Experimental Aspects of Implantation of Copper in the Vitreous of the Rabbit Eye

  • A. Ralph Rosenthal
Part of the Symposien der Deutschen Ophthalmologischen Gesellschaft book series (OPH.GES.)

Abstract

The most frequently encountered retained nonmagnetic foreign body clinically and pathologically is composed of pure copper or copper in association with zinc [1, 2]. The difficulties and potential sequelae associated with removal of intravitreal copper fragments in contrast to the possible consequences of retention have led to a series of experiments which deal with implantation of pure and alloyed copper foreign bodies into the vitreous of the rabbit eye. An attempt will be made to use the experimental data to draw practical conclusions which bear on the clinical course and management of patients with retained intravitreal copper foreign bodies.

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References

  1. 1.
    Wilder, H. C.: Intraocular foreign bodies in soldiers. Am. J. Ophthalmol. 31, 57 (1948).PubMedGoogle Scholar
  2. 2.
    Neubauer, H.: Management of nonmagnetic foreign bodies. Int. Ophthalmol. Clin. 8, 237 (1968).PubMedGoogle Scholar
  3. 3.
    Rosenthal, A. R., Appleton, B., Hopkins, J. L.: Intraocular copper foreign bodies. Am. J. Ophthalmol. 78, 671 (1974).PubMedGoogle Scholar
  4. 4.
    Neubauer, H., Bös, R.: Chalcosis corporis vitrei. Ber. dtsch. ophthalmol. Ges. 68, 98 (1967).Google Scholar
  5. 5.
    Pau, H.: Histological findings in the human eye with retained foreign bodies. Ophthalmologica 157, 206 (1969).PubMedCrossRefGoogle Scholar
  6. 6.
    Tulloh, C. G.: Migration of intraocular foreign bodies. Br. J. Ophthalmol. 40, 173 (1956).PubMedCrossRefGoogle Scholar
  7. 7.
    Goldsmith, M. O.: Survey of intraocular foreign body literature with special reference to spontaneous migration and extrusion. J. Int. Coll. Surg. 43, 630 (1965).PubMedGoogle Scholar
  8. 8.
    Rosenthal, A. R., Hopkins, J. L., Appleton, B., Zimmerman, R.: Studies on intraocular copper foreign bodies—Atomic absorption spectrophotometry. Arch. Ophthalmol. (Chicago) 92, 431 (1974).Google Scholar
  9. 9.
    Walsh, A.: Application of atomic absorption spectra to chemical analysis. Spectrochim Acta 7, 108 (1955).CrossRefGoogle Scholar
  10. 10.
    Elwell, W. T., Gidley, J. A. F.: Atomic absorption spectrophotometry, ed. 2. London: Pergamon Press, 1966.Google Scholar
  11. 11.
    Slavin, W.: Atomic absorption spectroscopy. New York: Interscience Publishers, 1968.Google Scholar
  12. 12.
    Rosenthal, A. R., Appleton, B.: Histochemical localization of intraocular copper foreign bodies. Am. J. Ophthalmol. 79, 613 (1975).PubMedGoogle Scholar
  13. 13.
    Lindquist, R. R.: Studies on the pathogenesis of hepatolenticular degeneration. 2. Cytochemical methods for the localization of copper. Arch. Pathol. 87, 370 (1969).PubMedGoogle Scholar
  14. 14.
    Rao, N. A., Tso, M. O. M., Rosenthal, A. R.: Clinicopathologic study of chalcosis in the human eye. Arch. Ophthalmol. (Chicago), in press.Google Scholar
  15. 15.
    Rosenthal, A. R., Appleton, B., Zimmerman, R., Hopkins, J. L.: Intraocular copper foreign bodies—Use of corticosteroids to suppress inflammation. Arch. Ophthalmol. (Chicago), in press.Google Scholar
  16. 16.
    Thorpe, H. E.: Intraocular nonmagnetic foreign bodies. Tr. Amer. Acad. Ophthalmol, and Otolaryngol. 60, 694 (1956).Google Scholar
  17. 17.
    Cairns, J. E., Williams, H. P., Walshe, J. M.: “Sunflower cataract” in Wilson’s Disease. Brit. Med. J. 3, 95 (1969).PubMedCrossRefGoogle Scholar
  18. 18.
    Delbecque, Ph., Sourdille, J., Delthil, S.: Traitement de la chalcose oculaire d’origine traumatique par la penicillamine. Bull. Soc. franc. Ophtalmol. 79, 275 (1966).Google Scholar

Copyright information

© J. F. Bergmann-Verlag, München 1977

Authors and Affiliations

  • A. Ralph Rosenthal
    • 1
  1. 1.Division of OphthalmologyStanford University Medical CenterStanfordUSA

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