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RNA-dependent DNA Polymerase in a “Virus-Free” System

  • Conference paper
Integration and Excision of DNA Molecules

Part of the book series: Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden ((MOSBACH,volume 28))

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Abstract

RNA-dependent DNA polymerase (reverse transcriptase) is known to be a regular constituent of RNA tumor viruses and of relatives of this viral group. The role of the enzyme during replication of these viruses has been clarified (1; see also H. Varmus, this Volume). The viral reverse transcriptase synthesizes a double-stranded DNA copy of the viral RNA genome. This DNA (the “provirus”) is subsequently integrated into the host genome and transcribed like a cellular gene.

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Authors
  1. G. Bauer
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  2. P. H. Hofschneider
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Editor information

Editors and Affiliations

  1. Max-Planck-Institut für Biochemie, 8033, Martinsried/München, Germany

    Peter Hans Hofschneider

  2. Institut für Genetik, Universität Köln, Weyertal 121, 5000, Köln 41, Germany

    Peter Starlinger

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© 1978 Springer-Verlag Berlin Heidelberg

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Bauer, G., Hofschneider, P.H. (1978). RNA-dependent DNA Polymerase in a “Virus-Free” System. In: Hofschneider, P.H., Starlinger, P. (eds) Integration and Excision of DNA Molecules. Colloquium der Gesellschaft für Biologische Chemie in Mosbach Baden, vol 28. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81203-3_14

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  • DOI: https://doi.org/10.1007/978-3-642-81203-3_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81205-7

  • Online ISBN: 978-3-642-81203-3

  • eBook Packages: Springer Book Archive

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