Application of Ligand-Dependent Site-Specific Recombination in ES Cells
They can be modified in culture and reintroduced back into blastocysts, giving rise to manipulated chimeric animals (Thompson et al. 1989)
They can spontaneously differentiate to various cell types under certain growth conditions.
KeywordsEmbryonic Stem Cell Selectable Marker Gene loxP Site Inducible Expression System Human Progesterone Receptor
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