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Urinary System pp 228-233 | Cite as

Chronic Progressive Nephropathy, Rat

  • Stephen W. Barthold
Part of the Monographs on Pathology of Laboratory Animals book series (LABORATORY)

Abstract

Kidneys of rats with moderate to severe chronic progressive nephropathy (CPN) are enlarged and pale with pitted or granular surfaces (Fig. 194). Small cysts can be visible in the cortex. In advanced disease, kidneys can be enlarged two to three times their normal size. There may also be irregular brown to golden pigmentation radiating from the corticomedullary junction to the surface.

Keywords

Chronic progressive nephrosis chronic nephritis spontaneous nephrosis chronic nephrosis protein overload nephropathy progressive glomerulonephrosis glomerulonephrosclerosis nephritis glomerulonephritis dietarynephritis chronic progressive glomerolunephropathy old rat nephropathy 

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© Springer-Verlag Berlin Heidelberg 1998

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  • Stephen W. Barthold

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