Chromosomal and Functional Differences in Malignant Cell Populations

  • Peo C. Koller
Part of the Recent Results in Cancer Research book series (RECENTCANCER, volume 38)


Biologists have put forward the view that the heterogeneous population structure of tumours enhances their progression. The chromosome variants in a tumour represent a pool of cell types with altered genotypes which confer certain advantages in a changing environment. Many studies have been carried out attempting to clarify the possible relationship between certain characteristics of tumours and chromosome patterns representing a particular genotype. Some of the findings from such studies are described below.


Chromosome Number Modal Number Marker Chromosome Chromosome Constitution Polyploid Cell 
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Copyright information

© Springer-Verlag Berlin · Heidelberg 1972

Authors and Affiliations

  • Peo C. Koller
    • 1
  1. 1.University of LondonUK

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