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Acute Tubular Lesions, Kidney, Rat

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Urinary System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY))

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Abstract

Mild or focal changes are undetectable grossly. Large, pale kidneys that are heavier than normal and that bulge under the capsule are characteristic of widespread tubular damage. On cut surface, a white band in the outer stripe of the outer medulla is characteristic of those compounds that affect the pars recta (Fig. 222), whereas cortical pallor occurs if the pars convoluta is the damaged segment. Papillary or medullary congestion may also be seen.

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Authors
  1. Roger A. Owen
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Editors and Affiliations

  1. Harvard Medical School, ILSI Research Foundation, 1126 Sixteenth Street,N.W., Washington, DC, 20036, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology Emeritus) (Professor of Comparative Pathology Emeritus)

  2. American Health Foundation, One Dana Drive, Valhalla, NY, USA

    Gordon C. Hard BVSc., Ph.D., DSc., FRCPath., FRCVS, FAToxSci. (Director of Administration and Senior Toxicologist) (Director of Administration and Senior Toxicologist)

  3. Medizinische Hochschule Hannover, Institut für Experimentelle Pathologie, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

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© 1986 Springer-Verlag Berlin Heidelberg

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Owen, R.A. (1986). Acute Tubular Lesions, Kidney, Rat. In: Jones, T.C., Hard, G.C., Mohr, U. (eds) Urinary System. Monographs on Pathology of Laboratory Animals. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80335-2_23

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  • DOI: https://doi.org/10.1007/978-3-642-80335-2_23

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  • Print ISBN: 978-3-642-80337-6

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