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Nuklearmedizinische in vitro-Diagnostik

  • W. Finck
Part of the Handbuch der Medizinischen Radiologie / Encyclopedia of Medical Radiology book series (HDBRADIOL, volume 15 / 2)

Zusammenfassung

Der Einsatz von nuklearmedizinischen Verfahren zur Analytik von Substanzen, die aufgrund ihrer geringen Konzentration in Körperflüssigkeiten oder wegen ihrer für die Analytik nicht günstigen Eigenschaften mit anderen Verfahren nicht oder nur mit hohem Aufwand meßbar sind, hat seit der Einführung im Jahr 1960 eine stürmische Entwicklung genommen. Aus einer Untersuchungsmethode, Anfang der sechziger Jahre noch beschränkt auf einige wenige Einrichtungen, die sich mit diesem Problem speziell beschäftigten, sich die wissenschaftlich-methodischen Grundlagen erst selbst erarbeiteten und die benötigten Analytika z.T. selbst herstellten, ist in diesem kurzen Zeitraum ein allgemein angewandtes Routineverfahren mit einem breiten Anwendungsspektrum geworden, mit kommerziell gefertigten und angebotenen Untersuchungsbestecken und mit relativ gesicherten theoretischen Grundlagen. Das Analysenspektrum ist weit: für Hormone, Vitamine, Kinine, Metaboliten des Intermediärstoffwechsels und Pharmaka sind Verfahren auf der Basis der nuklearmedizinischen in vitro-Diagnostik entwickelt worden.

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