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The Mechanism of Emesis Induced by Chemotherapy and Radiotherapy

  • Paul L. R. Andrews
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)

Abstract

Nausea and vomiting are two of the side-effects of major concern to patients undergoing palliative or curative chemo- or radiotherapy for cancer and both have a variety of deleterious effects on the patient’s quality of life during treatment. Vomiting itself places a considerable physical stress on the body in patients who may already be weakened by their disease and any concomitant surgery. Tearing of the oesophagus (Mallory-Weiss Syndrome) and herniation of the stomach may occur, as can abdominal muscle strain, purpura, fatigue and even fracture of ribs if the vomiting is particularly violent [1]. The main danger is from aspiration of vomitus, although this is considered to be a greater risk in patients vomiting during emergence from anaesthesia.

Keywords

Motion Sickness Nucleus Tractus Solitarius Area Postrema Anticipatory Nausea Delayed Emesis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • Paul L. R. Andrews
    • 1
  1. 1.Department of PhysiologySt George’s Hospital Medical SchoolLondonUK

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