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Clinical Applications of Neuroimaging Using Echo-Planar Imaging

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Echo-Planar Imaging

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Abstract

With echo-planar imaging (EPI) images may be acquired in less than 1 s [98], providing many advantages relevant to clinical diagnosis. In addition to the practical virtues of faster image acquisition and reduced sensitivity to motion artifact, the technique allows investigation of physiological processes such as diffusion and perfusion.

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References

  1. Aronen HJ, Gazit IE, Louis DN et al (1994) Cerebral blood volume maps of gliomas: comparison with tumor grade and histologic findings. Radiology 191:41–51

    PubMed  CAS  Google Scholar 

  2. Astrup J, Siesjo BK, Symon L (1981) Thresholds in cerebral ischemia- the ischemic penumbra. Stroke 12:723–725

    PubMed  CAS  Google Scholar 

  3. Baker LL, Kucharczyk J, Sevick RJ, Minotorovitch J, Moseley M (1991) Recent advances of MR imaging/spectroscopy of cerebral ischemia. AJR 156:1133–1143

    PubMed  CAS  Google Scholar 

  4. Bandettini PA, Wong EC, Hinks RS et al (1992) Time course EPI of human brain function during task activation. Magn Reson Med 25:390–397

    PubMed  CAS  Google Scholar 

  5. Belliveau JW, Rosen BR, Kantor HL et al (1990) Functional cerebral imaging by susceptibility-contrast NMR. Magn Reson Med 14:538–546

    PubMed  CAS  Google Scholar 

  6. Benecke R, Meyer B, Freund H-J (1991) Reorganisation of descending motor pathways in patients after hemispherectomy and severe hemispheric lesions demonstrated by magnetic brain stimulation. Exp Brain Res 83:419–426

    PubMed  CAS  Google Scholar 

  7. Bloembergen N (1957) Proton relaxation times in paramagnetic solutions. J Chem Phys 27:527

    Google Scholar 

  8. Brant-Zawadzki M (1991) Pitfalls of contrast-enhanced imaging in the nervous system. Magn Reson Med 22:243–248

    PubMed  CAS  Google Scholar 

  9. Brant-Zawadzki M, Berry I, Osaki L et al (1986) Gd-DTPA in clinical MR of the brain. I. Intraaxial lesions. AJNR 8:781–788

    Google Scholar 

  10. Bruening R, Kwong K, Vevea M et al (1994a) Cerebral blood volume (CBV) maps in primary brain tumors — implementation of T1-effects using echo planar imaging (EPI). In: Proceedings of the Society for Magnetic Resonance, p 196

    Google Scholar 

  11. Bruening R, Campbell T, Niemi P, Rosen BR (1994b) T2-weighted imaging of human brain tumors using 512” Echo planar imaging (EPI) In: Proceedings of the Society for Magnetic Resonance, p 521

    Google Scholar 

  12. Brunberg JA, Chenevert TL, Ross DA et al (1993) In vivo MR determination of water diffusion coefficients and diffusion anisotropy: correlation with structural alteration in astrocytes of the cerebral hemispheres (abstract). In: Book of abstracts. American Society of Neuroradiology, Chicago, p 71

    Google Scholar 

  13. Bryan RN, Levy LM, Whitlow WD et al (1991) Diagnosis of acute cerebral infarction: comparison of CT and MR imaging. AJNR 12:611–620

    PubMed  CAS  Google Scholar 

  14. Busza AL, Allen KL, King MD et al (1992) Diffusion-weighted imaging studies of cerebral ischemia in gerbils. Potential relevance to energy failure. Stroke 23:1602–1612

    PubMed  CAS  Google Scholar 

  15. Chien D, Buxton RB, Kwong KK et al (1990) MR diffusion imaging of the human brain. J Comput Assist Tomogr 14:514–520

    PubMed  CAS  Google Scholar 

  16. Chien D, Kwong KK, Gress DR et al (1992) MR diffusion imaging of cerebral infarction in humans. AJNR 13:1097–1102

    PubMed  CAS  Google Scholar 

  17. Chimowitz MI, Logogian EL, Caplan LR (1990) The accuracy of bedside neurological diagnosis. Ann Neurol 28:78–85

    PubMed  CAS  Google Scholar 

  18. Chollet F, DiPiero V, Wise RJS et al (1991) The functional anatomy of motor cortex recovery after stroke in humans: a study with positron emission tomography. Ann Neurol 29:63–71

    PubMed  CAS  Google Scholar 

  19. Connelly A, Jackson GD, Frackowiak RSJ et al (1993) Functional mapping of activated human primary cortex with a clinical MR imaging system. Radiology 188:125–130

    PubMed  CAS  Google Scholar 

  20. Dardzinski BJ, Sotak CH, Fisher M et al (1993) Apparent diffusion coefficient mapping of experimental focal cerebral ischemia using diffusion-weighted echo-planar imaging. Magn Reson Med 30:318–25

    PubMed  CAS  Google Scholar 

  21. Davis D, Ulatowski J, Eleff S et al (1994) Rapid monitoring of changes in water diffusion coefficients during reversible ischemia in cat and rat brain. Magn Reson Med 31:454–460

    PubMed  CAS  Google Scholar 

  22. de Crespigny AJ, Wendland MF, Derugin N, Koznieska E, Moseley ME (1992) Real-time observation of transient focal ischemia and hyperemia in cat brain. Magn Reson Med 27:391–397

    PubMed  Google Scholar 

  23. de Crespigny AJ, Wendland MF, Derugin N et al (1993a) Rapid MR imaging of a vascular challenge to focal ischemia in cat brain. J Magn Reson Imaging 4:475–481

    Google Scholar 

  24. de Crespigny AJ, Tsuura M, Mosely ME, Kucharczyk J (1993b) Perfusion and diffusion MR imaging of thromboembolic stroke. J Magn Reson Imaging 3:746–54

    PubMed  Google Scholar 

  25. de Crespigny A, Yenari M, Enzmann D et al (1994) Navigated spin-echo diffusion imaging of human stroke. In: Proceedings of the Society for Magnetic Resonance, p 137

    Google Scholar 

  26. Delannoy J, Le Bihan D, Hoult D, Levin R (1990) Hyperthermia system combined with an MRI unit. Med Phys 17:855–860

    PubMed  CAS  Google Scholar 

  27. Douek P, Turner R, Pekar J et al (1991) MR color mapping of myelin fiber orientation. J Comput Assist Tomogr 15:923–929

    PubMed  CAS  Google Scholar 

  28. Edelman RR, Mattle HP, Atkinson DJ et al (1990) Cerebral blood flow: assessment with dynamic contrast-enhanced T2*-weighted MR imaging at 1.5 T. Radiology 176:211–220

    PubMed  CAS  Google Scholar 

  29. Edelman RR, Siewert B, Darby DG, Thangaraj V, Nobre AC, Mesulam MM, Warach S (1994) Qualitative mapping of cerebral blood flow and functional localization with echo-planar MR imaging and signal targeting with alternating radio frequency. Radiology 192:513–520

    PubMed  CAS  Google Scholar 

  30. Faiss JH, Rijntjes M, Weiller CS et al (1994) Motor recovery following cerebral infarction visualized by functional MRI. In: Proceedings of the Society for Magnetic Resonance, p 333

    Google Scholar 

  31. Farmer SF, Harrison LM, Ingram DA, Stephens JA (1991) Plasticity of central motor pathways in children with hemiplegie cerebral palsy. Neurology 41:1505–1510

    PubMed  CAS  Google Scholar 

  32. Feinberg D, Mark A (1987) Human brain motion and cerebrospinal fluid circulation demonstrated with MR velocity imaging. Radiology 163:793–799

    PubMed  CAS  Google Scholar 

  33. Felix R, Schoerner W, Lanaido M et al (1985) Brain tumors: MR imaging with Gadolinium-DTPA. Radiology 156:681–688

    PubMed  CAS  Google Scholar 

  34. Fisel CR, Moore Jr, Garrido L et al (1989) A general model for susceptibility-based MR contrast (abstract). In: Book of abstracts. Society of Magnetic Resonance in Medicine, Berkeley, p 324

    Google Scholar 

  35. Frahm J, Bruhn H, Merbolt KD, Hänicke W (1992) Dynamic MR imaging of human brain oxygenation and photic stimulation. JMRI 2:501–505

    PubMed  CAS  Google Scholar 

  36. Fries W, Danek A, Scheidtmann K, Hamburger C (1993) Motor recovery following capsular stroke. Brain 116:369–382

    PubMed  Google Scholar 

  37. Garcia JH, Anderson ML (1989) Physiopathology of cerebral ischemia. Crit Rev Neurobiol 4:303–324

    PubMed  CAS  Google Scholar 

  38. Gowland P, Mansfield P, Bullock P et al (1992) Dynamic studies of gadolinium uptake in brain tumors using inversion recovery echo-planar imaging. Magn Reson Imaging 26:241–58

    CAS  Google Scholar 

  39. Gyngell ML, Back T, Hoehn-Berlage M et al (1994) Transient cell depolarization after permanent middle cerebral artery occlusion: an observation between diffusion-weighted MRI and localized 1H-MRS. Magn Reson Med 31:337–341

    PubMed  CAS  Google Scholar 

  40. Haimes AB, Zimmerman RD, Morgello S et al (1989) MR imaging of brain abscesses. AJR 152:1073–1085

    PubMed  CAS  Google Scholar 

  41. Hajnal JV, Doran M, Hall AS et al (1991) MR imaging of anisotropically restricted diffusion of water in the nervous system: technical, anatomic, and pathologic considerations. J Comput Assist Tomogr 15:1–18

    PubMed  CAS  Google Scholar 

  42. Hakim AM (1987) The cerebral ischemic penumbra. Can J Neurol Sci 14:557–559

    PubMed  CAS  Google Scholar 

  43. Hasegawa Y, Latour LL, Sotak CH et al (1994) Spreading waves of reduced diffusion coefficient of water in the rat brain. Neurology 44 [Suppl 2]:A341

    Google Scholar 

  44. Henkelman RM (1990) Diffusion-weighted MR imaging: a useful adjunct to clinical diagnosis or a scientific curiosity? AJNR 11:932–934

    Google Scholar 

  45. Jolescz FA, Higuchi N, Bleier AR, Jakab P (1990) MRI of laser effects on tissue. Magn Reson Imaging 8(P):156

    Google Scholar 

  46. Just M, Thelen M (1988) Tissue characterization with T1, T2, and proton density values: results in 160 patients with brain tumors. Radiology 169:779–785

    PubMed  CAS  Google Scholar 

  47. Koenig SH, Brown RD III, Spiller M, Lundbom N (1990) Relaxometry of the brain: why white matter appears bright in MRI. Magn Reson Med 14:482–495

    PubMed  CAS  Google Scholar 

  48. Kucharczyk J, Chew W, Derugin N et al (1989) Nicardipine reduces ischemic brain injury: magnetic resonance imaging/spectroscopy study in cats. Stroke 20:268–274

    PubMed  CAS  Google Scholar 

  49. Kucharczyk J, Mintorovitch J, Mosely ME et al (1991) Ischemic brain damage: reduction by sodium channel ion channel modulator RS-87476. Radiology 179:221–227

    PubMed  CAS  Google Scholar 

  50. Kucharczyk J, Vexier ZS, Roberts TP et al (1993) Echo-planar perfusion-sensitive MR imaging of acute cerebral ischemia. Radiology 188:711–717

    PubMed  CAS  Google Scholar 

  51. Kwong K, Belliveau JW, Chesler DA et al (1992) Dynamic magnetic resonance imaging of human brain activity during primary sensory stimulation. Proc Natl Acad Sci USA 89:5675–5679

    PubMed  CAS  Google Scholar 

  52. Larsson HBW, Christiansen P, Thomsen C et al (1990) In vivo measurement of water self diffusion in patients with chronic multiple sclerosis. Book of abstracts. Society of Magnetic Resonance in Medicine, 9th annual meeting, New York, p 150

    Google Scholar 

  53. Le Bihan D (1991) Molecular diffusion nuclear magnetic resonance imaging. Magn Reson Q 7:1–30

    PubMed  Google Scholar 

  54. Le Bihan D, Breton E, Lallemand D et al (1986) MR imaging of intravoxel incoherent motion: applications to diffusion and perfusion in neurologic disorders. Radiology 161:401–407

    PubMed  Google Scholar 

  55. Le Bihan D, Delannoy J, Levin RL (1989) Temperature mapping with MR imaging of molecular diffusion: application to hyperthermia. Radiology 171:853–857

    PubMed  Google Scholar 

  56. Le Bihan D, Turner R, Moonen CTW, Pekar J (1991) Imaging of diffusion and microcirculation with gradient sensitization: design, strategy and significance. J Magn Reson Imaging 1:7–28

    PubMed  Google Scholar 

  57. Le Bihan D, Douek P, Argyropoulou M et al (1993) Diffusion and perfusion magnetic resonance imaging in brain tumors. Top Magn Reson Imaging 5:25–31

    PubMed  Google Scholar 

  58. Lee C, Dean BL, Kirsch JE et al (1992) Cerebral infarction: assessment of patterns using ultra-fast MR contrast imaging. AJNR 13:277–279

    PubMed  CAS  Google Scholar 

  59. Lundblom N, Katevuo K, Kuomo M et al (1992) T1 in subacute and chronic brain infarctions: time-dependent development. Invest Radiol 27:673–680

    Google Scholar 

  60. Mansfield P, Coxon R, Glover P (1994) Echo-planar imaging of the brain at 3.0 T: first normal volunteer results. J Comput Assist Tomogr 18:339–343

    PubMed  CAS  Google Scholar 

  61. Mark AS, Feinberg DA, Brant-Zawasski MN (1987) Changes in size and magnetic resonance signal intensity of the cerebral CSF spaces during the cardiac cycle, as studied by gated, high resolution MRI. Invest Radiol 22:290–297

    PubMed  CAS  Google Scholar 

  62. Merboldt KD, Hanicke W, Bruhn H, Gynell ML, Frahm J (1992) Diffusion imaging of the human brain in vivo using high speed STEAM MRI. Magn Reson Med 23:179–192

    PubMed  CAS  Google Scholar 

  63. Mikulis D, Chien D, Kwong K et al (1988) Diffusion magnetic resonance imaging in multiple sclerosis. Book of abstracts. Society of Magnetic Resonance in Medicine, 7th annual meeting, New York, p 762

    Google Scholar 

  64. Minematsu K, Fischer M, Li L et al (1992a) A non-competitive NMDA antagonist, CNS-1102, reduces ischemic injury in vivo and postmortem infarction area (abstract). Neurology 42 [Suppl 3]:292

    Google Scholar 

  65. Minematsu K, Li L, Sotak M et al (1992b) Reversible focal ischemic injury demonstrated by diffusion-weighted magnetic resonance imaging in rats. Stroke 23:1304–1311

    PubMed  CAS  Google Scholar 

  66. Minematsu K, Li L, Fischer M et al (1992c) Diffusion-weighted magnetic resonance imaging: rapid and quantitative detection of focal brain ischemia. Neurology 42:235–240

    PubMed  CAS  Google Scholar 

  67. Minematsu K, Fisher M, Li L et al (1993) Effects of a novel NMDA antagonist on experimental stroke rapidly and quantitatively assessed by diffusion-weighted MRI. Neurology 43:397–406

    PubMed  CAS  Google Scholar 

  68. Mintorovitch J, Mosely ME, Chileuitt L et al (1991) Comparison of diffusion- and T2-weighted MRI for the early detection of cerebral ischemia and reperfusion in rats. Magn Reson Med 18:39–50

    PubMed  CAS  Google Scholar 

  69. Moonen CTW, Pekar J, de Vleeschouwer MHM et al (1991) Restricted and anisotropic displacement of water in healthy cat brain and in stroke studied by NMR diffusion imaging. Magn Reson Med 19:317–322

    Google Scholar 

  70. Moseley ME, Cohen Y, Mintorovitch J et al (1990a) Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn Reson Med 14:330–346

    PubMed  CAS  Google Scholar 

  71. Moseley ME, KucharczykJ, Mintorovitch J et al (1990b) Diffusion-weighted MR imaging of acute stroke: correlation with T2-weighted and magnetic susceptibility-enhanced MR imaging in cats. AJNR 11:423–42

    PubMed  CAS  Google Scholar 

  72. Moseley ME, Cohen Y, Kucharzcyk J et al (1990c) Diffusion-weighted MR imaging of anisotropic water diffusion in cat central nervous system. Radiology 176:439–445

    PubMed  CAS  Google Scholar 

  73. Moseley ME, Wendland MF, Kucharzyk J (1991a) Magnetic resonance imaging of diffusion and perfusion. Top Magn Reson Imaging 3:50–67

    PubMed  CAS  Google Scholar 

  74. Moseley M, Kucharczyk J, Asgari HS, Norman D (1991b) Anisotropy in diffusion-weighted MRI. Magn Reson Med 19:321–326

    PubMed  CAS  Google Scholar 

  75. National Institute of Neurological Disorders and Stroke (NINDS) (1990) Special report: classification of cerebrovascular diseases. III. Stroke 21:637–676

    Google Scholar 

  76. Norbash AM, Glover GH, Enzmann DR (1992) Intracerebral lesion contrast with spin-echo and fast spin-echo pulse sequences. Radiology 185:661–665

    PubMed  CAS  Google Scholar 

  77. Norris JW, Hachinski VC (1982) Misdiagnosis of stroke. Lancet 1:328–331

    PubMed  CAS  Google Scholar 

  78. Ogawa S, Lee TM, Kay AR, Tank DW (1990) Brain magnetic resonance imaging with contrast dependent on blood oxygenation. Proc Natl Acad Sci USA 87:9868–9872

    PubMed  CAS  Google Scholar 

  79. Ogawa S, Tank DW Menon R et al (1992) Intrinsic signal changes accompanying sensory stimulation: functional brain mapping with magnetic resonance imaging. Proc Natl Acad Sci USA 89:5951–5955

    PubMed  CAS  Google Scholar 

  80. Ordidge RJ, Guilfoyle DN, Gibbs P, Mansfield P (1989) Real-time flow measurements using echo-planar imaging. Proceedings of the 8th annual meeting of the Society of Magnetic Resonance in Medicine (SMRM), Amsterdam, vol 2, p 889

    Google Scholar 

  81. Ordidge RJ, Helpern JA, Qing ZX, Knight RA, Nagesh V (1994) Correction of motional artifacts in diffusion-weighted MR images using navigator echoes. Magn Reson Imaging 12:455–460

    PubMed  CAS  Google Scholar 

  82. Rimmington JE, Lin J.-R, Santosh C, Best JJK (1994) Functional MRI at 1 tesla: activation of primary motor cortex and supplementary motor area during complex finger tasks in control and hemiplegie subjects. In: Proceedings of the Society for Magnetic Resonance, p 671

    Google Scholar 

  83. Roberts DA, Detre JA, Insko EK et al (1992) Cerebral perfusion imaging in human brain at 1.5T using adiabatic inversion of the arterial input (abstract). 11th annual meeting of the Society of Magnetic Resonance in Medicine, book of abstracts. Society of Magnetic Resonance in Medicine, Berkley, vol 1, p 305

    Google Scholar 

  84. Rosen BR, Belliveau JW, Chien D (1989) Perfusion imaging by nuclear magnetic resonance. Magn Reson Q 5:263–281

    PubMed  CAS  Google Scholar 

  85. Rosen BR, Belliveau JW, Verea JM, Brady TJ (1990) Perfusion imaging with NMR contrast agents. Magn Reson Med 14:249–265

    PubMed  CAS  Google Scholar 

  86. Rosen BR, Belliveau JW, Aronen HJ et al (1991) Susceptibility contrast imaging of cerebral blood volume:, human experience. Magn Reson Med 22:293–299

    PubMed  CAS  Google Scholar 

  87. Rutherford MA, Cowan FM, Manzur AY et al (1991) MR imaging of anisotropically restricted diffusion in the brain of neonates and infants. J Comput Assist Tomogr 15:188–198

    PubMed  CAS  Google Scholar 

  88. Sakuma H, Nomura Y, Takeda K et al (1991) Adult and neonatal human brain: diffusional anisotropy and myelination with diffusion-weighted MR imaging. Radiology 180:229–233

    PubMed  CAS  Google Scholar 

  89. Schmitt F, Stehling MK, Ladebeck R, Fang M, Quaiyumi A, Barschneider E, Huk WJ (1992) Echo-Planar imaging of the central nervous system at 1.0 T. J Magn Reson Imaging 2:473–478

    PubMed  CAS  Google Scholar 

  90. Schwaighofer BW, Klein MV, Wesbey G et al (1990) Clinical experience with routine Gd-DTPA administration for MR imaging of the brain. J Comput Assist Tomogr 14:11–17

    PubMed  CAS  Google Scholar 

  91. Sevick RJ, Kanda F, Mintorovich J et al (1992) Cytotoxic brain edema: assessment with diffusion-weighted MR imaging. Radiology 185:687–690

    PubMed  CAS  Google Scholar 

  92. Sibson NR, Gill R, Maskell L et al (1994) The neuroprotective effect of MK-801 in a permanent model of focal cerebral ischemia in the rat assessed using diffusion weighted magnetic resonance imaging. In: Proceedings of the Society for Magnetic Resonance, p 1376

    Google Scholar 

  93. Siewert B et al (1995) Stroke and ischemia. MRI Clin North Am 3:529–540

    CAS  Google Scholar 

  94. Siewert B, Patel MR, Mueller MF, Gaa J, Darby DG, Poser CM, Wieloposki PA, Edelman RR, Warach S (1995) Detection of brain lesions using echo-planar imaging: multiple sclerosis. Radiology 162:765–771

    Google Scholar 

  95. Simonson TM, Crosby DL, Fisher DJ et al (1994) Echo-planar FLAIR in the evaluation of intracranial lesions. In: Proceedings of the Society for Magnetic Resonance, p 522

    Google Scholar 

  96. Solomon I (1955) Relaxation processes in a system of two spins. Phys Rev 99:559

    CAS  Google Scholar 

  97. Steen RG (1992) Edema and tumor perfusion: characterization by quantitative 1H MR imaging. AJR 158:259–264

    PubMed  CAS  Google Scholar 

  98. Stehling MK, Turner R, Mansfield P (1991a) Echo-planar imaging: magnetic resonance imaging in a fraction of a second. Science 254:43–50

    PubMed  CAS  Google Scholar 

  99. Stehling MK, Firth JL, Worthington BS et al (1991b) Observation of cerebrospinal fluid flow with echo-planar magnetic resonance imaging. BR J Radiol 64:89–97

    PubMed  CAS  Google Scholar 

  100. Stehling MK, Schmitt F, Ladebeck R (1993) Echo-planar MR imaging of human brain oxygenation changes. J Magn Reson Imaging 4:471–474

    Google Scholar 

  101. Stejskal EO, Tanner JE (1965) Spin diffusion measurements: spin echoes in the presence of a time-dependent field gradient. J Chem Phys 42:288–292

    CAS  Google Scholar 

  102. Thulborn KR, Waterton JC, Matthews PM, Radda GK (1982) Oxygenation dependence of the transverse relaxation time of water protons in whole blood at high field. Biochem Biophys Acta 714:265–270

    PubMed  CAS  Google Scholar 

  103. Tien RD, Felsberg GJ, Friedman H et al (1994) MR imaging of high grade cerebral gliomas: value of diffusion-weighted echoplanar pulse sequences. AJR 162:671–677

    PubMed  CAS  Google Scholar 

  104. Tsuruda JS, Chew WM, Mosely ME, Norman D (1990) Diffusion-weighted MR imaging of the brain: value of differentiating between extraaxial cysts and epidermoid tumors. AJNR 11:925–931

    PubMed  CAS  Google Scholar 

  105. Turner R, Le Bihan D, Maier J et al (1990) Echo-planar imaging of intravoxel incoherent motion. Radiology 177:407–414

    PubMed  CAS  Google Scholar 

  106. Turner R, LeBihan D, Chesnick AS (1991a) Echo-planar imaging of diffusion and perfusion. Magn Reson Med 19:247–253

    PubMed  CAS  Google Scholar 

  107. Turner R, Le Bihan D, Moonen CTW et al (1991b) Echo planar time course MRI of cat brain oxygenation changes. Magn Reson Med 22:159–166

    PubMed  CAS  Google Scholar 

  108. Turner R, Jezzard P, Wen H et al (1993) Functional mapping of the human visual cortex at 4 and 1.5 tesla using deoxygenation contrast EPI. Magn Reson Med 29:227–229

    Google Scholar 

  109. Villringer A, Rosen RB, Belliveau JW et al (1988) Dynamic imaging with lanthanide chelates in normal brain: contrast due to magnetic susceptibility effects. Magn Reson Med 6:164–174

    PubMed  CAS  Google Scholar 

  110. von Arbin M, Britton M, de Faire U et al (1981) Accuracy of bedside diagnosis in stroke. Stroke 12:288–293

    Google Scholar 

  111. Warach S, Chien D, Li W et al (1992a) Fast magnetic resonance diffusion-weighted imaging of acute human stroke. Neurology 42:1717–1723

    PubMed  CAS  Google Scholar 

  112. Warach S, Li W, Ronthal M, Edelman RR (1992b) Acute cerebral ischemia: evaluation with dynamic contrast-enhanced MR and MR angiography. Radiology 182:41–47

    PubMed  CAS  Google Scholar 

  113. Warach S, Wielopolski P, Edelman RR (1993) Identification of the ischemic penumbra of acute human stroke using echo planar diffusion and perfusion imaging. Proceedings of the 12th annual scientific meeting of the Society of Magnetic Resonance in Medicine, p 263

    Google Scholar 

  114. Warach S, Gaa J, Siewert B, Wielpolski PA, Edelman RR (1995) Acute human stroke studied by whole brain echo planar diffusion weighted MRI. Ann Neurol 161:233–236

    Google Scholar 

  115. Watanabe M, Tanaka R, Takeda N (1992) Magnetic resonance imaging and histopathology of cerebral gliomas. Neuroradiology 34:463–469

    PubMed  CAS  Google Scholar 

  116. Weder B, Knorr U, Herzog H et al (1994) Tactile exploration of shape after subcortical ischemic infarction studied with PET. Brain 117:593–605

    PubMed  Google Scholar 

  117. Weiller CS, Chollet F, Friston KJ et al (1992) Functional reorganization of the brain in recovery from striatocapsular infarction in man. Ann Neurol 31:463–472

    PubMed  CAS  Google Scholar 

  118. Weiller C, Ramsay SC, Wise RJS, Friston KJ, Frackowiak RSJ (1993) Individual patterns of functional reorganization in the human cerebral cortex after capsular infarction. Ann Neurol 33:181–189

    PubMed  CAS  Google Scholar 

  119. Weisskopf R, Belliveau J, Kwong K, Rosen B (1992) Functional MR imaging of capillary hemodynamics. In: Potchen E (ed) Magnetic resonance angiography: concepts and applications. St Louis, Mosby, pp 473–484

    Google Scholar 

  120. Weisskopf RM, Boxerman JL, Sorensen AG et al (1994) Simultaneous blood volume and permeability mapping using a single Gd-based contrast injection. In: Proceedings of the Society for Magnetic Resonance, p 279

    Google Scholar 

  121. Wendland MF, White DL, Aicher KP et al (1991) Detection of echo-planar MR imaging of transit susceptibility contrast medium in a rat model of regional brain ischemia. J Magn Reson Imaging 1:285–292

    PubMed  CAS  Google Scholar 

  122. Williams DS, Detre JA, Leigh JS, Koretsky AP (1992) Magnetic resonance imaging of perfusion using spin echo inversion of arterial water. Proc Natl Acad Sci USA 82:212–216

    Google Scholar 

  123. Worthington BS, Bullock P, Stehling M et al (1991) Clinical experience with contrast enhanced echo-planar imaging of the brain. Magn Reson Med 22:255–258

    PubMed  CAS  Google Scholar 

  124. Yuh WTC, Crain MR, Loes DJ et al (1991) MR imaging of cerebral ischemia: findings in the first 24 hours. AJNR 12:621–629

    PubMed  CAS  Google Scholar 

  125. Zhong J, Petroff OA, Prichard JW, Gore JC (1993) Changes in water diffusion and relaxation properties of rat cerebrum during status epilepticus. Magn Reson Med 30:241–246

    PubMed  CAS  Google Scholar 

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Siewert, B., Warach, S. (1998). Clinical Applications of Neuroimaging Using Echo-Planar Imaging. In: Echo-Planar Imaging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80443-4_14

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