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Pharmacodynamics and Pharmacokinetics of Acamprosate: An Overview

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Acamprosate in Relapse Prevention of Alcoholism

Abstract

Acamprosate (calcium acetylaminopropane sulphonate) is the active substance of Campral and has the following chemical structure (CH3-CO-NH-CH2-CH2CH2-S03)2Ca. The molecular structure is related to biologically active amino acids such as:

  • Taurine (NH2-CH2-CH2-SO3H),

  • Gamma-aminobutyric acid (GABA), (NH-CH2-CH2-CH2-COOH),

  • Glutamic acid NH2-CHCOOH-CH2-CH2-COOH.

Most data presented in this paper are part of the acamprosate European registration dossier.

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Authors and Affiliations

  1. Research and Development Centre, Groupe LIPHA, 115 avenue Lacassagne, 69003, Lyon, France

    P. Durbin, T. Hulot & S. Chabac

Authors
  1. P. Durbin
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  2. T. Hulot
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  3. S. Chabac
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Editor information

Editors and Affiliations

  1. Psychiatrische Klinik und Poliklinik, Universität München, Nußbaumstr. 7, 80336, München, Germany

    Michael Soyka

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© 1996 Springer-Verlag Berlin Heidelberg

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Durbin, P., Hulot, T., Chabac, S. (1996). Pharmacodynamics and Pharmacokinetics of Acamprosate: An Overview. In: Soyka, M. (eds) Acamprosate in Relapse Prevention of Alcoholism. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80193-8_3

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  • DOI: https://doi.org/10.1007/978-3-642-80193-8_3

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-80195-2

  • Online ISBN: 978-3-642-80193-8

  • eBook Packages: Springer Book Archive

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