Skip to main content
SpringerLink
Log in

Wertigkeit von Laborparametern für Diagnostik und Therapiekontrolle kardialer Erkrankungen

  • Chapter
Herzerkrankungen und Interventions-möglichkeiten

  • 98 Accesses

Zusammenfassung

Um die oftmals beschränkten Ressourcen der kardialen Diagnostik optimal zu nützen, müssen die Strategien der Zuweisung zu invasiven (Koronarangiographie) und nichtinvasiven kardiologischen Untersuchungen (Echokardiographie und Szintigraphie) verbessert werden. Bei den notwendigen Voruntersuchungen der Patienten können sensitive und spezifische Labortests zur Diagnose von akuten und chronischen Herzerkrankungen eine wichtige Rolle erlangen.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 64.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  1. Adams JE III, Bodor GS, Davila-Roman VG et al. (1993) Cardiac troponin I - a marker with high specifity for cardiac injury. Circulation 88: 101–106

    PubMed  Google Scholar 

  2. Andersen PAW, Malouf NN, Oakeley AE, Pagani ED, Allen PD (1991) Troponin T isoform expression in humans: a comparison among normal and failing adult heart; fetal heart and adult and skeletal muscle. Circ Res 69: 1226–1233

    Google Scholar 

  3. Bhayana V, Cohoe S, Leung FY, Jablonsky G, Henderson AR (1993) Diagnostic evaluation of creatine kinase-2-mass and creatine kinase-3 and 2-isoform ratios in early diagnosis of acute myocardial infarction. Clin Chem 39: 488–495

    PubMed  CAS  Google Scholar 

  4. Burlina A, Zaniotto M, Secchiero S, Rubin D, Accorsi F (1994) Troponin T as a marker of ischemic myocardial injury. Clin Biochem 27: 113–121

    Article  PubMed  CAS  Google Scholar 

  5. Choy AMJ, Darbar D, Lang CC et al. (1994) Detection of left ventricular dysfunction after acute myocardial infarction: comparison of clinical, echocardiographic, and neurohormonal methods. Br Heart J 72: 16–22

    Article  PubMed  CAS  Google Scholar 

  6. Davidson NC, Coutie WJ, Struthers AD (1995) N-terminal proatrial natriuretic peptide and brain natriuretic peptid are stable for up to 6 hours in whole blood in vitro. Circulation 91: 1276–1277

    PubMed  CAS  Google Scholar 

  7. Drexel H, Dworzak E, Kirchmair M et al. (1983) Myoglobinemia in the very early phase of acute myocardial infarction. Am Heart J 105: 642–651

    Article  PubMed  CAS  Google Scholar 

  8. Farah CS, Reinach FC (1995) The troponin complex and regulation of muscle concentration. FASEB J 9: 755–767

    PubMed  CAS  Google Scholar 

  9. Friedl W, Mair J, Thomas S, Pichler M, Puschendorf B (1996) Natriuretic peptides and cyclic guanosine monophosphate in asysmptomatic left ventricular dysfunction. Heart 76: 129–136

    Article  PubMed  CAS  Google Scholar 

  10. Gibler WB, Young GP, Hedges JR et al. (1992) Acute myocardial infarction in chest pain patients with nonodiagnostic EGGs: Serial CK-MB sampling in the emergency department. Ann Emerg Med 21: 504–512

    Google Scholar 

  11. Hall C, Rouleau JL, Moye E et al. (1994) N-terminal proatrial natriuretic factor - an independent predictor of long term prognosis after myocardial infarction. Circulation 89: 1934–1942

    PubMed  CAS  Google Scholar 

  12. Hall C, Aaberge L, Stokke O (1995) In vitro stability of N-terminal proatrial natriuretic factor in unfrozen samples: an important perequisite for ist use as a biochemical parameter of atrial pressure in clinical routine. Circulation 91: 911

    PubMed  CAS  Google Scholar 

  13. Hamm CW, Ravkilde J, Gerhart W et al. (1992) The prognositc value of serum troponin T in unstable angina. N Engl J Med 327: 146–150

    Article  PubMed  CAS  Google Scholar 

  14. Hunt PJ, Yandle TG, Nicholls MG et al. (1995) The aminoterminal portion of pro-brain natriuretic peptide ( Pro-BNP) circulates in human plasma. Biochem Biophys Res Commun 214: 1175–1183

    Google Scholar 

  15. Ingwal JS, Kramer MF, Fifer M et al. (1985) The creatine kinase system in normal and diseased human myocardial. N. Engl J Med 313: 1050–1054

    Article  Google Scholar 

  16. Jakob G, Mair J, Puschendorf B, Pichler M (1995) Ergometric exercise testing improves the sensitivity of cyclic guanosine 3′5′ monophosphate to diagnose asymptomatic left ventricular dysfunction. Br Heart J 73: 145–150

    Article  PubMed  CAS  Google Scholar 

  17. Johnstone DE, Abdulla A, Arnold JMO et al. (1994) Canadian cardiovascular societies consensus conference. Diagnosis and management of heart failure. Can J Cardiol 10: 613–631

    Google Scholar 

  18. Karrenbrock B, Heim JM, Gerzer R (1990) Effect of molsidomine on ex vivo platelet aggregation and plasma guanosine 3′5′ cyclic monophosphate levels in healthy volunteers. Klin Wochenschr 68: 213–217

    Article  PubMed  CAS  Google Scholar 

  19. Katus HA, Remppis A, Neumann FJ et al. (1991) Diagnostic efficiency of Troponin T measurements in acute myocardial infarction. Circulation 83: 902–912

    PubMed  CAS  Google Scholar 

  20. Katus HA, Muller-Bardorff M, Hallermayer K. (1995)The second generation of the cardiac troponin T ELISA: improved specificity. Clin Chem 41: 1201–1202

    Google Scholar 

  21. Laperche T, Steg PG, Dehoux M et al. (1995) A study of biochemical markers of reperfusion early after thrombolysis for acute myocardial infarction. Circulation 92: 2079–2086

    PubMed  CAS  Google Scholar 

  22. Lauer B, Niederau C, Kühl V, Schannwell M, Schultheiss HP (1995) Assesment of myocardial cell damage in patients with myocarditis by serum levels of cardiac troponin T. Eur Heart J 16 [Suppl 299]: 1710

    Google Scholar 

  23. Lee T, Rouan GW, Weisberg MC et al. (1987) Clinical characteristics and natural history of patients with acute myocardial infarction sent home from the emergency room. Am J Cardiol 60: 219 - 224

    Article  PubMed  CAS  Google Scholar 

  24. Lerman A, Gibbons RJ, Rodeheffer RJ et al. (1993) Circulating N-terminal atrial natriuretic peptide as a marker for symptomless left-ventricular dysfunction. Lancet 341: 1105–1109

    Article  PubMed  CAS  Google Scholar 

  25. Mair J, Artner-Dworzak E, Dienstl A et al. (1991) Early detection of acute myocardial infarction by measurement of mass concentration of creatine kinase-MB. Am J Cardiol 68: 1545–1550

    Article  PubMed  CAS  Google Scholar 

  26. Mair J, Artner-Dworzak E, Lechleitner et al. (1991) Cardiac Troponin T in diagnosis of acute myocardial infarction. Clin Chem 37: 845–852

    PubMed  CAS  Google Scholar 

  27. Mair J, Artner-Dworzak E, Lechleitner P et al. (1992) Early diagnosis of acute myocardial infarction by a newly developed rapid immunoturbidimetric assay for myoglobin. Br Heart J 68: 462–468

    Article  PubMed  CAS  Google Scholar 

  28. Mair J, Puschendorf B, Smidt J et al. (1994) Early release of glycogen phosphorylase in patients with unstable angina and transient ST-T alternations. Br Heart J 72: 125–127

    Article  PubMed  CAS  Google Scholar 

  29. Mair J, Morandell D, Genser N, Lechleitner P, Dienstl F, Puschendorf B (1995) Equivalent early sensitivities of myoglobin, creatine kinase MB mass, creatine kinase isoform ratios, cardiac troponin I and T for acute myocardial infarction. Clin Chem 41: 1266–1272

    PubMed  CAS  Google Scholar 

  30. Mair J, Genser N, Morandell D et al. (1996) Cardiac troponin I in the diagnosis of myocardial injury and infarction. Clin Chim Acta 245: 19–28

    Article  PubMed  CAS  Google Scholar 

  31. Mair P, Mair J, Seibt I, Balogh D, Puschendorf B (1993) Early and rapid diagnosis of perioperative myocardial infarction in aortocoronary bypass surgery by immunoturbidimetric myoglobin measurements. Chest 103: 1508–1511

    Article  PubMed  CAS  Google Scholar 

  32. Mair P, Mair J, Krause EG, Balogh D, Puschendorf B, Rabitzsch G (1994) Glycogen phosphorylase isoenzyme BB mass release after coronary artery bypass grafting. Eur J Clin Chem Clin Biochem 32: 543–547

    PubMed  CAS  Google Scholar 

  33. Michael LH, Hunt JR, Weilbach D (1985) Creatine kinase and phosphorylase in cardiac lymph. Coronary occlusion and reperfusion. Am J Physiol 248: 350–359

    Google Scholar 

  34. Neumeier D, Jockers-Wretou E (1981) Tissue specific and subcellular distribution of creatine kinase isoenzymes. In: Lang H (ed) Creatine kinase isoenzymes - pathophysiology and clinical application. Springer, Berlin Heidelberg New York, pp 85–129

    Chapter  Google Scholar 

  35. Nieuwenhoven FA van, Kleine AH, Wodzig WH et al. (1995) Discrimination between myocardial and skeletal muscle injury by assessment of the plasma ration of myoglobin over fatty acid binding protein. Circulation 92: 2848–2854

    PubMed  Google Scholar 

  36. Ohmann EM, Casey C, Bengston JR, Pryor D, Tomey W, Horgan J (1990) Early detection of acute myocardial infarction; additional information from serum concentrations of myoglobin in patients without ST-elevation. Br Heart J 63: 335–338

    Article  Google Scholar 

  37. Packer M (1992) Pathophysiology of chronic heart failure. Lancet 340: 88–92

    Article  PubMed  CAS  Google Scholar 

  38. Puleo PR, Meyer D, Wathen C et al. (1994) Use of a rapid assay of subforms of creatine kinase MB to diagnose or rule out acute myocardial infarction. N Engl J Med 331: 561–566

    Article  PubMed  CAS  Google Scholar 

  39. Ravkilde J, Nissen H, Horder M, Thygesen K (1995) Independent prognostic value of serum creatine kinase isoenzyme, MB mass, cardiac troponin T and myosin light chain levels in suspected myocardial infarction. J Am Coll Cardiol 25: 574–581

    Google Scholar 

  40. Somer H, Duboeitz V, Donner M (1976) Creatine kinase isoenzymes in neuromuscular diseases. J Neurol Sci 29: 129–136

    Article  PubMed  CAS  Google Scholar 

  41. Sylven C, Jannson E, Book K (1984) Myoglobin content in human skeletal muscle and myocardium: relation to fibre and size and oxidative capacity. Cardiovasc Res 18: 443–446

    Article  PubMed  CAS  Google Scholar 

  42. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A (1994) Myocardial infarction and coronary deaths in the World Health Organization MONICA Project-Registration procedures, event rates, and case-fatality rates 38 populations from 21 countries in four continents. Circulation 90: 583–612

    PubMed  CAS  Google Scholar 

  43. Vorderwinkler KP, Artner-Dworzak E, Jakob G et al. (1991) Release of cyclic guanosine mo-nophosphate evaluated as a diagnostic tool in cardiac diseases. Clin Chem 37: 186–190

    PubMed  CAS  Google Scholar 

  44. Wei CM, Heublein DM, Perrella MA et al. (1993) Natriuretic peptide system in human heart failure. Circulation 88: 1004–1009

    PubMed  CAS  Google Scholar 

  45. Williams JF, Bristow MR, Fowler MB et al. (1995) ACC/AHA Task Force Report.Guidelines for the evaluation and management of heart failure. Circulation 92: 2764–2784

    Google Scholar 

  46. Yoshimura M, Yaue H, Okumura K et al. (1993) Different secretion patterns of atrial natriuretic peptide and brain natriuretic peptide in patients with congestive heart failure. Circulation 87: 464–469

    PubMed  CAS  Google Scholar 

  47. Zabel M, Hohnloser SH, Koster W, Prinz M, Kasper W, Just H (1993) Analysis of creatine kinase, CK-MB, Myoglobin, and troponin T time, activity curves for early assessment of coronary artery reperfusion after intravenous thrombolysis. Circulation 87: 1542–1550

    Google Scholar 

Download references

Authors
  1. B. Puschendorf
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Müllner Hauptstraße 48, A-5020, Salzburg, Österreich

    Felix Unger FESC, FACC (Vorstand der Herzchirurgie Salzburg, Direktor) (Vorstand der Herzchirurgie Salzburg, Direktor)

  2. European Heart Institute, Europäischen Akademie der Wissenschaften und Künste, Waagplatz 3, A-5020, Salzburg, Österreich

    Felix Unger FESC, FACC (Vorstand der Herzchirurgie Salzburg, Direktor) (Vorstand der Herzchirurgie Salzburg, Direktor)

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Puschendorf, B. (1998). Wertigkeit von Laborparametern für Diagnostik und Therapiekontrolle kardialer Erkrankungen. In: Unger, F. (eds) Herzerkrankungen und Interventions-möglichkeiten. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80404-5_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-80404-5_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80405-2

  • Online ISBN: 978-3-642-80404-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation