Urinary System pp 260-270 | Cite as

Acute Tubular Lesions, Kidney, Rat

  • Roger A. Owen
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


Mild or focal changes are undetectable grossly. Large, pale kidneys that are heavier than normal and that bulge under the capsule are characteristic of widespread tubular damage. On cut surface, a white band in the outer stripe of the outer medulla is characteristic of those compounds that affect the pars recta (Fig. 222), whereas cortical pallor occurs if the pars convoluta is the damaged segment. Papillary or medullary congestion may also be seen.


Synonyms Acute tubular necrosis (ATN) nephrotoxic ATN acute tubular nephrosis acute toxic tubular nephrosis acute toxic tubular nephritis acute tubular degeneration 


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© Springer-Verlag Berlin Heidelberg 1986

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  • Roger A. Owen

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