Postsynaptic Cell Characteristics Determining Membrane Potential Changes
The aim of this paper is to review and re-appraise some of the available experimental information concerning the mechanism by which excitatory and inhibitory synaptic transmitters, which are released from presynaptic terminals, evoke membrane potential changes in the postsynaptic cell. These transmitter-induced changes will in turn determine the possible further transmission of a signal, usually in the form of an action potential. Attention will be focussed on the motoneurone in the spinal cord of the cat as representative of a nerve cell in the vertebrate central nervous system. Information from other kinds of experimental material, especially the nerve-muscle preparation will also be considered, as it serves to elucidate processes occurring in the central neurone.
KeywordsMembrane Potential Synaptic Potential Membrane Potential Change Synaptic Region Endplate Potential
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