Abstract
Feminization and precocious pubertal development are manifestations of hormone production by both benign and malignant testicular tumors. The pathophysiologic mechanisms underlying these clinical syndromes vary not only with the cell type of the tumor but also with the age of the host. Recent refinements in the ability to measure both steroidal and polypeptide hormones have provided both a new insight into these mechanisms and also useful parameters for monitoring therapy in these disorders.
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Braunstein, G.D. et al.: Ectopic production of human chorionic gonadotropin by neoplamss. Ann. intern. Med. 78, 39–45 (1973)
Braunstein, G.D. et al.: Discordance of human chorionic gonadotropin and alpha-fetoprotein in testicular teratocarcinomas. Cancer (Philad.) 31, 1065–1068 (1973)
Cochran, J. et al.: The endocrinology of human chorionic gonadotropin-secreting testicular tumors: New methods in diagnosis. J. Urol. (Baltimore) (In Press)
Dixon, F.J., Moore, R.A.: Tumors of the male sex organs. In: Atlas of Tumor Pathology; Dixon, F.J., Moore, R.A. (eds.). Washington, D.C.: Armed Forces Inst. Path., 1952, Sect. VIII, Fasc. 32
Frantz, A.G. et al.: Human placental lactogen in choriocarcinoma of the male. Measurement by radioimmunoassay. J. clin. Endocr. 25, 1136–1139 (1965)
Gabrilove, J.L. et al.: Feminizing interstitial cell tumor of the testis: Personal observations and a review of the literature. Cancer (Philad.) 35, 1184–1202 (1975)
Hobson, B.M.: The excretion of chorionic gonadotropin by men with testicular tumors. Acta endocr. (Kbh.) 49, 337–348 (1965)
Kirschner, M.A. et al.: Leydig cell function in men with gonadotropin-producing testicular tumors. J. clin. Endocr. 30, 504–511 (1 970)
Kirschner, M.A. et al.: Estrogen production and its origin in men with gonadotropin-producing neoplasms. J. clin. Endocr. 39, 112118 (1974)
Kliman, B. et al.: Estradiol secreting Leydig cell tumor. Proc. 55th Ann. Meet. Endocrine Soc. 1973
Payne, R.A., Ryan, R.J.: Human placental lactogen in the male subject. J. Urol. (Baltimore) 99–103 (1972)
Pierrepoint, C.G.: The metabolism in vitro of dehydroepiandrosterone and dehydroepiandrosterone sulfate by Sertoli cell tumors of the testis of two dogs with clinical signs of hyperestrogenism. J. Endocr. 42, 99–107 (1968)
Selvaggi, F.P. et al.: Interstitial cell tumor of the testis in adults - Two case reports. J. Urol. (Baltimore) 109, 436 (1973)
Siiteli, P.K., MacDonald, P.C.: Role of extraglandular estrogen in human endocrinology. In: Handbook of Physiology. 7. Endocrinology Vol. II. Greep, R.O., Astwood, E.B. (eds.). Washington, D.C.: Amer. physiol. Soc. 1973, pp. 615–629
Talerman, A.: Malignant Sertoli cell tumor of the testis. Cancer (Philad.) 28, 446–455 (1971)
Villee, D.B.: Development of endocrine function in the human placenta and fetus. Med. Progr. 281, 473–541 (1969)
Weinstein, R.L. et al.: Secretion of unconjugated androgens and estrogens by the normal and abnormal human testis before and after human chorionic gonadotropin. J. clin. Invest. 53, 1–6 (1974)
Weintraub, B.D., Rosen, S.W.: Ectopic production of human chorionic somatomammotropin by nontrophoblastic cancers. J. clin. Endocr. 32, 94–101 (1971)
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© 1977 Springer-Verlag Berlin Heidelberg
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Walsh, P.C. (1977). The Endocrinology of Testicular Tumors. In: Grundmann, E., Vahlensieck, W. (eds) Tumors of the Male Genital System. Recent Results in Cancer Research, vol 60. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81095-4_20
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DOI: https://doi.org/10.1007/978-3-642-81095-4_20
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