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Mast Cells and Neutrophils in Intestinal Ischemia/Reperfusion

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Gut Dysfunction in Critical Illness

Part of the book series: Update in Intensive Care and Emergency Medicine ((UICM,volume 26))

Abstract

The key features of reperfusion of ischemic intestine associated with hemorrhage and other shock states include microvascular and mucosal alterations such as endothelial cell swelling, capillary plugging, a prolonged reduction in intestinal blood flow and mucosal barrier dysfunction [1–3]. The intestinal lesion becomes a very important factor inasmuch as loss of a restrictive lumenal barrier is strongly associated with toxic factors entering the circulation and causing sepsis and possibly multiple organ failure in patients otherwise recovering from shock [2].

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Authors
  1. P. Kubes
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Editor information

Editors and Affiliations

  1. Department of Surgery, Pennsylvania University Hospital, 3400 Spruce Street, 19104, Philadelphia, PA, USA

    J. L. Rombeau

  2. Department of Intensive Care Critical Care Research Program, Kuopio University Hospital, FIN-70211, Kuopio, Finland

    J. Takala

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© 1996 Springer-Verlag Berlin Heidelberg

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Kubes, P. (1996). Mast Cells and Neutrophils in Intestinal Ischemia/Reperfusion. In: Rombeau, J.L., Takala, J. (eds) Gut Dysfunction in Critical Illness. Update in Intensive Care and Emergency Medicine, vol 26. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80224-9_7

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  • DOI: https://doi.org/10.1007/978-3-642-80224-9_7

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80226-3

  • Online ISBN: 978-3-642-80224-9

  • eBook Packages: Springer Book Archive

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