Abstract
Compared to chemotherapy, immunotherapy is minimally toxic. It is not, however, a branch of homeopathy. We have seen that a contrary effect to the one sought can be obtained (tumour growth enhancement). Direct toxic effects, minor or severe and possibly lethal, have been observed. Thus the toxicology (MATHE, 1976; SCHWARZENBERG et al., 1976) of this new weapon in cancer treatment must be known.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
AMERY,W.: Lancet 1, 574 (1975).
BALDWIN, R.W., PIMM, M.V.: Nat. Cancer Inst. Monogr. 39, 11 (1973).
BORNSTEIN, R.S., MASTRANGELO, M.J., SULIT, H., GHEE, D., YARBO, J.W., PREHN. L., PREHN, R.T.: Nat. Cancer Inst. Monogr. 39, 213 (1973).
CORNELL, C.J. jr., SMITH, K.A., CORNWELL, G.G. III, GRACE, W.R., McINTYRE, O.R.: Proc. Amer. Assoc. Cancer Res. 16, 265 (abstract No. 1178) (1975).
COSTANZI, J., GAGLIANO, R., LOUKAS, D., SAKAI, H., THURMAN, G., HARRIS, N., GOLDSTEIN, A.: Proc. Amer. Assoc. Cancer Res. 16, 135 (abstract No. 537) (1975).
GEFFARD, M., ORBACH-ARBOUYS, S.: Cancer Immunol. Immunoth. 1, 41 (1976).
GORDON, B.L., EDYNAK, E.M.: Proc. Amer. Assoc. Cancer Res. 16, 123 (abstract No. 489) (1975).
HANNA, M.G. jr.: Seminars in Oncology 1, 319 (1974).
HERSH, E.M., REED, R.C., GUTTERMAN, J.U., MAVLIGIT, G.M., BURGESS, A.A.: Symposium International sur “Les Immunostimulants Bactériens, Structures Chimiques, Mécanismes d’Action, Applications”. Paris, Institut Pasteur, October 1974.
HIRSHAUT, Y., PINSKY, C., CUNNINGHAM-RUNDLES, W., RAO, B., FRIED, J., OETTGEN, H.: Proc. Amer. Assoc. Cancer Res. 16, 181 (abstract No. 721) (1975).
HOWARD, J.G., SCOTT, M.T., CHRISTIE, G.H.: p. 110 in “Immunopotentiation” (Ciba Foundation Symposium 18). 1 Vol., Amsterdam: Elsevier Excerpta Medica 1973.
HUNT, J.S., SPARKS, F.C., PILCH, Y.H., SILVERSTEIN, M.J., HASKELL, C.M., MORTON, D.L.: Lancet 2, 820 (1973).
ISRAEL, L., HALPERN, B.: Nouv. Presse Med. 1, 19 (1972).
JURCZYK-PROCYK, S., MARTIN, M., DUBOUCH, P., GHEORGHIU, M., ECONOMIDES, F., KHALIL, A., RAPPAPORT, H.: Cancer Immunol. Immunoth. 1, 55 (1976).
KHALIL, A., BOURUT, C., HALLE-PANNENKO, O., MATHE, G., RAPPAPORT, H.: Biomedicine 22, 112 (1975).
LEVY, N.L.: Nat. Cancer Inst. Monogr. 37, 85 (1973).
LEVY, N.L., MAHALEY, M.S. jr., DAY, E.D.: Int. J. Cancer 10, 244 (1972).
LOKICH, J.J.: Lancet 1, 331 (1975).
MacKHANN, C.F., HENDRICKSON, C.G., SPITLER, L.E., GUNNARSSON, A., BANERJEE, R., NELSON, W.R.: Cancer 35, 514 (1975).
MARAL, R., FLOC’H, F., JOUANNE, M., WERNER, G.H.: in “European Society of Toxicology”. Amsterdam: Excerpta Medica, in press (1976).
MATHE, G.: in “European Society of Toxicology”. Amsterdam: Exerpta Medica, in press (1976).
MATHE, G., AMIEL, J.L., SCHWARZENBERG, L., SCHNEIDER, M., HAYAT, M., VASSAL, F. DE, JASMIN, C., ROSENFELD, C., SAKOUHI, M., CHOAY, J.: Europ. J. Clin. Biol. Res. 15, 671 (1970).
MATHE, G., HALLE-PANNENKO, O., AMIEL, J.L.: p. 48 in “Corynebacterium parvum: application in Experimental and Clinical Oncology” New-York: Plenum press, 1975b.
MATHE, G., HALLE-PANNENKO, O., FLORENTIN, I., BRULEY-ROSSET, M., KAMEL, M., HIU, I.J., BOURUT, C.: Europ. J. Cancer 11, 801 (1975a).
MOERTEL, C.G., RITTS, R.E., SCHUTT, A.J., HAHN, R.G.: Proc. Amer. Assoc. Cancer Res. 16, 143 (abstract No. 569) (1975).
MOORE, M., LAWRENCE, N., WITHEROW, P.J.: Europ. J. Cancer 10, 673 (1974).
MOTTA, R.: Etude des antigènes de surface des cellules normales et leucémiques de souris et de leurs relations avec le système immunologique de l’hôte. Thesis, Université Paris V II, 1974.
MUGGLETON, P.W., PRINCE, G., HILTON, M.: Lancet 1, 1353 (1975).
PORTELANCE, V.: Colloque de Pédiatrie, Préventorium Calmette,Yerres, France, 1974.
QUEVILLON, M.: Cancer Immunol. Immunoth. in press (1976).
RICHMAN, S.P.: Proc. Amer. Assoc. Cancer Res. 16, 227 (abstract No. 1025) (1975).
ROBINSON, E., HAASZ, R., BARTAL, A., COHEN, Y.: 9th therapy, London (abstract C 82 ) July 1975.
ROSENBERG, E.B., KANNER, S.P., SCHWARTZMAN, R.J., COLSKY, J.: Arch. Intern. Med. 134, 769 (1974).
SCHAFER, L.A., WASHINGTON, M.L., GOLDSTEIN, A.L.: Proc. Amer. Assoc. Cancer Res. 16, 233 (abstract No. 1051) (1975).
SCHAUF, V., LANDAU, W., FALK, L.: Proc. Amer.Assoc. Cancer Res. 16, 102 (abstract No. 406) (1975).
SCHWARZENBERG, L., SIMMLER, M.C., PICO, J.L..Cancer Immul. Immunoth. 1, 69 (1976).
SCOTT, M.T., Cell. Immunol. 13, 251 (1974).
SERROU, B., MICHEL, H., DUBOIS, J.B., SERRE, A.: Biomedicine 23, 236 (1975).
SIMMLER, M.C., SCHWARZENBERG, L., MATHE, G.: Nouv. Presse Med. in press (1976a).
SIMMLER, M.C., SCHWARZENBERG, L., MATHE, G.: Cancer Immunol. Immunoth. in press (1976b).
SPARKS, F.C., SILVERSTEIN, M.J., HUNT, J.S., HASKELL, C.M., PILCH, Y.H., MORTON, D.L.: New England J. Med. 289, 827 (1973).
STEWART, T., TOLNAI, G.: Cancer 24, 117 (1969).
SUTER, E., MUNOZ, J.J.: Proc. Soc. Exp. Biol. Med. 114, 211 (1963).
SUTER, E., ULLMAN, G.E., HOFFMAN, R.G.: Proc. Soc. Exp. Biol. Med. 99, 167 (1958).
THOMAS, J.W., PLENDERLEITH, I.H., CLEMENTS, D., LANDI, S.: p. 315 in XIth International Cancer Congress, Florence, October 1974. Vol. 1, Conferences, Symposia workshops.
WEBSTER, D.J. T., HUGHES, L.E.: Lancet 1, 389 (1975).
WEISS, D.W.: Nat. Cancer Inst. Monogr. 35, 157 (1972).
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1976 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Mathé, G. (1976). Toxicology and Adverse Effects. In: Cancer Active Immunotherapy. Recent Results in Cancer Research, vol 55. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-81017-6_8
Download citation
DOI: https://doi.org/10.1007/978-3-642-81017-6_8
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-81019-0
Online ISBN: 978-3-642-81017-6
eBook Packages: Springer Book Archive