Pharmacodynamics and Pharmacokinetics of Acamprosate: An Overview

  • P. Durbin
  • T. Hulot
  • S. Chabac


Acamprosate (calcium acetylaminopropane sulphonate) is the active substance of Campral and has the following chemical structure (CH3-CO-NH-CH2-CH2CH2-S03)2Ca. The molecular structure is related to biologically active amino acids such as:
  • Taurine (NH2-CH2-CH2-SO3H),

  • Gamma-aminobutyric acid (GABA), (NH-CH2-CH2-CH2-COOH),

  • Glutamic acid NH2-CHCOOH-CH2-CH2-COOH.


Alcohol Dependence Excitatory Amino Acid Alcohol Withdrawal Gaba Uptake Alcohol Alcohol 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • P. Durbin
    • 1
  • T. Hulot
    • 1
  • S. Chabac
    • 1
  1. 1.Research and Development CentreGroupe LIPHALyonFrance

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