Intralabyrinthine pressure transmission of intracranial pressure in the normal guinea pig

  • J. C. Andrews
  • D. Strelioff


Although basic for understanding normal inner ear function, our knowledge of intralabyrinthine fluid and pressure dynamics is only fundamental and remains largely theoretical. Sound is a pressure variation of a magnitude less than the steady state pressure maintained within the inner ear. The intralabyrinthine fluid movement that occurs within the inner ear secondary to a sound stimulus will be dependent on the intrinsic pressures within the fluids. Similarly with rotational vestibular stimulation; fluid movement within the inner ear occurs and is dependent on inner ear pressure. To further confound the issue, it is likely that the inner ear pressure is dynamic and constantly changing with activity (Andrews et al 1991). Yet the inner ear is able to instantaneously adapt providing a stable baseline for receiving an auditory or vestibular stimulus without distortion. The mechanism for fluid and pressure regulation is likely complex with a number of possibilities for error leading to inner ear disorders such as Meniere’s disease.


Intracranial Pressure Internal Auditory Canal Endocochlear Potential Pressure Transmission Round Window Membrane 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • J. C. Andrews
    • 1
  • D. Strelioff
    • 1
  1. 1.Division of Head and Neck SurgeryUCLA Medical CenterUSA

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