Abstract
The molecular world is a world of discrete entities which are in ceaseless motion, even when a system is at equilibrium. This motion, although it is correctly described as “random” and “chaotic”, nevertheless may be studied systematically by Concentration Correlation Analysis (CCA).
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ARAGON, S.R., PECORA, R.: Fluorescence correlation spectroscopy and Brownian rotational diffusion. Biopolymers 14, 119–137 (1975)
BERNE, B.J.: Chemical and biological applications of laser lightscattering. Acc. Chem. Res. 6, 318–322 (1973)
BLOOMFIELD, V.A., BENBASAT, J.A.: Inelastic light scattering study of macromolecular reaction kinetics. I. The Reactions A⇌B and 2A⇌A2. Macromolecules 4, 609–617 (1971)
CALLEN, H.B., GREENE, R.F.: On a theorem of irreversible thermodynamics. Phys. Rev. 86, 702–710 (1952)
CHEN, Y.: Fluctuations and noise in kinetic systems. II. Open ensembles at equilibrium and steady state. J. Chem. Phys. 59, 5810–5813 (1973)
CHEN, Y., HILL, T.L.: Fluctuations and noise in kinetic systems, application to K+ channels in the squid axon. Biophys. J. 13, 1276–1295 (1973)
CUMMINS, H.Z., CARLSON, F.D., HERBERT, T.J., WOODS, G.: Translational and rotational diffusion constants of tobacco mosaic virus from Rayleigh linewidths. Biophys. J. 9, 518–546 (1969)
DEGIORGIO, V., LASTOVKA, J.B.: Intensity - correlation spectroscopy. Phys. Rev. A4, 2033–2050 (1971)
EHRENBERG, M., RIGLER, R.: Rotational Brownian motion and fluorescence intensity fluctuations. Chem. Phys. 4, 390–401 (1974)
ELSON, E.L., MAGDE, D.: Fluorescence correlation spectroscopy. I. Conceptual basis and theory. Biopolymers 13, 1–27 (1974)
FEHER, G.: Determination of kinetic parameters from the frequency spectrum of fluctuations. Biophys. Soc. Abstracts 10, 118a (1970)
FEHER, G., WEISSMAN, M.: Fluctuation spectroscopy: determination of chemical reaction kinetics from the frequency spectrum of fluctuations. Proc. Nat. Acad. Sci. (Wash.) 70, 870–875 (1973)
FLEURY, P.A., BOON, J.P.: Laser light scattering in fluid systems. In: Advances in Chemical Physics. PRIGOGINE, I., RICE, S.A. (eds.); Vol. XXIV, pp. 1–93. New York: Interscience 1973 (This very broad survey includes an extensive bibliography.)
GREENE, R.F., CALLEN, H.B.: On the formalism of thermodynamic fluctuation theory. Phys. Rev. 83, 1231–1235 (1951)
GREENE, R.F., CALLEN, H.B.: On a theorem of irreversible thermodynamics. II. Phys. Rev. 88, 1387–1391 (1952)
HERBERT, T.J., WEBB, W.W., ELSON, E.L.: Lateral diffusion in lipid membranes, in preparation (1976)
HUGHES, A.J., JACKEMAN, E., OLIVER, C.J., PIKE, E.R.: Photocorrelation spectroscopy: dependence of linewidth error on normalization, clip level, detector area, sample time, and count rate. J. Phys. A: Math., Nucl., Gen. 6, 1327–1336 (1973)
JOHNSON, D.H., WEBB, W.W.: Measurement of the rate of strain tensor in a turbulent liquid using light scattered from asymmetric particles. Bull. Am. Phys. Soc. 17, 1084 (1972); additional results in preparation.
KELLY, H.C.: A comparison of the information-gathering capacities of photon correlation devices. IEEE J. Quantum Electron. QE-7, 541–550 (1971)
KOPPEL, D.E.: Statistical accuracy in fluorescene correlation spectroscopy. Phys. Rev. A-10, 1938–1945 (1974)
KOPPEL, D.E., SCHAEFER, D.W.: Scaled photocount correlation of non-gaussian scattered light. Appl. Phys. Lett. 22, 36–37 (1973)
MAGDE, D., ELSON, E., WEBB, W.W.: Thermodynamic fluctuations in a reacting system-measurement by fluorescence correlation spectroscopy. Phys. Rev. Lett. 29, 705–708 (1972)
MAGDE, D., ELSON, E.L., WEBB, W.W.: Fluorescence correlation spec-troscopy. II. An experimental realization. Biopolymers 13, 29–61 (1974)
PECORA, R.: Quasi-elastic light scattering from macromolecules. Ann. Rev. Biophys. and Bioeng. J, 257–2 76 (1972)
SCHAEFER, D.W.: Dynamics of number fluctuations; motile microorganisms. Science 180, 1293–1295 (1973)
SCHAEFER, D.W., BERNE, B.J.: Light scattering from non-gaussian concentration fluctuations. Phys. Rev. Lett. 28, 475–478 (1972)
SCHAEFER, D.W., PUSEY, P.N.: Statistics of non-gaussian light. Phys. Rev. Lett. 29, 843–845 (1972)
SCHMITZ, K.S., SCHURR, J.M.: Rotational relaxation of macromolecules determined by dynamic light scattering. II. Temperature dependence for DNA. Biopolymers 12, 1543–1564 (1973)
SCHURR, J.M., SCHMITZ, K.S.: Rotational relaxation of macromolecules determined by dynamic light scattering. I. Tobacco mosaic virus. Biopolymers 12, 1021–1045 (1973)
SINGER, S.J., NICOLSON, G.L.: The fluid mosaic model of the structure of cell membranes. Science 175, 720–731 (1972)
WEISSMAN, M., FEHER, G.: Observation of energy (thermal) fluctuations in an electrolyte solution. J. Chem. Phys. 63, 586–587 (1975)
YEH, Y.: Experimental study of reaction kinetics by light scattering. II. Helixcoil transition of the copolymer deoxyadenylate- deoxythymidate (dAT). J. Chem. Phys. 52, 6218–6224 (1970)
YEH, Y., KEELER, R.N.: Experimental study of reaction kinetics by light scattering. I. The polarized Rayleigh component. J. Chem. Phys. 51, 1120–1127 (1969a)
YEH, Y., KEELER, R.N.: New Probe for reaction kinetics - The spectrum of scattered light. Quart. Rev. Biophys. 2, 315–349 (1969b)
ZINGSHEIN, H.P., NEHER, E.: The equivalence of fluctuation analysis and chemical relaxation measurements: A kinetic study of ion pore formation in thin lipid membrane. Biophys. Chem. 2, 197–207 (1974)
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Magde, D. (1977). Concentration Correlation Analysis and Chemical Kinetics. In: Pecht, I., Rigler, R. (eds) Chemical Relaxation in Molecular Biology. Molecular Biology Biochemistry and Biophysics, vol 24. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81117-3_2
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DOI: https://doi.org/10.1007/978-3-642-81117-3_2
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