Histological Classification and its Implications in the Utility of Registry Data in Epidemiological Studies

  • E. Saxén
Part of the Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer book series (RECENTCANCER, volume 50)


The value of cancer registry data in epidemiological studies concerned with cancer is dependent upon the reliability and comparability of the data used. If these data are to be analyzed it is necessary for the material to have been processed with reference to uniform classification and coding systems.To a great extent, progress in science depends upon classification; a given material must be grouped and classified in accordance with fixed criteria if some order is to be obtained from chaos. The classification applied depends on the problem under investigation. However, if a classification system does not lead to logical and useful results it might be wrong, and trials with a new one are required. Currently, the basis of tumor classification is microscopy, which means that a histomorphological classification of tumors is employed.


Thyroid Cancer Thyroid Carcinoma Cancer Registry Basal Cell Carcinoma Papillary Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    BAREKAT, A. A., SAIDI, F., DUTZ, W.: Cancer survey in south Iran with special reference to gastrointestinal neoplasms. Int. J. Cancer 7, 353 (1971).PubMedCrossRefGoogle Scholar
  2. 2.
    Cancer Problems 160 years ago. Int. J. Cancer 2, 281 (1967).Google Scholar
  3. 3.
    CUTLER, S. J., BLACK, M. M., FRIEDELL, G. H., VIDONE, R. A., GOLDENBERG, I. S.: Prognostic factors in cancer of the female breast. II. Reproducibility of histopathologic classification. Cancer 19, 75 (1966).PubMedCrossRefGoogle Scholar
  4. 4.
    FAULKNER, J. W., DOCKERTY, M. E.: Lymphosarcoma of the small intestine. Surg Gynec. Obstet. 95, 76 (1952).PubMedGoogle Scholar
  5. 5.
    FEINSTEIN, A. R., GOLFMAN, N. A., YESNER, R.: Observer variability in the histopathologic diagnosis of lung cancer. Ann. Rev. resp. Dis. 101, 671 (1970).Google Scholar
  6. 6.
    Finnish Cancer Registry: Cancer Incidence in Finland 1969. Helsinki: Cancer Society of Finland (publ. no. 18) 1972.Google Scholar
  7. 7.
    FRANSSILA, K.: Value of histologic classification of thyroid cancer. Acta path. microbiol. scand. Suppl. 225 (1971).Google Scholar
  8. 8.
    FRANSSILA, K., SAXéN, E.: Histologic classification as a problem in the epidemiology of thyroid cancer. In: Recent Results in Cancer Research. Vol. 39. Ed. E. Grundmann, H. Tulinius, Berlin-Heidelberg-New York: Springer 1972.Google Scholar
  9. 9.
    HAKAMA, M., FRANSSILA, K., SAXéN, E.: Reliability of frequency figures for malignant lymphomas. Ann. clin. Res. 1973. In press.Google Scholar
  10. 10.
    HARBITZ, T. B., HAUGEN, O. A.: Histology of the prostate in elderly men. Acta path. microbiol. scand. A 80, 756 (1972).Google Scholar
  11. 11.
    LARSSON, S.: Completeness and reliability of lung cancer registration in the Swedish Cancer Registry. Acta path. microbiol. scand. A 79, 389 (1971).Google Scholar
  12. 12.
    MUIR, C. S.: Nasopharyngeal carcinoma in non-Chinese populations with special reference to South-east Asia and Africa. Int. J. Cancer 8, 351 (1971).PubMedGoogle Scholar
  13. 13.
    SAKSELA, E., MEYER, B.: Cell-mediated cytoxicity against HeLa cells in patients with invasive and preinvasive cervical cancer. J. nat. Cancer Institute 1973. In press.Google Scholar
  14. 14.
    SAKSELA, E., RINTALA, A.: Misdiagnosis of prepubertal malignant melanoma. Reclassification of a cancer registry material. Cancer 22, 1308 (1968).PubMedCrossRefGoogle Scholar
  15. 15.
    SAXÉN, E., FRANSSILA, K., HAKAMA, M.: Effect of histological typing of registry material on the results of epidemiological comparison in thyroid cancer. In: Thyroid Cancer. UICC Monograph Series Vol. 12. Ed. C. Hedinger, p.98. Berlin-Heidelberg-New York: Springer 1970.Google Scholar
  16. 16.
    WAHI, P. N.: Malignant tumors of the nasopharynx and accessory sinuses in India. In: Cancer of the Nasopharynx. UICC Monograph Series Vol. 1, p.24. Copenhagen: Munksgaard 1967.Google Scholar
  17. 17.
    VIRCHOW, R.: Die Vorlesungen Rudolf Virchows über Allgemeine Pathologische Anatomie. Ed. E. Kugler. Jena: Gustav Fischer 1930.Google Scholar
  18. 18.
    VUORI, J.: Primary malignant tumors of the small intestine diagnosed in Finland 1953–1962 (in Finnish). Thesis, University of Turku 1970.Google Scholar
  19. 19.
    YEH, S.: Histology of nasopharyngeal cancer. In: Cancer of the Nasopharynx. UICC Monograph Series Vol. 1, p. 147. Copenhagen: Munksgaard 1967.Google Scholar

Copyright information

© Springer-Verlag Berlin · Heidelberg 1975

Authors and Affiliations

  • E. Saxén

There are no affiliations available

Personalised recommendations