Mitotic Anomalies in Tumours and Boveri’s Theory
- 30 Downloads
The growth of cancerous tissue depends on cell multiplication, and the process by which cancer cells multiply had already drawn the attention of pathologists in the last century. Arnold (1879) was the first to describe cell division in human tumours, and cells which he saw containing several nuclei suggested to him that they were produced by “multiple” division of the nucleus. The term “chromosome” was only a year old when Klebs (1889) described aberrant mitosis in tumour tissue, and noted that in some cells the number of “chromosome bodies” was very large.
KeywordsDaughter Nucleus Chromosome Constitution Ascites Tumour Cellular Heterogeneity Dicentric Chromosome
Unable to display preview. Download preview PDF.