RNA-dependent DNA Polymerase in a “Virus-Free” System

  • G. Bauer
  • P. H. Hofschneider
Conference paper
Part of the Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden book series (MOSBACH, volume 28)

Abstract

RNA-dependent DNA polymerase (reverse transcriptase) is known to be a regular constituent of RNA tumor viruses and of relatives of this viral group. The role of the enzyme during replication of these viruses has been clarified (1; see also H. Varmus, this Volume). The viral reverse transcriptase synthesizes a double-stranded DNA copy of the viral RNA genome. This DNA (the “provirus”) is subsequently integrated into the host genome and transcribed like a cellular gene.

Keywords

Glycerol Leukemia Recombination Sedimentation Sarcoma 

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Copyright information

© Springer-Verlag Berlin Heidelberg 1978

Authors and Affiliations

  • G. Bauer
  • P. H. Hofschneider

There are no affiliations available

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