Pharmacodynamics and Pharmacokinetics of Acamprosate: An Overview

  • P. Durbin
  • T. Hulot
  • S. Chabac
Conference paper


Acamprosate (calcium acetylaminopropane sulphonate) is the active substance of Campral and has the following chemical structure (CH3-CO-NH-CH2-CH2CH2-S03)2Ca. The molecular structure is related to biologically active amino acids such as:
  • Taurine (NH2-CH2-CH2-SO3H),

  • Gamma-aminobutyric acid (GABA), (NH-CH2-CH2-CH2-COOH),

  • Glutamic acid NH2-CHCOOH-CH2-CH2-COOH.


Nicotinate NMDA Diazepam Taurine Valproate 


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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • P. Durbin
    • 1
  • T. Hulot
    • 1
  • S. Chabac
    • 1
  1. 1.Research and Development CentreGroupe LIPHALyonFrance

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