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Arginin-induzierte Sekretion von Insulin und Glucagon bei verschiedenen Diätformen

  • H. Laube
  • R. Fussgänger
  • R. Goberna
  • K. Schröder
  • M. Hinz
  • K. Straub
  • E. F. Pfeiffer
Part of the Symposion der Deutschen Gesellschaft für Endokrinologie in Ulm vom 26.—28. Februar 1970 book series (ENDOKRINOLOGIE, volume 16)

Arginine Induced Secretion of Insulin and Glucagon in Rats, Kept on Various Diets

Summary

Male Wistar rats were fed an isocaloric sucrose, starch and fat-rich diet, Arginine was given 0.5 g/kg, p/o and 50 mM on perfusion of the isolated rat pancreas. Insulin and glucagon were measured immunologically. Sucrose-fed rats showed in vivo a significant increase of insulin release and a prolonged hypoglycemia up to 45 min. On perfusion, arginine induced a biphasic insulin and glucagon release, much higher in sucrose-fed rats then in controls.

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Copyright information

© Springer-Verlag Berlin Heidelberg New York 1970

Authors and Affiliations

  • H. Laube
    • 1
  • R. Fussgänger
    • 1
  • R. Goberna
    • 1
  • K. Schröder
    • 1
  • M. Hinz
    • 1
  • K. Straub
    • 1
  • E. F. Pfeiffer
    • 1
  1. 1.Department für Endokrinologie und Stoffwechsel, Zentrum für Innere Medizin und KinderheilkundeUniversität UlmDeutschland

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