219-4_5
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