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Urinary System pp 233-238 | Cite as

Infarction, Kidney, Rat, Mouse

  • Charles A. MontgomeryJr.
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)

Abstract

The gross appearance of renal infarcts is dependent upon their age (Sheehan and Davis 1958).During the first few hours after infarction the lesion is red and the overlying capsule is tense. Thecut surfaces of infarcts are characteristically triangular in shape, with the apex pointing toward the medulla. As the lesion ages, the color changes to gray centrally, and there may be a red rim at the margin. In approximately a week, the lesion becomes depressed below the capsular surface and progressively smaller and firmer. Old infarcts eventually lose their triangular shape and become linear. The size of the infarct is dependent upon the size of the obstructed vessel and the age of the lesion. In cases where there is a recurring embolic shower in the kidney, multiple acute and chronic infarcts may be present in the same animal.

Keywords

Ischemic infarct acute or chronic infarct healed infarct 

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© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • Charles A. MontgomeryJr.

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