Abstract
Up till now, little is known about the need and the effect of analgesics in newborns and infants in the postoperative period. Insufficient analgesia can give rise to stress responses with an increased morbidity, while high doses of opioids will give a deep sedation with a possible need for prolonged artificial ventilation. Adequate analgesia can only be reached when the concentration of the analgesic drug lies within the analgesic corridor, meaning between the minimal effective plasma concentration and the toxic concentration. The minimal effective analgesic plasma concentration however can be different from person to person.
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© 1996 Springer-Verlag Berlin Heidelberg
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Bouwmeester, J., Passchier, J., Tibboel, D. (1996). Pain Measurement in Children. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 1996. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80053-5_61
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DOI: https://doi.org/10.1007/978-3-642-80053-5_61
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