Septic Shock: Cardiovascular Function and Management
Septic shock is one of the most common causes of morbidity and mortality in patients in intensive care units. Despite the great advances in antibiotic therapy over the past two decades, the mortality from septic shock has not decreased appreciably. Our understanding of the pathophysiology of sepsis and septic shock has evolved rapidly over this time. As we understand the pathophysiology of the syndrome better, our treatment of patients will become more focussed and, we hope, more effective. The acute event that brings the patient to the intensive care unit is often the development of shock. This article will discuss the changes in cardiovascular function that occur in the patient with septic shock and the current approaches to hemodynamic management.
KeywordsSeptic Shock Cardiac Index Oxygen Delivery Systemic Vascular Resistance Pulmonary Artery Occlusion Pressure
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