Chromosome Aneuploidy in Human Malignancies: Effusions

  • Peo C. Koller
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 38)


Cytological studies of experimental ascitic tumours in mice and rats have shown that free cells in the peritoneal fluid provide very suitable material for chromosome analyses, and their behaviour can be manipulated in experiments. Furthermore, it was observed that the ascitic fluid represents an environment in which malignant cells are independent, and can express unhindered their potentialities as regards proliferation and chromosome variability. The cytological findings in ascites tumours of animals stimulated similar studies into the effusions of cancer patients.


Modal Number Ascitic Fluid Chromosome Constitution Chromosome Aneuploidy Malignant Effusion 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1972

Authors and Affiliations

  • Peo C. Koller
    • 1
  1. 1.University of LondonUK

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