Abstract
The organisers of this Symposium have asked me to give a short pladoyer for the macrophage and its position in the immune system. I would like to open this case with two statements:
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1.
The specificity of the immune response is a sole function of committed lymphocytes. Macrophages do not play an instructional role.
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2.
Phagocytosis was the primordial mechanism of defence; the specific elements, the lymphocytes, came later.
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References
Furth, R. van (ed.): Mononuclear Phagocytes. Oxford and Edinburgh: Blackwell Sci. Publ. 1970
Furth, R. van (ed.): Phagocytes in Immunity, Infection and Pathology. Oxford: Blackwell Sci. Publ. 1975
Wagner, H.W., Hahn, H. (eds.): Workshop Conference Hoechst, Vol. II. Excerpta Medica Amsterdam. New York: American Elsevier Publ. Co. 1974
Unanue, E.R.: J. Immunol. 105 (1970)
Matthes, M.-L., Ax, W., Fischer, H.: In: Cell Interactions and Receptor Antibodies in Immune Responses. Mäkelä, O., Cross, A., Kosunen, T.U. (eds.). London, New York: Academic Press 1971
Matthes, M.-L., Ax, W., Fischer, H.: Z. Ges. Exp. Med. 154, 253–264 (1971)
Unanue, E.R., Calderon, J.: Federation Proc. 34, 1737–1742 (1975)
Ritter, J., Lohmann-Matthes, M.-L., Sonntag, H.G., Fischer, H.: Cell. Immunol. 16, 153–161 (1975)
Rosenthal, A.S., Lipsky, P.E., Shevach, E.M.: Federation Proc. 34, 1743–1748 (1975)
Mackaness, G.G.: J. Exp. Med. 129, 973–984 (1969)
Mackaness, G.B., Lagrange, P.H., Miller, T.E., Ishibashi, T.: In: Activation of Macrophages. Workshop Conference Hoechst, Vol. II. (Wagner, H.W., Hahn, H. (eds.). Excerpta Medica, Amsterdam. New York: American Elsevier Publ. Co. 1974
David, J.R.: Federation Proc. 34, 1730–1736 (1975)
Lohmann-Matthes, M.-L., Fischer, H.: Transpl. Rev. 17, 151–171 (1973)
Meerpohl, H.G., Lohmann-Matthes, M.-L., Fischer, H.: Europ. J. Immunol. 6, 213–217 (1976)
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Fischer, H. (1976). Macrophages. In: Melchers, F., Rajewsky, K. (eds) The Immune System. Colloquium der Gesellschaft für Biologische Chemie, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81083-1_13
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DOI: https://doi.org/10.1007/978-3-642-81083-1_13
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