Urinary System pp 255-260 | Cite as

Chloroform Nephrosis, Male Mouse

  • William W. Carlton
  • Jeffery A. Engelhardt
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)


The kidneys of male mice of susceptible strains exposed to toxic concentrations of chloroform (HCCl3) are acutely swollen and pale with a granular appearance. Often, in survivors, the kidneys have white capsular mottling and cortical streaks due to calcification of necrotic tubules (Deringer et al. 1953). Kidneys are somewhat enlarged, as confirmed by increased renal weight in chloroform-treated male mice (Ahmadizadeh et al. 1984).


Synonyms None 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1986

Authors and Affiliations

  • William W. Carlton
  • Jeffery A. Engelhardt

There are no affiliations available

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