Prostaglandins pp 154-156 | Cite as

Urinary System

  • Eric William Horton
Part of the Monographs on Endocrinology book series (ENDOCRINOLOGY, volume 7)

Abstract

The increase in water permeability of the toad bladder produced by vasopressin is inhibited by PGE1 (Orloff, Handler and Bergström, 1965). Similar anti-vasopressin actions of PGE1 have been observed on the rabbit collecting tubule (Orloff and Grantham, 1967). Since these effects of vasopressin are known to be mediated by cyclic AMP, which is not inhibited by PGE1, it is likely that PGE1 acts by inhibiting adenyl cyclase.

Keywords

Permeability Filtration Adenosine Prostaglandin PGE1 

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References

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Copyright information

© Springer-Verlag Berlin · Heidelberg 1972

Authors and Affiliations

  • Eric William Horton
    • 1
  1. 1.Department of PharmacologyUniversity of EdinburghEdinburghGreat Britain

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