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Alternative Therapies in the Treatment of Chemotherapy-Induced Nausea and Vomiting

  • Jørn Herrstedt
Conference paper
Part of the ESO Monographs book series (ESO MONOGRAPHS)

Abstract

Although it is generally recognised that unorthodox therapies have no objective antitumor activity [1], it is estimated that 30–50% of cancer patients use these unproven methods either alone or along with established cancer therapies [2,3]. Physicians therefore have to be acquainted with alternative therapies, which will only disappear when the majority of malignancies are cured. A large proportion of patients using alternative therapies do so in an attempt to improve resistance and quality of life by mitigating the side-effects of chemotherapy or radiotherapy [3].

Keywords

Motion Sickness Emetogenic Chemotherapy Antiemetic Therapy Antiemetic Effect Anticipatory Nausea 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Jallut OB: What can be done against unproven methods in cancer therapy. The Swiss experience. J Cancer Res Clin Oncol 1990 (116, Suppl, Part II):S950Google Scholar
  2. 2.
    Kjaer M: Unproven methods in cancer therapy in Denmark and Scandinavia. J Cancer Res Clin Oncol 1990 (116, Suppl, Part II):S949Google Scholar
  3. 3.
    Jungi WF: Alternative medicine (AM) in the German-speaking countries in Europe. J Cancer Res Clin Oncol 1990 (116, Suppl, Part ll):S949Google Scholar
  4. 4.
    Coates A, Abraham S, Kaye SB, Sowerbutts T, Frewin C, Fox RM, Tattersall MHN: On the receiving end — patient perception of the side-effects of cancer chemotherapy. Eur J Cancer Clin Oncol 1983 (19):203–208PubMedCrossRefGoogle Scholar
  5. 5.
    Richardson JL, Marks G, Levine A: The influence of symptoms of disease and side effects of treatment on compliance with cancer therapy. J Clin Oncol 1988(6):1746–1752PubMedGoogle Scholar
  6. 6.
    Roila F, Tonato M, Cognetti F et al: Prevention of cisplatin-induced emesis: a double-blind multicenter randomized crossover study comparing ondansetron and ondansetron plus dexamethasone. J Clin Oncol 1991 (9):675–678PubMedGoogle Scholar
  7. 7.
    Smyth JF, Coleman RE, Nicolson M et al: Does dexamethasone enhance control of acute cisplatin induced emesis by ondansetron? Br Med J 1991 (303): 1423–1426CrossRefGoogle Scholar
  8. 8.
    Smith DB, Newlands ES, Rustin GJS et al: Comparison of ondansetron plus dexamethasone as antiemetic prophylaxis during cisplatin-containing chemotherapy. Lancet 1991 (338):487–490PubMedCrossRefGoogle Scholar
  9. 9.
    Herrstedt J, Sigsgaard T, Boesgaard M, Jensen TP, Dombernowsky: Ondansetron plus metopimazine compared with ondansetron alone in patients receiving moderately emetogenic chemotherapy. N Engl J Med 1993 (328): 1076–1080PubMedCrossRefGoogle Scholar
  10. 10.
    Lewith GT, Lewith NR. Modern Chinese Acupuncture. Thorsons Publishers Ltd, Wellingborough 1980Google Scholar
  11. 11.
    Lewith GT, Machin D: On the evaluation of the clinical effects of acupuncture. Pain 1983 (16):111–127PubMedCrossRefGoogle Scholar
  12. 12.
    Chestnutt WN, Dundee JW: Acupuncture for relief of meptanozol-induced vomiting. Br J Anaesth 1985 (57):825P–826PGoogle Scholar
  13. 13.
    Dundee JW, Chestnutt WN, Ghaly RG, Lynas AGA: Traditional Chinese acupuncture: a potentially useful antiemetic? Br Med J 1986 (293):583–584CrossRefGoogle Scholar
  14. 14.
    Dundee JW, Fitzpatrick KTJ, Ghaly RG, Patterson CC: Does dextrality or sinistrality affect the outcome of P6 acupuncture anti-emesis? Br J Clin Pharmacol 1988 (25):679P–680PGoogle Scholar
  15. 15.
    Ghaly RG, Fitzpatrick KTJ, Dundee JW: Antiemetic studies with traditional Chinese acupuncture. A comparison of manual needling with electrical stimulation and commonly used antiemetics. Anaesthesia 1987 (42): 1108–1110PubMedCrossRefGoogle Scholar
  16. 16.
    Fry ENS: Acupressure and postoperative vomiting. Anaesthesia 1986 (41):661–662PubMedCrossRefGoogle Scholar
  17. 17.
    Weightman WM, Zacharias M, Herbison P: Traditional Chinese acupuncture as an antiemetic. Br Med J 1987 (295): 1379–1380CrossRefGoogle Scholar
  18. 18.
    Dundee JW, Milligan KR: Acupuncture as an antiemetic. Br Med J 1988 (296): 135CrossRefGoogle Scholar
  19. 19.
    Fassoulaki A, Papilas K, Sarantopoulos C, Zotou M: Transcutaneous electrical nerve stimulation reduces the incidence of vomiting after hysterectomy. Anesth Analg 1993 (76):1012–1014PubMedCrossRefGoogle Scholar
  20. 20.
    Dundee JW, Ghaly RG, Fitzpatrick KTJ: Randomised comparison of the antiemetic effects of meto-clopramide and electroacupuncture in cancer chemotherapy. Br J Clin Pharmacol 1988 (25):678P–679PGoogle Scholar
  21. 21.
    Moertel CG, Reitemeier RJ: Controlled clinical studies of orally administered antiemetic drugs. Gastroenterology 1969 (57):262–268PubMedGoogle Scholar
  22. 22.
    Morran C, Smith DC, Anderson DA, McArdle CS: Incidence of nausea and vomiting with cytotoxic chemotherapy: a prospective randomised trial of antiemetics. Br Med J 1979 (1): 1323–1324PubMedCrossRefGoogle Scholar
  23. 23.
    Fetting JH, Grochow LB, Folstein MF, Ettinger DS, Colvin M: The course of nausea and vomiting after high-dose cyclophosphamide. Cancer Treat Rep 1982 (66): 1487–1493PubMedGoogle Scholar
  24. 24.
    Dundee JW, Ghaly RH, Fitzpatrick KTJ, Abram WP, Lynch GA: Acupuncture prophylaxis of cancer chemotherapy-induced sickness. J Roy Soc Med 1989(82):268–271PubMedGoogle Scholar
  25. 25.
    Dundee JW, Ghaly RG, Fitzpatrick KTJ, Lynch GA, Abram WP: Acupuncture to prevent cisplatin-associated vomiting. Lancet 1987 (1):1083PubMedCrossRefGoogle Scholar
  26. 26.
    Dundee JW, Yang J: Prolongation of the antiemetic action of P6 acupuncture by acupressure in patients having cancer chemotherapy. J Roy Soc Med 1990 (83):360–362PubMedGoogle Scholar
  27. 27.
    Aglietti L, Roila F, Tonato M et al: A pilot study of metoclopramide, dexamethasone, diphenhydramine and acupuncture in women treated with cisplatin. Cancer Chemother Pharmacol 1990 (26):239–240PubMedCrossRefGoogle Scholar
  28. 28.
    Sailer R, Hellenbrecht D, Bühring M, Hess H: Enhancement of the antiemetic action of metoclopramide against cisplatin-induced emesis by transdermal electrical nerve stimulation. J Clin Pharmacol 1986 (26):115–119Google Scholar
  29. 29.
    Sailer R, Hellenbrecht D, Hellstem A, Hess H: Improved benefit/risk ratio of higher-dose metoclopramide therapy during cisplatin-induced emesis. Eur J Clin Pharmacol 1985 (29):311–312CrossRefGoogle Scholar
  30. 30.
    Redd WH, Andrykowski MA: Behavioral intervention in cancer treatment: controlling aversion reactions to chemotherapy. J Consult Clin Psychol 1982 (50):1018–1029PubMedCrossRefGoogle Scholar
  31. 31.
    Cotanch PH: Relaxation techniques as antiemetic therapy. In: Laszlo J (ed) Antiemetic and Cancer Chemotherapy. Williams & Wilkins, Baltimore/ London 1983 pp 164–176Google Scholar
  32. 32.
    Pratt A, Lazar RM, Penman D, Holland JC: Psychological parameters of chemotherapy-induced conditioned nausea and vomiting: a review. Cancer Nurs 1984(Dec):483–490Google Scholar
  33. 33.
    Morrow GR, Dobkin PL: Anticipatory nausea and vomiting in cancer patients undergoing chemotherapy treatment: prevalence, etiology, and behavioral interventions. Clin Psychol Rev 1988 (8):517–556CrossRefGoogle Scholar
  34. 34.
    Carey MP, Burish TG: Etiology and treatment of the psychological side effects associated with cancer chemotherapy: a critical review and discussion. Psychol Bulletin 1988 (104):307–325CrossRefGoogle Scholar
  35. 35.
    Redd WH, Silberfarb PM, Andersen BL et al: Physiologic and psychobehavioral research in oncology. Cancer 1991 (67):813–822PubMedCrossRefGoogle Scholar
  36. 36.
    Trijsburg RW, Van Knippenberg FCE: Effects of psychological treatment on cancer patients: a critical review. Psychosomatic Medicine 1992 (54):489–517PubMedGoogle Scholar
  37. 37.
    Wilcox PM, Fetting JH, Nettesheim KM, Abeloff MD: Anticipatory vomiting in women receiving cyclophosphamide, methotrexate, and 5-FU (CMF), adjuvant chemotherapy for breast carcinoma. Cancer Treat Rep 1982 (66): 1601–1604PubMedGoogle Scholar
  38. 38.
    Morrow GR: Prevalence and correlates of anticipatory nausea and vomiting during chemotherapy. UNCI 1982 (68):585–588Google Scholar
  39. 39.
    Cohen RE, Blanchard EB, Ruckdeschel JC, Smolen RC: Prevalence and correlates of posttreatment and anticipatory nausea and vomiting in cancer chemotherapy. J Psychosomatic Res 1986 (30): 643–654CrossRefGoogle Scholar
  40. 40.
    Fetting JH, Wilcox PM, Iwata BA et al: Anticipatory nausea and vomiting in an ambulatory medical oncology population. Cancer Treat Rep 1983 (67): 1093–1098PubMedGoogle Scholar
  41. 41.
    Leventhal H, Easterling DV, Nerenz DR, Love RR: The role of motion sickness in predicting anticipatory nausea. J Behav Med 1988 (11):117–130PubMedCrossRefGoogle Scholar
  42. 42.
    Morrow GR: Susceptibility to motion sickness and the development of anticipatory nausea and vomiting in cancer patients. Cancer Treat Rep 1984 (68):99–100Google Scholar
  43. 43.
    Andrykowski MA, Redd WH: Development of anticipatory nausea: a prospective analysis. J Consult Clin Psychol 1985 (53):447–454PubMedCrossRefGoogle Scholar
  44. 44.
    Andrykowski MA, Jacobsen PB, Marks E et al: Prevalence, predictors, and course of anticipatory nausea in women receiving adjuvant chemotherapy for breast cancer. Cancer 1988 (62):2607–2613PubMedCrossRefGoogle Scholar
  45. 45.
    Bovbjerg DH, Redd WH, Jacobson PB et al: An experimental analysis of classically conditioned nausea during cancer chemotherapy. Psychosomatic Med 1992 (54):623–637Google Scholar
  46. 46.
    Burish TG, Carey MP: Conditioned aversive responses in cancer chemotherapy patients: theoretical and developmental analysis. J Consult Clin Psychol 1986 (54):593–600PubMedCrossRefGoogle Scholar
  47. 47.
    Dahlquist LM, Gil KM, Armstrong FD, Ginsberg FD, Jones B: Behavioral management of children’s distress during chemotherapy. J Behav Ther Exp Psychiatry 1985 (16):325–329PubMedCrossRefGoogle Scholar
  48. 48.
    Burish TG, Shartner CD, Lyles JN: Effectiveness of multiple-site EMG biofeedback and relaxation in reducing the aversiveness of cancer chemotherapy. Biofeedback and Seifregulation 1981 (6):523–535CrossRefGoogle Scholar
  49. 49.
    Burish TG, Lyles JN: Effectiveness of relaxation training in reducing the aversiveness of chemotherapy in the treatment of cancer. J Behav Ther Exp Psychiatry 1979 (10):357–361CrossRefGoogle Scholar
  50. 50.
    Dempster CR, Balson P, Whalen BT: Supportive hypnotherapy during the radical treatment of malignancies. Int J Clin Exp Hypnosis 1976 (24):1–9CrossRefGoogle Scholar
  51. 51.
    LaClave LJ, Blix S: Hypnosis in the management of symptoms in a young girl with malignant astrocytoma: a challenge to the therapist. Int J Clin Exp Hypnosis 1989 (37):6–14CrossRefGoogle Scholar
  52. 52.
    Kaye JM: Use of hypnosis in the treatment of cancer patients. J Psychosoc Oncology 1987 (5): 11–22CrossRefGoogle Scholar
  53. 53.
    Booraem CD, Flowers JV, Gumbiner J: Combined medical and psychological treatment of postchemo-therapy nausea and vomiting: a case study. Psychological Rep 1989 (65): 187–193CrossRefGoogle Scholar
  54. 54.
    Greene PG, Seime RJ: Stimulus control of anticipatory nausea in cancer chemotherapy. J Behav Ther Exp Psychiatry 1987 (18):61–64PubMedCrossRefGoogle Scholar
  55. 55.
    Olness K: Imagery (self-hypnosis) as adjunct therapy in childhood cancer. Am J Pediatric Hematol-ogy/Oncology 1981 (3):313–321Google Scholar
  56. 56.
    Hockenberry MJ, Cotanch PH: Hypnosis as adjuvant antiemetic therapy in childhood cancer. Nurs Clin North Am 1985 (20):105–107PubMedGoogle Scholar
  57. 57.
    Zeltzer L, Kellerman J, Ellenberg L, Dash J: Hypnosis for reduction of vomiting associated with chemotherapy and disease in adolescents with cancer. J Adolescent Health Care 1983 (4):77–84CrossRefGoogle Scholar
  58. 58.
    LeBaron S, Zeltzer L: Behavioral intervention for reducing chemotherapy-related nausea and vomiting in adolescents with cancer. J Adolescent Health Care 1984 (5):178–182CrossRefGoogle Scholar
  59. 59.
    Zeltzer L, LeBaron S, Zeltzer PM: The effectiveness of behavioral intervention for reduction of nausea and vomiting in children and adolescents receiving chemotherapy. J Clin Oncol 1984 (2):683–690PubMedGoogle Scholar
  60. 60.
    Zeltzer L, Dolgin MJ, LeBaron S, LeBaron C: A randomised, controlled study of behavioral intervention for chemotherapy distress in children with cancer. Pediatrics 1991 (88):34–42PubMedGoogle Scholar
  61. 61.
    Cotanch P, Hockenberry M, Herman S: Self-hypnosis as an antiemetic therapy in children receiving chemotherapy. Oncol Nurs Forum 1985 (12):41–46.PubMedGoogle Scholar
  62. 62.
    Redd WH, Andresen GV, Minagawa RY: Hypnotic control of anticipatory emesis in patients receiving cancer chemotherapy. J Consult Clin Psychology 1982 (50): 14–19CrossRefGoogle Scholar
  63. 63.
    Syrjala KL, Cummings C, Donaldson GW: Hypnosis or cognitive behavioral training for reduction of pain and nausea during cancer treatment: a controlled clinical trial. Pain 1992 (48): 137–146PubMedCrossRefGoogle Scholar
  64. 64.
    Burish TG, Lyles JN: Effectiveness of relaxation training in reducing adverse reactions to cancer chemotherapy. J Behav Med 1981 (4):65–78PubMedCrossRefGoogle Scholar
  65. 65.
    Lyles JN, Burish TG, Krozely MG, Oldham RK: Efficacy of relaxation training and guided imagery in reducing the aversiveness of cancer chemotherapy. J Consult Clin Psychology 1982 (50):509–524CrossRefGoogle Scholar
  66. 66.
    Burish TG, Carey MP, Krozely MG, Greco FA: Conditioned side effects induced by cancer chemotherapy: prevention through behavioral treatment. J Consult Clin Psychology 1987 (55):42–48CrossRefGoogle Scholar
  67. 67.
    Carey MP, Burish TG: Providing relaxation training to cancer chemotherapy patients: a comparison of three delivery techniques. J Consult Clin Psychology 1987 (55): 732–737CrossRefGoogle Scholar
  68. 68.
    Cotanch PH: Relaxation training for control of nausea and vomiting in patients receiving chemotherapy. Cancer Nurs 1983 (6):277–283PubMedCrossRefGoogle Scholar
  69. 69.
    Cotanch PH, Strum S: Progressive muscle relaxation as antiemetic therapy for cancer patients. Oncol Nurs Forum 1987 (14):33–37PubMedGoogle Scholar
  70. 70.
    Scott DW, Donahue DC, Mastrovito RC, Hakes TB: Comparative trial of clinical relaxation and an antiemetic drug regimen in reducing chemotherapy-related nausea and vomiting. Cancer Nurs 1986 (9): 178–187CrossRefGoogle Scholar
  71. 71.
    Gralla RJ, Itri LM, Pisko SE et al: Antiemetic efficacy of high-dose metoclopramide: randomized trials with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting. N Engl J Med 1981 (305):905–909PubMedCrossRefGoogle Scholar
  72. 72.
    Holli K: Ineffectiveness of relaxation on vomiting induced by cancer chemotherapy. Eur J Cancer 1993 (29A): 1915–1916PubMedCrossRefGoogle Scholar
  73. 73.
    Wolpe J: The Practice of Behavior Therapy (3rd ed). Pergamon Press, Oxford 1983Google Scholar
  74. 74.
    Reesal RT, Bajramovic H, Mai F: Anticipatory nausea and vomiting: a form of chemotherapy phobia? Can J Psychiatry 1990 (35):80–82PubMedGoogle Scholar
  75. 75.
    Hailey BJ, White JG: Systematic desensitization for anticipatory nausea associated with chemotherapy. Psychosomatic 1983 (24):289–291Google Scholar
  76. 76.
    Hoffman ML: Hypnotic desensitization for the management of anticipatory emesis in chemotherapy. Am J Clin Hypnosis 1982–1983 (25):173–176CrossRefGoogle Scholar
  77. 77.
    Morrow GR, Morrell C: Behavioral treatment for the anticipatory nausea and vomiting induced by cancer chemotherapy. N Engl J Med 1982 (307): 1476–1480PubMedCrossRefGoogle Scholar
  78. 78.
    Morrow GR: Effect of the cognitive hierarchy in the systematic desensitization treatment of anticipatory nausea in cancer patients: a component comparison with relaxation only, counseling, and no treatment. Cogn Ther Res 1986 (10):421–446CrossRefGoogle Scholar
  79. 79.
    Shartner CD, Burish TG, Carey MP: Effectiveness of biofeedback with progressive muscle relaxation training in reducing the aversiveness of cancer chemotherapy: a preliminary report. Jap J Biofeedback Res 1985 (12):33–40Google Scholar
  80. 80.
    Nerenz DR, Leventhal H, Easterling DV, Love RR: Anxiety and taste as predictors of anticipatory nausea in cancer chemotherapy. J Clin Oncol 1986 (4):224–233PubMedGoogle Scholar
  81. 81.
    Moore K, Altmaier EM: Stress inoculation training with cancer patients. Cancer Nurs 1981 (Oct):389–393Google Scholar
  82. 82.
    Frank JM: The effects of music therapy and guided visual imagery on chemotherapy induced nausea and vomiting. Oncology Nursing Forum 1985 (12):47–52PubMedGoogle Scholar
  83. 83.
    Porchet-Munro S: Music therapy in support of cancer patients. In: Senn HJ, Glaus A, Schmid L (eds) Recent Results in Cancer Research: Supportive Care in Cancer Patients. Springer-Verlag, Berlin 1988 pp 289–294Google Scholar
  84. 84.
    Kolko DJ, Rickard-Figueroa JL: Effects of video games on the adverse corollaries of chemotherapy in pediatric oncology patients: a single-case analysis. J Consult Clin Psychology 1985 (53):223–228CrossRefGoogle Scholar
  85. 85.
    Redd WH, Jacobsen PB, Die-Trill M et al: Cognitive/attentional distraction in the control of conditioned nausea in pediatric cancer patients receiving chemotherapy. J Consult Clin Psychology 1987 (55):391–395CrossRefGoogle Scholar
  86. 86.
    Friedlander M, Kearsley JH, Tattersall MHN: Oral lorazepam to improve tolerance of cytotoxic therapy. Lancet 1981 (1):1316–1317PubMedCrossRefGoogle Scholar
  87. 87.
    Bishop JF, Olver IN, Wolf MM et al.: Lorazepam: a randomized, double-blind, crossover study of a new antiemetic in patients receiving cytotoxic chemotherapy and prochlorperazine. J Clin Oncol 1984 (2):691–695PubMedGoogle Scholar
  88. 88.
    Razavi D, Delvaux N, Farvacques C et al.: Prevention of adjustment disorders and anticipatory nausea secondary to adjuvant chemotherapy: a double-blind, placebo-controlled study assessing the usefulness of alprazolam. J Clin Oncol 1993 (11):1384–1390PubMedGoogle Scholar
  89. 89.
    Stefanik ME, Sheidler VR, Fetting JH: Anticipatory nausea and vomiting: does it remain a significant problem? Cancer 1988 (62):2654–2657CrossRefGoogle Scholar
  90. 90.
    Grunberg SM, Hesketh PJ: Control of chemotherapy-induced emesis. N Engl J Med 1993 (329): 1790–1796)PubMedCrossRefGoogle Scholar
  91. 91.
    Soukop M, McQuade B, Hunter E et al.: Ondansetron compared with metoclopramide in the control of emesis and quality of life during repeated chemotherapy for breast cancer. Oncology 1992 (49):295–304PubMedCrossRefGoogle Scholar
  92. 92.
    Watson M: Anticipatory nausea and vomiting: broadening the scope of psychological treatments. Support Care Cancer 1993 (1): 171–177PubMedCrossRefGoogle Scholar
  93. 93.
    Redd WH: Advances in behavioural intervention in comprehensive cancer treatment. Support Care Cancer 1994 (2):111–115PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • Jørn Herrstedt
    • 1
  1. 1.Department of Medicine/Medical Oncology FHillerød HospitalHillerødDenmark

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