Summary
Male Wistar rats were fed an isocaloric sucrose, starch and fat-rich diet, Arginine was given 0.5 g/kg, p/o and 50 mM on perfusion of the isolated rat pancreas. Insulin and glucagon were measured immunologically. Sucrose-fed rats showed in vivo a significant increase of insulin release and a prolonged hypoglycemia up to 45 min. On perfusion, arginine induced a biphasic insulin and glucagon release, much higher in sucrose-fed rats then in controls.
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Laube, H. et al. (1970). Arginin-induzierte Sekretion von Insulin und Glucagon bei verschiedenen Diätformen. In: Kracht, J. (eds) Endokrinologie der Entwicklung und Reifung. Symposion der Deutschen Gesellschaft für Endokrinologie in Ulm vom 26.—28. Februar 1970, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80591-2_88
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DOI: https://doi.org/10.1007/978-3-642-80591-2_88
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