Supply and Husbandry of Mice for Transgenic Science

  • Jane Morrell
Part of the Springer Lab Manual book series (SLM)


The use of healthy mice kept under good husbandry conditions is of paramount importance for reliable results in transgenic studies. The health status of mice and their husbandry conditions can have a significant impact on experimental results, and therefore must be considered initially when designing the experiment.


Transgenic Line Embryo Transfer Animal House Uterine Horn Laminar Flow Hood 
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  1. Clough G (1982) Environmental effects on animals used in biomedical research. Biol Rev 57: 487–523PubMedCrossRefGoogle Scholar
  2. FELASA Working Group (1994) Recommendations for the health monitoring of mouse, rat, hamster, guinea pig and rabbit breeding colonies. Lab Anim 28: 1–12CrossRefGoogle Scholar
  3. Flecknell PA (1987) Laboratory anaesthesia. An introduction for research workers and technicians. Academic Press, LondonGoogle Scholar
  4. Harkness JE, Wagner JE (1983) The biology and medicine of rabbits and rodents. 3rd edn. Lea & Febiger, LondonGoogle Scholar
  5. Hogan B, Constantini F, Lacy E (1986) In: Manipulating the mouse embryo: a laboratory manual. Cold Spring HarborGoogle Scholar
  6. Kraft LM (1982) Viral diseases of the digestive system, chap 9. In: Foster HL, Small JD, Fox JG (eds) The mouse in biomedical research, vol II. Academic Press, London, pp 173–183Google Scholar
  7. Morrell JM, Gore MA, Nayudu PL (1995) Retrospective observation of the effect of accidental exposure to organophosphates on the success of embryo transfer in mice. Lab Anim Scie 45: 437–440Google Scholar
  8. UFAW (1989a) UFAW guidelines on the care of laboratory animals and their use forGoogle Scholar
  9. scientific purposes. II Pain, analgesia and anaesthesia. UFAW, Potters BarGoogle Scholar
  10. UFAW (1989b) UFAW guidelines on the care of laboratory animals and their use forGoogle Scholar
  11. scientific purposes. III Surgical procedures. UFAW, Potters BarGoogle Scholar
  12. Home Office, 1986 Animals (Scientific Procedures) Act 1986, HMSO, United Kingdom.Google Scholar
  13. Canadian Council on Animal Care (1984) Guide to the care and use of experimental animals: 2. Ottawa: Canadian Council on Animal Care.Google Scholar
  14. Home Office (1989) Code of practice for the housing and care of animals used in scientific procedures. HMSO, UK.Google Scholar
  15. Council of Europe (1986) European convention for the protection of vertebrate animals used for experimental and other scientific purposes. Strasbourg: Council of Europe.Google Scholar
  16. US Animal Welfare Act (1970) 9 CER Part 3.Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1998

Authors and Affiliations

  • Jane Morrell
    • 1
  1. 1.European Molecular Biology LaboratoryHeidelbergGermany

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