Skip to main content

T Lymphocytes

  • Conference paper
The Immune System

Part of the book series: Colloquium der Gesellschaft für Biologische Chemie ((MOSBACH,volume 27))

  • 200 Accesses

Abstract

The small lymphocytes are the cells in the body of an immunocompetent individual, which are able to initiate a specific immune response against foreign material due to their own, predetermined immune reactivity. Although these cells look strikingly similar when observed under conventional light microscopy unsurpassed heterogeneity resides in this cellpopulation as to surface markers and functional activities. Two major groups of lymphocytes comprise this diverse population, the B and the T lymphocytes (17). These two types of cells differentiate according to their own distinct pathways and no evidence exists that a T lymphocyte can convert itself into a B lymphocyte or vice versa. The functions of the B lymphocytes are seemingly not manifold, but appear to reside in their ability to produce humoral antibodies of conventional immunoglobulin type. The T lymphocytes, on the other hand, are known to express a variety of functions including killer cell activity against foreign cells, helper activity for B cells to allow the latter to make antibodies, suppression of the specific helper activity etc. (17, 19, 20).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Andersson, L.C., Häyry, P.: Transpl. Rev. 25, 121 (1975)

    CAS  Google Scholar 

  2. Benacerraf, B., McDevitt, H.O.: Science 175, 273 (1972)

    Article  PubMed  CAS  Google Scholar 

  3. Binz, H., Wigzell, H.: J. Exp. Med. 142, 197 (1975a)

    Article  PubMed  CAS  Google Scholar 

  4. Binz, H., Wigzell, H.: J. Exp. Med. 142, 1218 (1975b)

    Article  PubMed  CAS  Google Scholar 

  5. Binz, H., Wigzell, H.: J. Exp. Med. 142, 1231 (1975c)

    Article  PubMed  CAS  Google Scholar 

  6. Binz, H., Wigzell, H.: Scand. J. Immunol., in press (1976)

    Google Scholar 

  7. Cantor, H., Boyse, E.A.: J. Exp. Med. 141, 1376 (1975a)

    Article  PubMed  CAS  Google Scholar 

  8. Cantor, H., Boyse, E.A.: J. Exp. Med. 141, 1390 (1975b)

    Article  PubMed  CAS  Google Scholar 

  9. Cantor, H.: personal communication

    Google Scholar 

  10. Crone, M., Koch, C., Simonsen, M.: Transpl. Rev. 10, 36 (1972)

    CAS  Google Scholar 

  11. Eichmann, K., Rajewsky, K.: Europ. J. Immunol. 5, 661 (1975)

    Article  CAS  Google Scholar 

  12. Hämmerling, G.J., Black, S.J., Berek, C., Eichmann, K., Rajewsky, K.: J. Exp. Med. 143, 861 (1976)

    Article  PubMed  Google Scholar 

  13. Kimura, A.K., Wigzell, H.: In: Contemporary Topics in Molecular Immunology. New York: Plenum Press 1976, Vol. VI in press

    Google Scholar 

  14. Marchalonis, J.J., Cone, R.E., Atwell, J.L.: J. Exp. Med. 135, 956 (1972)

    Article  PubMed  CAS  Google Scholar 

  15. Munro, A.J., Taussig, M.: Nature 256, 103 (1975)

    Article  PubMed  CAS  Google Scholar 

  16. Ramseier, H., Lindenmann, J.: Transplant. Rev. 10, 57 (1972)

    PubMed  CAS  Google Scholar 

  17. Separation of T and B lymphocyte subpopulations, Transplant. Rev. Möller, G. (ed.). 1975a, vol. 25

    Google Scholar 

  18. Shearer, G.M., Lozner, E.C., Rehn, T.G., Schmitt-Verhulst, A.M.: J. Exp. Med. 141, 930 (1975)

    Article  PubMed  CAS  Google Scholar 

  19. Specificity of effector T lymphocytes. Transplan. Rev. Möller, G. (ed.). 1975b, vol. 26

    Google Scholar 

  20. Herzenberg, L.A., Okumura, K., Cantor, H., Sato, V.L., Chen, F.W., Boyse, E.A., Herzenberg, L.A.: J. Exp. Med. 144, 330 (1976)

    Article  PubMed  CAS  Google Scholar 

  21. Takemori, T., Tada, T.: J. Exp. Med. 142, 1241 (1975)

    Article  PubMed  CAS  Google Scholar 

  22. Wagner, H., Röllinghof, M.: Europ. J. Immunol. 6, 15 (1976)

    Article  CAS  Google Scholar 

  23. Wilson, D.B., Blyth, L.L., Nowell, P.C.: J. Exp. Med. 128, 1157 (1968)

    Article  PubMed  CAS  Google Scholar 

  24. Zinkernagel, R.M., Doherty, P.C.: Nature (Lond.) 248, 701 (1974)

    Article  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1976 Springer-Verlag Berlin · Heidelberg

About this paper

Cite this paper

Wigzell, H. (1976). T Lymphocytes. In: Melchers, F., Rajewsky, K. (eds) The Immune System. Colloquium der Gesellschaft für Biologische Chemie, vol 27. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81083-1_11

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-81083-1_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-81085-5

  • Online ISBN: 978-3-642-81083-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics