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Betablocker-Therapie der Glaukome

  • Conference paper
Medikamentöse Glaukomtherapie

Zusammenfassung

Noch nie hat eine Medikamentengruppe in der Pharmakotherapie des Glaukoms in so kurzer Zeit, in so breitem Umfang bei Patienten und Therapeuten Anerkennung gefunden wie die Betablocker. In einer Vielzahl klinischer und wissenschaftlicher Mitteilungen wurden die Vorzüge dieser Medikamentengruppe gegenüber den traditionellen Antiglaukomatosa hervorgehoben und die vorzügliche Wirksamkeit gerühmt. Das einfache Therapieschema mit einer nur zweimal täglichen Anwendung und das scheinbare Fehlen von lästigen Nebenwirkungen sorgte für eine rasche und gute Annahme dieses Therapiekonzeptes durch den Patienten. Erst mit einer gewissen Latenzzeit wurde man sich auch der Risiken und Nebenwirkungen der Betablocker-Therapie der Glaukome bewußt und gestand Einschränkungen der Anwendbarkeit bei bestimmten Patienten nur zögernd ein.

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Literatur

  1. Zimmermann TJ, Kaufman HE (1977) Timolol. Dose-response and duration of action. Arch Ophthalmol 95:605–607

    Article  Google Scholar 

  2. Zimmerman TJ, Kaufman HE (1977) Timolol. A ß-adrenergic blocking agent for the treatment of glaucoma. Arch Ophthalmol 95:601–604

    Article  PubMed  CAS  Google Scholar 

  3. Diamond GR, Werblin TP, Richter R, Radius R, Pollack P, Maumenee AE (1979) Extended clinical studies using timolol in patients with ocular hypertension and chronic open-angle glaucoma. Glaucoma 1:63–68

    Google Scholar 

  4. Skimoto G, Une H, Ohba N (1979) Effects of topically applied bupranolol on the intraocular pressure. Ophthalmologica 179: 214–219

    Article  Google Scholar 

  5. Oye van R, Sutter de E, Bie de S (1980) The effect of timolol maleate on the fellow eye. Bull Soc Belge Ophthalmol 191:69–74

    Google Scholar 

  6. Soll DB (1980) Evaluation of timolol in chronic open-angle glaucoma. Arch Ophthalmol 98:2178–2181

    Article  PubMed  CAS  Google Scholar 

  7. Nielsen NV, Eriksen JS (1981) Timolol and metoprolol. A diural study of the ocular and systemic effects in glaucoma patients. Acta Ophthalmol (Copenh) 59:517–525

    CAS  Google Scholar 

  8. Zimmerman TJ, Kass MA, Yablonski ME, Becker B (1979) Timolol maleate. Efficacy and safety. Arch Ophthalmol 97:656–658

    Article  PubMed  CAS  Google Scholar 

  9. Nielsen NV, Eriksen JS (1979) Timolol in maintenance treatment of ocular hypertension and glaucoma. Acta Ophthalmol (Copenh) 57:1070–1077

    Article  CAS  Google Scholar 

  10. Aasved H, Seland JH, Slagsvold JE (1979) Timolol maleate in treatment of open angle glaucoma. Acta Ophthalmol (Copenh) 57:700–708

    Article  CAS  Google Scholar 

  11. Dausch D, Michelson W (1979) Die Langzeitbehandlung des Weitwinkelglaukoms mit Timolol. Klin Monatsbl Augenheilkd 174: 127–135

    PubMed  CAS  Google Scholar 

  12. Boger WP, Puliafito CA, Steinert RF, Langston DP (1978) Longterm experience with timolol Ophthalmic solution in patients with open-angle glaucoma. Ophth AAO 85:259–267

    Google Scholar 

  13. Zimmerman TJ, Canale P (1979) Timolol-further observations. Ophth AAO 86:166–169

    CAS  Google Scholar 

  14. Smith RJ, Nagasubramanian A, Watkins R, Poinoosavmy D (1980) Addition of timolol maleate to routine medical therapy: a clinical trial. Br J Ophthalmol 64:779–781

    Article  PubMed  CAS  Google Scholar 

  15. Krieglstein GK (1978) Zur Tachyphylaxie von Beta-Rezeptorenblockern am Glaukomauge. Ber Zusammenkunft Dtsch Ophthalmol Ges 75:357

    PubMed  Google Scholar 

  16. Oksala A, Salminen L (1980) Zur Tachyphylaxie bei Timololbehandlung des chronischen Glaukoms. Klin Monatsbl Augen-heilkd 177:451–454

    Article  CAS  Google Scholar 

  17. Krieglstein GK (1979) Langzeituntersuchungen zur augendrucksenkenden Wirkung von Timolol-Augentropfen. Klin Monatsbl Augenheilkd 175:627

    PubMed  CAS  Google Scholar 

  18. Krieglstein GK (1979) Response of the intraocular pressure to various β-blocking agents. In: Krieglstein GK, Leydhecker W (eds), Glaucoma update. Springer, Berlin Heidelberg New York

    Chapter  Google Scholar 

  19. Krieglstein GK (1980) Timolol: Acute versus chronic intraocular pressure responses. Research and Clinical Forums 2:189

    Google Scholar 

  20. Krieglstein GK (1980) Betablocker therapy for glaucoma. In: Perspectives on current claucoma therapy. Excerpta Medica, Princeton

    Google Scholar 

  21. Krieglstein GK (1981) The long-term ocular and systemic effects of topically applied. metoprolol tartrate in glaucoma and ocular hypertension. Acta Ophthalmol (Copenh) 59:15

    Article  CAS  Google Scholar 

  22. Ros FE, Dake CL, Nagelkerke NJD, Greve EL (1978) Metoprolol eye drops in the treatment of glaucoma. A double-blind single-dose trial of a beta-adrenergic blocking drug. Albrecht Von Graefes Arch Klin Exp Ophthalmol 206:247–254

    Article  PubMed  CAS  Google Scholar 

  23. Sterk CC (1979) Atenolol 4% eyedrops in glaucoma simplex. Doc Ophthalmol 48:309–314

    Article  Google Scholar 

  24. Krieglstein GK (1978) Die Wirkung von Timolol-Augentropfen auf den Augeninnendruck von Glaucoma simplex. Klin Monatsbl Augenheilkd 172:75

    Google Scholar 

  25. Ober M, Scharrer A (1979) Timolol und Para-sympathicomimetica bei der Behandlung des erhöhten intraocularen Druckes. Albrecht Von Graefes Arch Klin Exp Ophthalmol 211:59–66

    Article  PubMed  CAS  Google Scholar 

  26. Ober M, Meythaler H, Porkert K (1979) Klinische Erfahrungen mit Timolol-Augentropfen. Ophthalmologica 178:204–209

    Article  PubMed  CAS  Google Scholar 

  27. Bischoff P. (1980) Langzeitresultate mit Timolol. Klin Monatsbl Augenheilkd 176: 551–554

    Article  PubMed  CAS  Google Scholar 

  28. Urner-Block U, Bischoff P (1981) Langzeitbehandlung mit Timolol über drei Jahre. Klin Monatsbl Augenheilkd 179:45–47

    Article  Google Scholar 

  29. Zimmerman TJ (1979) Timolol: Short term „escape“ and long term „drift“. Ann Ophthalmol 11:1239–1242

    Google Scholar 

  30. Steinert RF, Thomas J, Boger WP (1981) Long-term drift and continued effecaca after multiyear timolol therapy. Arch Ophthalmol 99:100–103

    Article  PubMed  CAS  Google Scholar 

  31. Krieglstein GK, Sould-Darseff J, Leydhecker W (1977) The intraocular pressure response of glaucomatous eyes to topically applied bupranolol. A pilot study. Albrecht Von Graefes Arch Klin Exp Ophthalmol 202:81–86

    Article  PubMed  CAS  Google Scholar 

  32. Calissendorff B, Marén N, Wettrell K, Östberg A (1980) Timolol versus pilocarpine separately or combined with acetazolamid-effects on intraocular pressure. Acta Ophthalmol (Copenh) 58:624–631

    Article  CAS  Google Scholar 

  33. Merkle W (1981) Timolol in Kombination mit anderen Antiglaucomatosa. Klin Monatsbl Augenheilkd 178:50–54

    Article  PubMed  CAS  Google Scholar 

  34. Airaksinen PJ (1979) The long-term hypotensive effects of timolol maleate compared with the effect of pilocarpine in simple and capsular glaucoma. Acta Ophthalmol (Copenh) 57:425–434

    Article  CAS  Google Scholar 

  35. Schiffer HP (1979) Vergleich zwischen Timolol und Pilocarpin bei der Behandlung des Weitwinkelglaukoms. Klin Monatsbl Augenheilkd 175:91–94

    PubMed  CAS  Google Scholar 

  36. Merté HJ, Merkle W (1980) Ergebnisse einer Doppelblindstudie mit verschiedenen Konzentrationen von Pilocarpin und Timolol zur Glaukombehandlung. Klin Monatsbl Augenheilkd 177:443–450

    Article  PubMed  Google Scholar 

  37. Hass I, Drance SM (1980) Comparison between pilocarpine and timolol on diurnal pressures in open-angle glaucoma. Arch Ophthalmol 98:480–481

    Article  PubMed  CAS  Google Scholar 

  38. Wettrell K (1977) Intraocular pressure reduction during treatment with pilocarpine and systemic propranolol. A comparative double-masked study. Albrecht Von Graefes Arch Klin Exp Ophthalmol 204:1–7

    Article  PubMed  CAS  Google Scholar 

  39. Keates EU, Stone RA (1981) Safety and effectiveness of concomitant administration of dipivefrin and timolol maleate. Am J Ophthalmol 91:243–248

    PubMed  CAS  Google Scholar 

  40. Ober M, Scharrer A (1980) Timolol und Adrenalindipivalat bei der Behandlung des erhöhten intraocularen Druckes. Albrecht Von Graefes Arch Klin Exp Ophthalmol 213:273–281

    Article  PubMed  CAS  Google Scholar 

  41. Öhrström A, Kättsträm Ö (1981) Interaction of timolol and adrenaline. Br J Ophthalmol 65:53–55

    Article  PubMed  Google Scholar 

  42. Phillips CI, Gore SM, Gunn PM (1978) Atenolol versus adrenaline eye drops and an evaluation of these two combined. Br J Ophthalmol 62:296–301

    Article  PubMed  CAS  Google Scholar 

  43. Thomas JV, Epstein DL (1981) Timolol and epinephrine in primary open angle glaucoma. Arch Ophthalmol 99:91–95

    Article  PubMed  CAS  Google Scholar 

  44. Öhrström A, Pandolfi M (1980) Regulation of intraocular pressure and pupil size by β-blokkers and epinephrine. Arch Ophthalmol 98:2182–2184

    Article  PubMed  Google Scholar 

  45. Öhrström A (1981) Dose-related interaction between timolol and adrenaline. Albrecht Von Graefes Arch Klin Exp Ophthalmol 216: 55–59

    Article  PubMed  Google Scholar 

  46. Sonntag JR, Brindley GO, Shields MB, Arafat NIT, Phelps CD (1979) Timolol and epinephrine. Comparison of effecacy and side effects. Arch Ophthalmol 97:273–277

    Article  PubMed  CAS  Google Scholar 

  47. Moss AP, Ritch R, Hargett NA, Kohn AN, Smith H, Podos SM (1978) A comparison of the effects of timolol and epinephrine on intraocular pressure. Am J Ophthalmol 86: 489–495

    PubMed  CAS  Google Scholar 

  48. Mc Donald MJ, Gore SM, Cullen PM, Phillips CI (1977) Comparison of ocular hypotensive effects of acetazolamide and atenolol. Br J Ophthalmol 61:345–348

    Article  Google Scholar 

  49. Scharrer A, Ober M (1979) Timolol und Acetazolamid bei der Behandlung des erhöhten intraokularen Druckes. Albrecht Von Graefes Arch Klin Exp Ophthalmol 212:129–134

    Article  PubMed  CAS  Google Scholar 

  50. Smith RJ, Nagasubramanian S, Watkins R, Poinoosawmy D (1980) Addition of timolol maleate to routine medical therapy: a clinical trial. Br J Ophthalmol 64:779–781

    Article  PubMed  CAS  Google Scholar 

  51. Ober M, Scharrer A (1979) Timolol und Para-sympathicomimetica bei der Behandlung des erhöhten intraokularen Druckes. Albr Von Graefes Arch Klin Exp Ophthalmol 211:59–66

    Article  CAS  Google Scholar 

  52. Keates EU (1979) Evaluation of timolol maleate combination therapy in chronic open-angle-glaucoma. Am J Ophthalmol 88: 565–571

    PubMed  CAS  Google Scholar 

  53. Merkle W (1981) Timolol in Kombination mit anderen Antiglaucomatosa. Klin Monatsbl Augenheilkd 178:50–54

    Article  PubMed  CAS  Google Scholar 

  54. Sonty S, Schwartz B (1979) The additive effect of timolol on open angle glaucoma patients on maximal medical therapy. Surv Ophthalmol 23:381–388

    Article  PubMed  CAS  Google Scholar 

  55. Nielsen NV, Eriksen JS (1979) Timolol transitory manifestations of dry eyes in long term treatment. Acta Ophthalmol (Copenh) 57: 418–424

    Article  CAS  Google Scholar 

  56. Van Buskirk EM (1979) Corneal anesthesia after timolol maleate therapy. Am J Ophthalmol 88:739–743

    PubMed  Google Scholar 

  57. Calissendorff B (1981) Corneal anaesthesia after topical treatment with timolol maleate. Acta Ophthalmol (Copenh) 59:347–349

    Article  CAS  Google Scholar 

  58. Bischoff P (1978) Erfahrungen mit Timolol in der Glaukomtherapie. Klin Monatsbl Augenheilkd 173:202–207

    PubMed  CAS  Google Scholar 

  59. Shapiro A, Kimchi A, Rod JL, Gotsman MS, Lewis BS (1979) Ocular effects of acebutolol and propranolol. Metab Pedr Ophthalmol 4:87–88

    Google Scholar 

  60. Bonomi L, Zavarise G, Noya E, Michieletto St (1980) Effects of timolol maleate on tear flow in human eyes. Albrecht Von Graefes Arch Klin Exp Ophthalmol 213:19–22

    Article  PubMed  CAS  Google Scholar 

  61. Kitazawa Y, Tsuchisaka H (1980) Effects of timolol on corneal sensitivity and tear production. Int Ophthal Clin 3:25–29

    CAS  Google Scholar 

  62. Aberg G, Adler G, Wikberg J (1979) Inhibition and facilitation of lacrimal flow by ß-adrenergic drugs. Acta Ophthalmol (Copenh) 57:225–235

    Article  CAS  Google Scholar 

  63. Rahi AHS, Chapman CM, Garner A, Wright P (1976) Pathology of practolol induced ocular toxicity. Br J Ophthalmol 60:312–323

    Article  PubMed  CAS  Google Scholar 

  64. Staatz WD, Radius RL, Van Horn DL, Schultz RO (1981) Effects of timolol on bovine corneal endothelial cultures. Arch Ophthalmol 99:660–663

    Article  PubMed  CAS  Google Scholar 

  65. Wind CA (1981) Acute allergic reaction to timolol. Glaucoma 3:56–58

    Google Scholar 

  66. Holtmann HW, Holle JP, Glänzer K (1980) Änderung des bronchialen Strömungswiderstandes bei Asthma bronchiale durch einmalige lokale Applikation von Timolol-0,25%-Augentropfen. Klin Monatsbl Augenheilkd 176:441–444

    Article  PubMed  CAS  Google Scholar 

  67. Van Buskirk EM (1980) Adverse reactions from timolol administration. Ophthalmology (Rochester) 87:447–450

    Google Scholar 

  68. Fraunfelder FT (1980) Interim report: national registry of possible drug-induced ocular side effects. Ophthalmology (Rochester) 87: 87–90

    CAS  Google Scholar 

  69. Britman NA (1979) Cardiac effects of topical timolol. N Engl J Med 300:566

    PubMed  CAS  Google Scholar 

  70. Jones FL (1979) Systemic betablockade by timolol eye drops. N Engl J Med 301:270

    PubMed  Google Scholar 

  71. McMahon ChD, Shaffer RN, Hoskins HD, Hetherington J (1979) Adverse effects experienced by patients taking timolol. Am J Ophthalmol 88:736–738

    PubMed  CAS  Google Scholar 

  72. Yablonski ME, Zimmerman TJ, Waltman SR, Becker B (1978) A fluorophotometric study of the effects of topical timolol on aqueous humor dynamics. Exp Eye Res 27: 135–142

    Article  PubMed  CAS  Google Scholar 

  73. Coakes RL, Brubaker RF (1978) The mechanism of timolol in lowering intraocular pressure. Arch Ophthalmol 96:2045–2048

    Article  PubMed  CAS  Google Scholar 

  74. Missotten L, Goethal M (1977) Timolol reduces the standing potential of the eye. Ophthal Res 9:321–323

    Article  CAS  Google Scholar 

  75. Zimmerman TJ, Harbin R, Pett M, Kaufman HE (1977) Timolol and facility of outflow. Invest Ophthal & Vis Sci 16:623–624

    CAS  Google Scholar 

  76. Neufeld AH, Zawistowski KA, Page ED, Bromberg BB (1978) Influences on the density of β-adrenergic receptors in the cornea and iris-ciliary body of the rabbit. Invest Ophthalmol Vis Sci 17:1069–1075

    PubMed  CAS  Google Scholar 

  77. Neufeld AH (1979) Experimental studies on the mechanism of action of timolol. Surv Ophthalmol 23:363–370

    Article  PubMed  CAS  Google Scholar 

  78. Galant SP, Duriseti L, Underwood S, Insel PA (1978) Decreased beta-adrenergic receptors on polymorphonuclear leukocytes after adrenergic therapy. N Engl J Med 299:933–936

    Article  PubMed  CAS  Google Scholar 

  79. Maguire ME, Ross EM, Gilman AG (1977) β-adrenergic receptor: ligand binding properties and the interaction with adenyl cyclase. Adv Cyclic Nucleotide Res 8:37

    Google Scholar 

  80. Vestal RE, Wood AJJ, Shand DG (1979) Reduced β-adrenoceptor sensitivity in the elderly. Clin Pharmacol Ther 26:181–186

    PubMed  CAS  Google Scholar 

  81. Helal J, Macri FJ, Cavano SJ (1979) Timolol inhibition of aqueous humor production in the cat. Gen Pharmacol 10:377–380

    Article  PubMed  CAS  Google Scholar 

  82. Colasanti BK, Trotter RR (1981) Effects of selective beta1-and beta2-adrenoceptor agonists and antagonists on intraocular pressure in the cat. Invest Ophthalmol Vis Sci 20:69–76

    PubMed  CAS  Google Scholar 

  83. Bartels SP, Roth HO, Jumblatt MM, Neufeld AH (1980) Pharmacological effects of topical timolol in the rabbit eye. Invest Ophthalmol Vis Sci 19:1189–1196

    PubMed  CAS  Google Scholar 

  84. Candia OA, Podos SM, Neufeld AH (1979) Modification by timolol of catecholamine stimulation of chloride transport in isolated corneas. Invest Ophthalmol Vis Sci 18:691–695

    PubMed  CAS  Google Scholar 

  85. Musini A, Fabri B, Bergamschi M, Mandelli V (1971) Comparison of the effect of propranolol, lignocaine, and other drugs on normal and raised intraocular pressure in man. Am J Ophthalmol 72:773–781

    PubMed  CAS  Google Scholar 

  86. Akaike N, Nishi K, Oyama Y (1981) Inhibitory effects of propranolol on the calcium current of Helix neurones. Br J Pharmacol 73:431–434

    PubMed  CAS  Google Scholar 

  87. Nayler WG (1966) The effect of pronethalol and propranolol on lipid-facilitated transport of calcium ions. J Pharmacol Exp Ther 153:479–484

    PubMed  CAS  Google Scholar 

  88. Franciosa JA, Freis ED, Conway J (1973) Antihypertensive and hemodynamic properties of the beta adrenergic blocking agent timolol. Circulation 48:118–124

    PubMed  CAS  Google Scholar 

  89. Wizemann A, Krey H (1981) Thermographische Untersuchungen zum Wirkungsmechanismus von Timolol. Klin Monatsbl Augen-heilkd 178:190–192

    Article  CAS  Google Scholar 

  90. Cristini G, Giovanni A (1979) Pressure lowering effect of timolol with reference to its topical vascular action. Albrecht Von Graefes Arch Klin Exp Ophthalmol 211:325–328

    Article  PubMed  CAS  Google Scholar 

  91. Spaeth GL (1981) Place of timolol in the treatment of glaucoma. Symposium on Glaucoma. Trans New Orleans Acad Ophthalmol Mosby, St. Louis Toronto London

    Google Scholar 

  92. Zimmerman TJ, Kass MA, Yablonski ME, Becker B (1979) Timolol maleate. Efficacy and safety. Arch Ophthalmol 97:656–658

    Article  PubMed  CAS  Google Scholar 

  93. Boger WP, Steinert RF, Puliafito CA, Panvan-Langston DP (1978) Clinical trial comparing timolol ophthalmic solution to pilocarpine in open-angle glaucoma. Am J Ophthalmol 86:8–18

    PubMed  Google Scholar 

  94. Kosman ME (1979) Timolol in the treatment of open angle glaucoma. JAMA 241:2301–2303

    Article  PubMed  CAS  Google Scholar 

  95. Merté HJ, Merkle W (1980) Timolol-Augen-tropfen in der Glaukombehandlung. Ergebnisse einer Langzeitstudie. Klin Monatsbl Augenheilkd 177:562–571

    Article  PubMed  Google Scholar 

  96. Flammer J, Barth D (1980) Kardiovaskuläre Effekte bei lokal appliziertem Timolol. Klin Monatsbl Augenheilkd 176:561–565

    Article  PubMed  CAS  Google Scholar 

  97. Kim JW, Smith PH (1980) Timolol-induced bradycardia. Anesthesia and Analgesia 59:301–303

    PubMed  CAS  Google Scholar 

  98. Batchelor ED, O’Day DM, Shand DG, Wood AJ (1979) Interaction of topical and oral timolol in glaucoma. Am Acad Ophthalmol 86:60–65

    CAS  Google Scholar 

  99. Langham ME (1981) Editorial: β-adrenoceptor blocking drugs and the glaucoma suspect. Ann Ophthalmol 13:273

    PubMed  CAS  Google Scholar 

  100. Haimann MH, Phelps CD (1981) Prophylactic timolol for the prevention of high intraocular pressure after cataract extraction. A randomized, prospective, double-blind trial. Ophthalmology (Rochester) 88:233–238

    CAS  Google Scholar 

  101. Saari KM, Airaksinen PJ, Jaanio EAT (1978) Hypotensive effect of timolol on secondary glaucoma in chronic uveitis. Lancet 25:442

    Article  Google Scholar 

  102. Obstbaum SA, Galin MA (1979) The effects of timolol on cataract extraction and intraocular pressure. Am J Ophthalmol 88: 1017–1019

    PubMed  CAS  Google Scholar 

  103. Packer AJ, Fraioli AJ, Epstein DL (1981) The effect of timolol and acetazolamide on transient intraocular pressure elevation following cataract extraction with alpha-chymotrypsin. Ophthalmologica 88:239–243

    CAS  Google Scholar 

  104. Tilen A, Leuenberger AE (1980) Die Wirkung von Timolol und Acetazolamid auf die intraokulare Druckerhöhung nach Extractio lentis mit Alpha-Chymotrypsin. Klin Monatsbl Augenheilkd 176:558–560

    Article  PubMed  CAS  Google Scholar 

  105. Bischoff P, Speiser P (1980) Timolol — sinnvoll beim hämorrhagischen Glaukom? Klin Monatsbl Augenheilkd 177:235–237

    Article  PubMed  CAS  Google Scholar 

  106. Demmler N, Müller-Bardorff G (1980) Timolol-therapeutische Möglichkeiten in der Praxis bei Engwinkelglaukom (Langzeitbehandlung). Klin Monatsbl Augenheilkd 177: 94–96

    Article  PubMed  CAS  Google Scholar 

  107. Phillips CI (1980) Timolol in operated closed-angle glaucoma. Br J Ophthalmol 64:240–246

    Article  PubMed  CAS  Google Scholar 

  108. Airaksinen PJ, Saari KM, Tiainen J, Jaanio EAT (1979) Management of acute closed-angle glaucoma with miotics and timolol. Br J Ophthalmol 63:822–825

    Article  PubMed  CAS  Google Scholar 

  109. Lass JH, Panvan-Langston D (1979) Timolol therapy in secondary angle-closure glaucoma post penetrating keratoplasty. Ophth AAO 86:51–59

    CAS  Google Scholar 

  110. McMahon CD, Hetherington J, Hoskins HD, Shaffer RN (1981) Timolol and pediatric glaucomas. Ophthalmology (Rochester) 88:249–252

    CAS  Google Scholar 

  111. Boger WP, Walton DS (1981) Timolol in uncontrolled childhood glaucomas. Ophthalmology (Rochester) 88:253–258

    Google Scholar 

  112. Wilson RP, Kanal N, Spaeth GL (1979) Timolol: its effectiveness in different types of glaucoma. Ophth AAO 86:43–50

    CAS  Google Scholar 

  113. Wilson RP, Spaeth GL, Poryzees E (1980) The place of timolol in the practice of ophthalmology. Ophthalmology (Rochester) 87:451–454

    CAS  Google Scholar 

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    G. K. Krieglstein

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    G. K. Krieglstein  & W. Leydhecker  & 

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© 1982 J.F. Bergmann Verlag, München

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Krieglstein, G.K. (1982). Betablocker-Therapie der Glaukome. In: Krieglstein, G.K., Leydhecker, W. (eds) Medikamentöse Glaukomtherapie. Symposion der Deutschen Ophthalmologischen Gesellschaft vom 22. bis 24. April 1982 in Würzburg. J.F. Bergmann-Verlag. https://doi.org/10.1007/978-3-642-80502-8_5

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  • DOI: https://doi.org/10.1007/978-3-642-80502-8_5

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