Summary
The basal metabolic rate of the guinea pig decreases continously during pregnancy. The BMR of the fetus amounts to 75% of that found in the mothers. By measuring the free Ti4 levels in plasma, an explanation for these differences of the metabolic rates of mothers and fetuses was expected. There were no differences in the serum concentration of total T4 and AFT4 in the pregnant, non-pregnant or male adult animal. The same value for total T4 as in adults was found in the fetus; on the other hand, the percentual free T4- as well as the AFT4-value were twice that of the mothers, i.e.: no correlation could be found between BMR and the concentration of free T4. The metabolic significance of the considerably increased fetal AFT4-value is discussed.
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Literatur
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Herrmann, J., Krüskemper, H.L., Künzel, W., Moll, W., Müller, H. (1970). Ruheumsatz und freies Serumthyroxin bei graviden Meerschweinchen und Feten. In: Kracht, J. (eds) Endokrinologie der Entwicklung und Reifung. Symposion der Deutschen Gesellschaft für Endokrinologie in Ulm vom 26.—28. Februar 1970, vol 16. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80591-2_40
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DOI: https://doi.org/10.1007/978-3-642-80591-2_40
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