Analyse von stabil-isotop markierten Verbindungen

  • H.-L. Schmidt
Part of the Anwendung von Isotopen in der Organischen Chemie und Biochemie book series (ISOTOPEN, volume 2)

Zusammenfassung

Massenspektrometrie und Emissions-Spektralanalyse führten zur Entdeckung der stabilen Isotope der Elemente Wasserstoff, Kohlenstoff, Stickstoff, Sauerstoff und Chlor; die beiden Methoden zählen auch heute noch zu den wichtigsten Verfahren für die Bestimmung dieser Isotope. Die Chlor-Isotope 35Cl und 37Cl wurden 1919 von Aston [1] massenspektrographisch nachgewiesen; durch Emissions-Spektralanalyse fanden 1927 King und Birge 13C [2], Naudé 1929 15N [3] und Giauque und Johnston im gleichen Jahr 17O und 18O [4]. 2H wurde 1932 mit der gleichen Methode von Urey et al. entdeckt [5]; die bald darauf entwickelten gravimetrischen Deuterium-Mikrobestimmungen (1935 Vogt und Hamilton »Fallender Tropfen« [6] und 1938 Linderstrøm-Lang et al. »Schwebender Tropfen« [7]) ermöglichten eine schnelle Zunahme der Tracer-Untersuchungen mit schwerem Wasserstoff.

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1974

Authors and Affiliations

  • H.-L. Schmidt
    • 1
  1. 1.Institut für Chemie und landwirtschaftliche Technologie WeihenstephanTechnische Universität MünchenDeutschland

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