Synthesis

  • Eric William Horton
Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 7)

Abstract

Total chemical synthesis of all the major natural prostaglandins is now possible as a result of the elegant methods devised by E. J. Corey. The synthesis illustrated in Fig. 1 gives high yields of the prostaglandins in their natural stereochemical configuration and may prove commercially feasible for large scale production.

Keywords

Boron Sodium Hydroxide Prostaglandin Palladium Nitrile 

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1972

Authors and Affiliations

  • Eric William Horton
    • 1
  1. 1.Department of PharmacologyUniversity of EdinburghEdinburghGreat Britain

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