Abstract
The stimulant action of human semen (0.25–1 ml) on the nonpregnant uterus when introduced into the vagina or uterine lumen was reported by Karlson (1959). Increased motility of the body of the uterus was accompanied by decreased motility of the cervix, pressure measurements being made by a method in which transducers are inserted into the fundus, isthmus and cervix. In the light of subsequent investigations it is almost certain that these effects can be attributed to the presence of prostaglandins in semen.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Adamson, U., Eliasson, R., Wiklund, B.: Tachyphylaxis in rat uterus to some prostaglandins. Acta physiol. scand. 70, 451–452 (1967).
Asplund, J.: Some preliminary experiments in connection with the effect of prostaglandin on the uterus and tubae in vivo. Acta physiol. scand. 13, 109–114 (1947).
Beazley, J. M., Dewhurst, C. J., Gillespie, A.: Induction of labour with prostaglandin E2. J. Obstet. Gynaec. Brit. Commonw. 77, 193–199 (1970).
Bergström, S., Eliasson, R., von Euler, U. S., Sjövall, J.: Some biological effects of two crystalline prostaglandin factors. Acta physiol. scand. 45, 133–144 (1959).
Berti, F., Naimzada, M.: Spiccata attività della prostaglandina E1 (PGE1) sulp utero di cavia. Boll Soc. ital. Biol. sper. 41, 1324–1326 (1965).
Bygdeman, M.: The effect of different prostaglandins on the human myometrium in vitro. Acta physiol. scand. 63, suppl. 242, 1–78 (1964).
Bygdeman, M.: Studies of the effects of prostaglandins in seminal plasma on human myometrium in vitro. Nobel Symposium 2, Prostaglandins. Eds.: S. Bergström and B. Samuelsson. Stockholm: Almqvist and Wiksell 1967, pp. 71–77.
Bygdeman, M., Hamberg, M.: The effect of eight new prostaglandins on human myometrium. Acta physiol. scand. 69, 320–326 (1967).
Bygdeman, M., Hamberg, M., Samuelsson, B.: The content of different prostaglandins in human seminal fluid and their threshold doses on the human myometrium. Mem. Soc. Endocr. 14, 49–64 (1966).
Bygdeman, M., Kwon, S. U., Mukherjee, T., Roth-Brandel, U., Wiqvist, N.: The effect of the prostaglandin F compounds on the contractility of the pregnant human uterus. Amer. J. Obstet Gynec. 106, 567–572 (1970).
Bygdeman, M., Kwon, S. U., Mukherjee, T., Wiqvist, N.: Effect of intravenous infusion of prostaglandin E1 and E2 on motility of the pregnant human uterus. Amer. J. Obstet. Gynec. 102, 317–326 (1968).
Bygdeman, M., Kwon, S. U., Wiqvist, N.: The effect of prostaglandin E1 on human pregnant myometrium in vivo. Nobel Symposium 2, Prostaglandins. Eds.: S. Bergström and B. Samuelsson. Stockholm: Almqvist and Wiksell 1967, pp. 93–96.
Bygdeman, M., Wiqvist, N.: Early abortion in the human. Ann. N. Y. Acad. Sci. 180, 473–482 (1971).
Clegg, P. C., Hall, W. J., Pickles, V. R.: The action of ketonic prostaglandins on the guinea pig myometrium. J. Physiol. (Lond.) 183, 123–144 (1966).
Eliasson, R.: The effect of different prostaglandins on the motility of the human myometrium. Mem. Soc. Endocr. 14, 77–88 (1966).
Eliasson, R., Brzdekiewicz, Z., Wiklund, B.: Tachyphylactic response of the isolated rat myometrium to prostaglandins E. In: Prostaglandins, Peptides and Amines. Eds.: P. Mantegazza and E. W. Horton. London: Academic Press 1969, pp. 57–64.
Eliasson, R., Posse, N.: The effect of prostaglandin on the non-pregnant human uterus in vivo. Acta obstet. gynec. scand. 39, 112–126 (1960).
Eliasson, R., Posse, N.: Rubin’s test before and after intravaginal application of prostaglandin. Int. J. Fert. 10, 373–377 (1965).
Embrey, M. P.: The effect of prostaglandins on the human pregnant uterus. J. Obstet. Gynaec. Brit. Commonw. 76, 783–789 (1969).
Embrey, M. P.: Induction of labour by prostaglandins E1 and E2. Brit. med. J. 2, 256–258 (1970 a).
Embrey, M. P.: Induction of abortion by prostaglandins E1 and E2. Brit. med. J. 2, 258–260 (1970 b).
Embrey, M. P., Morrison, D. L.: The effect of prostaglandins on human pregnant myometrium in vitro. J. Obstet. Gynaec. Brit. Commonw. 75, 829–832 (1968).
Hawkins, R. A., Jessup, R., Ramwell, P. W.: Effect of ovarian hormones on response of the isolated rat uterus to prostaglandins. Prostaglandin Symposium of the Worcester Foundation for Exp. Biol. Eds.: P. W. Ramwell and J. E. Shaw. New York: Interscience 1968, p. 11–19.
Horton, E. W.: Action of prostaglandin E1 on tissues which respond to bradykinin. Nature 200, 892–893 (1963).
Horton, E. W., Main, I. H. M.: A comparison of the biological activities of four prostaglandins. Brit. J. Pharmac. 21, 182–189 (1963).
Horton, E. W., Main, I. H. M.: A comparison of the actions of prostaglandins F2α and E1 on smooth muscle. Brit. J. Pharmac. 24, 470–476 (1965).
Horton, E. W., Main, I. H. M.: The relationship between the chemical structure of prostaglandins and their biological activity. Mem. Soc. Endocr. 14, 29–37 (1966).
Horton, E. W., Main, I. H. M., Thompson, C. J.: Effects of prostaglandins on the oviduct, studied in rabbits and ewes. J. Physiol. (Lond.) 180, 514–528 (1965).
Karim, S. M. M.: Identification of prostaglandins in human amniotic fluid. J. Obstet. Gynaec. Brit. Commonw. 73, 903–908 (1966).
Karim, S. M. M.: The identification of prostaglandins in human umbilical cord. Brit. J. Pharmac. 29, 230–237 (1967).
Karim, S. M. M.: Appearance of prostaglandin F2α in human blood during labour. Brit. med. J. 4, 618–621 (1968).
Karim, S. M. M.: The role of prostaglandin F2α in parturition. In: Prostaglandins, Peptides and Amines. Eds.: P. Mantegazza and E. W. Horton. London: Academic Press 1969, pp. 65–72.
Karim, S. M. M.: Action of prostaglandins in the pregnant woman. Ann. N. Y. Acad. Sci. 180, 483–498 (1971).
Karim, S. M. M., Devlin, J.: Prostaglandin content of amniotic fluid during pregnancy and labour. J. Obstet. Gynaec. Brit. Commonw. 74, 230–234 (1967).
Karim, S. M. M., Filshie, G. M.: Therapeutic abortion using prostaglandin F2α. Lancet 1, 157–159 (1970 a).
Karim, S. M. M., Filshie, G. M.: Use of prostaglandin E2 for therapeutic abortion. Brit. med. J. 3, 198–200 (1970 b).
Karim, S. M. M., Hillier, K., Trussell, R. R., Patel, R. C., Tamusange, S.: Induction of labour with prostaglandin E2. J. Obstet. Gynaec. Brit. Commonw. 77, 200–210 (1970).
Karim, S. M. M., Trussell, R. R., Hillier, K., Patel, R. C.: Induction of labour with prostaglandin F2α . J. Obstet. Gynaec. Brit. Commonw. 76, 769–782 (1969).
Karim, S. M. M., Trussell, R. R., Patel, R. C., Hillier, K.: Response of pregnant human uterus to prostaglandin F2α-induction of labour. Brit. med. J. 4, 621–623 (1968).
Karlson, S.: The influence of seminal fluid on the motility of the nonpregnant human uterus. Acta obstet. gynec. scand. 38, 503–521 (1959).
Roth-Brandel, U., Bygdeman, M., Wiqvist, N., Bergström, S.: Prostaglandins for induction of therapeutic abortion. Lancet. 1, 190–191 (1970).
Sandberg, F., Ingelman-Sundberg, A., Rydén, G.: The effect of prostaglandin E1 on the human uterus and the fallopian tubes in vitro. Acta obstet. gynec. scand. 42, 269–278 (1963).
Sandberg, F., Ingelman-Sundberg, A., Rydén, G.: The effect of prostaglandin E2 and E3 on the human uterus and fallopian tubes in vitro. Acta obstet. gynec. scand. 43, 95–102 (1964).
Sandberg, F., Ingelman-Sundberg, A., Rydén, G.: The effect of prostaglandin F1 α, B1 β, F2 α and F2 β, on the human uterus and the fallopian tubes in vitro. Acta obstet. gynec. scand. 44, 585–594 (1965).
Sandberg, F., Ingelman-Sundberg, A., Rydén, G., Joelsson, I.: The absorption of tritium-labelled prostaglandin E1 from the vagina of non-pregnant women. Acta obstet. gynec. scand. 47, 22–26 (1968).
Sullivan, T. J.: Response of the mammalian uterus to prostaglandins under differing hormonal conditions. Brit. J. Pharmac. 26, 678–685 (1966).
Wiqvist, N., Bygdeman, M.: Induction of therapeutic abortion with intravenous prostaglandin F2α. Lancet. 1, 889 (1970).
Wiqvist, N., Bygdeman, M., Kwon, S. U., Mukherjee, T., Roth-Brandel, U.: Effect of prostaglandin E1 on the midpregnant human uterus. Amer. J. Obstet. Gynecol. 102, 327–332 (1968).
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1972 Springer-Verlag Berlin · Heidelberg
About this chapter
Cite this chapter
Horton, E.W. (1972). Female Reproductive Tract Smooth Muscle. In: Prostaglandins. Monographs on Endocrinology, vol 7. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80642-1_6
Download citation
DOI: https://doi.org/10.1007/978-3-642-80642-1_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-80644-5
Online ISBN: 978-3-642-80642-1
eBook Packages: Springer Book Archive