Hyperthermic Perfusion of Extremities for Melanoma and soft Tissue Sarcomas

  • J. S. StehlinJr.
  • B. C. Giovanella
  • P. D. de Ipolyi
  • L. R. Muenz
  • R. F. Anderson
  • A. A. Gutierrez
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 59)

Abstract

Since the work of KLOPP (8, 9), CREECH (36) and our group (1316), perfusion has attracted wide attention as a method of treating patients with certain types of malignant neoplasms of the extermities. We began normothermic perfusion in 1957.

Keywords

Catheter Albumin Explosive Bacillus Sarcoma 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Cavaliere, R., Ciocatto, E.L., Giovanella, B.D., Heidelberger, C., Johnson, R.O., Margottini, M., Mondovi, B., Moricca, G., ROSSI- Fanelli, A.: Selective heat sensitivity of cancer cells. Cancer 20, 1351 (1967)PubMedCrossRefGoogle Scholar
  2. 2.
    Clark, W.H., From, L.: The histogenesis and biological behavior of primary human malignant melanomas of the skin. Cancer Res. 29, 29 (1969)Google Scholar
  3. 3.
    Creech, I., Jr., Krementz, E.T., Ryan, R.F., Reemtsma, K., Winblad, J.N.: Experiences with isolation-perfusion technics in the treatment of cancer. Ann. Surg. (Chicago) 149, 627 (1959)Google Scholar
  4. 4.
    Creech, I., Jr., Ryan, R.F., Krementz, E.T.: Treatment of melanoma by isolation-perfusion technique. J. Amer. med. Ass. 169, 339 (1959)CrossRefGoogle Scholar
  5. 5.
    Creech, O., Jr., Krementz, E.T., Ryan, R.F., Reemtsma, K., Winblad, J.N., Elliot, J.L.: Treatment of cancer by perfusion. Arch. Surg. (Chicago) 79, 963 (1959)CrossRefGoogle Scholar
  6. 6.
    Creech, O., Jr., Krementz, E.T., Ryan, R.F., Winblad, J.N.: Chemotherapy of cancer: Regional perfusion utilizing an extra-corporeal circuit. Ann. Surg. 148, 61 6 (1 958)Google Scholar
  7. 7.
    Fine, G., Ohorodnik, J.M., Horn, R.C., Jr.: Soft-tissue sarcomas: Their clinical behavior and course and influencing factors. In: Seventh National Cancer Conference Proceedings ( 1972 ), Philadelphia: J.B. Lippincott Co., 1973Google Scholar
  8. 8.
    Klopp, C.T.: Fractionated intra-arterial cancer chemotherapy with methyl bisamine hydrochloride: A preliminary report. Ann. Surg. 13 2, 811 (1950)CrossRefGoogle Scholar
  9. 9.
    Klopp, C.T., Bateman, J., Bery, N., Alford, C., Winship, T.: Fractionated regional cancer chemotherapy. Cancer Res. 10, 229 (1950)Google Scholar
  10. 10.
    McNEER, G., CANTIN, J.: Local failure in the treatment of melanoma. Amer. J. Roentgenol. 99, 791 (1 967)Google Scholar
  11. 11.
    Stehlin, J.S., Jr.: Hyperthermic perfusion with chemotherapy for cancer of the extremities. Surg. Gynec. Obstet. 129, 305 (1969)PubMedGoogle Scholar
  12. 12.
    Stehlin, J.S., Jr., Clark, R.L.: Chemotherapy for cancer by regional perfusion. Arch. Surg. (Chicago) 83, 196 (1961)CrossRefGoogle Scholar
  13. 13.
    Stehlin, J.S., Jr., Clark, R.L., Jr., Dewey, W.C.: Continuous monitoring of leakage during perfusion. Arch. Surg. (Chicago) 83, 943 (1961)CrossRefGoogle Scholar
  14. 14.
    Stehlin, J.S., Jr., Clark, R.L., Jr., White, E.C., Healey, J.E., Jr., Dewey, W.C., Beerstecher, S.: The leakage factor in regional perfusion of chemotherapeutic agents. Arch. Surg. (Chicago) 80, 934 (1960)CrossRefGoogle Scholar
  15. 15.
    Stehlin, J.S., Jr., Clark, R.L., Jr., White, E.C., Smith, J.L., Jr.: Malignant melanoma of the extremities: Experiences with conventional therapy; A new surgical and chemotherapeutic approach with regional perfusion. Cancer (Philad.) 13, 55 (1960)CrossRefGoogle Scholar
  16. 16.
    Stehlin, J.S., Jr., Clark, R.L., Jr., White, E.C., Smith, J.L., Jr., Griffin, A.C., Jesse, R.H., Jr., Healey, J.E., Jr.: Regional chemotherapy for cancer: Experiences with 116 perfusions. Ann. Surg. 151, 605 (1960)PubMedCrossRefGoogle Scholar
  17. 17.
    Stehlin, J.S., Jr., Giovanella, B.C., de Ipolyi, P.D., Muenz, L.R., Anderson, R.F.: Results of hyperthermic perfusion for melanoma of the extremities. Surg. Gynec. Obstet. 140, 338 (1975)Google Scholar
  18. 18.
    Stehlin, J.S., Jr., de Ipolyi, P.D., Diovanella, B.C., Gutierrez, A.E., Anderson, R.F.: Soft tissue sarcomas of the extremity, multidisciplinary therapy employing hyperthermic perfusion. Amer. J. Surg. 130, 643 (1975)Google Scholar
  19. 19.
    Stehlin, J.S., Jr., Smith, J.L., Jing, B., Sherrin, D.: Melanomas of the extremities complicated by in-transit metastases. Surg. Gynec. Obstet. 122, 3 (1966)PubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1977

Authors and Affiliations

  • J. S. StehlinJr.
  • B. C. Giovanella
  • P. D. de Ipolyi
  • L. R. Muenz
  • R. F. Anderson
  • A. A. Gutierrez

There are no affiliations available

Personalised recommendations