Summary
Hodgkin’s disease is primarily a disease of the lymphatic system. It may be unicentric from the beginning and then spread at first locally in the lymphatic system. Spread via the blood-stream seems to be more frequent with advancing disease, but may occur early. Direct overgrowth to extranodal sites may occur early in the course of the disease.
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Landberg, T. (1974). Presentation and Progression of Hodgkin’s Disease. In: Musshoff, K. (eds) Diagnosis and Therapy of Malignant Lymphoma. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 46. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80829-6_25
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DOI: https://doi.org/10.1007/978-3-642-80829-6_25
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