Summary
Radioimmunoassay is specific and sufficiently sensitive to detect ng or pg amounts of peptide hormones. “Results” are easily obtained, but for a correct interpretation the following points have to be considered: Immunological reactivity of the labelled hormone, behaviour of damaged hormone and free iodine in the separation system used, standardisation of antibody and reference preparation of the hormone, non-specific factors interfering with the antigen-antibody reaction. Several dilutions of the unknown should always be assayed in order to control the specificity of the reaction.
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Literatur
Greenwood, F. C.; In: “Modern Trends in Endocrinology”, series 3, pp 288–322 Ed. H. Gardiner-Hill, London: Butterworth 1967.
Berson, S. A., Yalow, R. S.: In “Clinical Endocrinology””II pp 699–720 Ed. E. B. Astwood and C. E. Cassidy, New York: Grune and Stratton 1968.
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Girard, J., Baumann, J.B., Nars, P.W., Vest, M. (1970). Probleme der radioimmunologischen Eiweißhormonbestimmung. In: Kracht, J. (eds) Endokrinologie der Entwicklung und Reifung. Symposion der Deutschen Gesellschaft für Endokrinologie in Ulm vom 26.—28. Februar 1970, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80591-2_62
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DOI: https://doi.org/10.1007/978-3-642-80591-2_62
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