Aspiration Biopsy Cytology of Prostate Carcinoma

  • H. Nienhaus
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 60)


Aspiration biopsy cytology was inaugurated by FRANZÉN, ZAJICEK and ESPOSTI in 1950 from their Institute of Clinical Cytology at Karolinska Academy, Stockholm; the method attained high technical and diagnostical standards during the following years (24). Besides exfoliative cytology and histology, aspiration biopsy cytology must be accepted as an independent approach to morphologic diagnosis and as an instrument of research. In contrast to routine preparations in exfoliative cytology or in histology, the needle preparation allows detailed and parallel examination of the cell and of the histologic structure, resulting in better documented diagnosis. As in various other organs, e.g., in the thyroid or in the breast, the detection of a carcinoma in the prostate is 10% more safe by aspiration biopsy than by mere histologic biopsy. Subsequent histologic counter-checking seldom fails to confirm a positive diagnosis based upon needle preparations (5, 6, 10, 14, 15, 21).


Aspiration Biopsy Streaky Structure Exfoliative Cytology Aspiration Biopsy Cytology Routine Preparation 
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© Springer-Verlag Berlin Heidelberg 1977

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  • H. Nienhaus

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