Clinical Markers of Gastrointestinal Dysfunction

  • J. C. Marshall
Part of the Update in Intensive Care and Emergency Medicine book series (UICM, volume 26)


Physiologic support of failing vital organ function is the “raison d’être” of the intensive care unit (ICU). The development of individual organ dysfunction in the critically ill patient describes a clinical syndrome and defines a series of therapeutic challenges. The challenge of pulmonary failure, manifested as the acute respiratory distress syndrome (ARDS), is to support optimal gas exchange without inducing further iatrogenic lung injury, while that of acute renal failure is to optimize fluid and electrolyte homeostasis without adversely affecting systemic hemodynamic function. In aggregate, graded degrees of vital organ dysfunction comprise the multiple organ dysfunction syndrome (MODS), the leading cause of ICU morbidity and mortality, and the embodiment of the unsolved obstacles to recovery from critical illness [14].


Critical Illness Multiple Organ Dysfunction Syndrome Acalculous Cholecystitis Stress Ulcer Prophylaxis Gastrointestinal Dysfunction 
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© Springer-Verlag Berlin Heidelberg 1996

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  • J. C. Marshall

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