Abstract
Since many techniques in immunology, virology, biochemistry, and biophysics depend upon the availability of homogeneous populations of human tumor cells, the establishment of permanent homogeneous tumor cells lines is a useful approach in experimental human cancer research. However, the cultivation of human breast tumor cells remains a challenging problem. This paper presents our experience in growing these tumor cells in vitro.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
CAILLEAU, R.M.: Old and new problems in human tumor cell cultivation. In: Human Tumor Cells in vitro, Fogh, J. (ed.). New York: Plenum Press, Press, 1975, pp. 79–114.
DMOCHOWSKI, L., SEMAN, G., MYERS, B., GALLAGHER, H.: Relationship of viruses to the origin of the human breast cancer. An exploratory-study of the submicroscopic appearance of human breast cancer. Med. Rec. Ann. 61, 384–387 (1968).
FOGH, J., TREMPE, G.: New human tumor cell lines. In: Human Tumor Cells in vitro, Fogh, J. (ed.). New York: Plenum Press, 1975, pp. 115–159.
GIRALDO, G., BETH, E., HIRSHAUT, Y., AOKI, T., OLD, L., BOYCE, E., CHOPRA, H.: Human sarcomas in culture. Foci of altered cells and a common antigen; induction of foci and antigen in human fibroblast cultures by filtrates. J. exp. Med. 133, 454–478 (1971).
KIESTLING, A.: Personal communication, 1972.
KORSTEN, C.B., PERSIJN, J.P.: A simple assay for estrogen-binding capacity in human mammary tumors. Z. klin. Chem. klin. Biochem. 10, 502–508 (1972).
LASFARGUES, E., OZZELLO, L.: Cultivation of human breast carcinomas. J. nat. Cancer Inst. 21, 1131–1147 (1958).
LASFARGUES, E., COUTINHO, W., MOORE, D.: Pitfalls in the isolation of a human breast carcinoma virus in tissue culture, J. nat. Cancer Inst. 48, 1101–1105 (1972).
MURAD, T., SCARPELLI, D.: The ultrastucture of medullary and scirrhous mammary duct carcinoma. Amer. J. Path. 50, 335–360 (1967).
PLATA, E., AOKI, T., ROBERTSON, D., CHU, E., GERWIN, B.: An established cultured cell line (HBT-39) from human breast carcinoma, J. nat. Cancer Inst. 50, 849–862 (1973).
REED, M., GEY, G.: Cultivation of normal and malignant human lung-tissue. I. The establishment of three adenocarcinoma cell strains. Lab. Invest. II, 638–652 (1962).
TUMILOWICZ, J., SARKAR, N.: Accumulating filaments and other ultrastructural aspects of declining cell cultures derived from human breast tumors. Exp. molec. Path 16, 210–221 (1972).
YOUNG, R., CAILLEAU, R., MACHAY, B., REEVES, W.: Establishment of epithelial cell line MDA-MB-157 from metastatic pleural effusion of human breast carcinoma. in vitro 9, 239–245 (1974).
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1976 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Trempe, G.L. (1976). Human Breast Cancer in Culture. In: St-Arneault, G., Band, P., Israël, L. (eds) Breast Cancer. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 57. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81043-5_5
Download citation
DOI: https://doi.org/10.1007/978-3-642-81043-5_5
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81045-9
Online ISBN: 978-3-642-81043-5
eBook Packages: Springer Book Archive