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RNA-dependent DNA Polymerase in a “Virus-Free” System

  • G. Bauer
  • P. H. Hofschneider
Conference paper
Part of the Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden book series (MOSBACH, volume 28)

Abstract

RNA-dependent DNA polymerase (reverse transcriptase) is known to be a regular constituent of RNA tumor viruses and of relatives of this viral group. The role of the enzyme during replication of these viruses has been clarified (1; see also H. Varmus, this Volume). The viral reverse transcriptase synthesizes a double-stranded DNA copy of the viral RNA genome. This DNA (the “provirus”) is subsequently integrated into the host genome and transcribed like a cellular gene.

Keywords

Polymerase Gene Avian Leukosis Virus Particle Enzyme Globin mRNA Avian Sarcoma Virus 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • G. Bauer
  • P. H. Hofschneider

There are no affiliations available

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