Abstract
Despite notable successes in many areas of critical care medicine, the reported mortality rate of the acute respiratory distress syndrome (ARDS) has arguably failed to decline from 50–70%, since its original description in 1967. There remains no proven treatment that directly reverses the underlying pathology in ARDS, therefore management is primarily supportive, of which mechanical ventilation remains the mainstay. Recently, it has been recognized that mechanical ventilation, though life-sustaining, may aggravate or even initiate ARDS through ventilator-induced lung injury (VILI). This realization has necessitated a re-evaluation of ventilatory strategies. Thus, ventilatory strategies, that attempt to limit VILI and potentially accept permissive hypercapnia, are becoming more acceptable and appear to decrease mortality in uncontrolled settings [1, 2]. This clinical work, supported by animal studies, has led to a shift in the philosophy of mechanical ventilation in ARDS. Lung protection is now at the fore, while maintenance of “normal” physiologic parameters has become a secondary objective. Though, data on patient positioning, particularly prone positioning, has been available for years, it is only recently becoming generally appreciated that this position may augment the use of lung protective ventilatory strategies (LPVS) in ARDS.
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Kirkpatrick, A.W., Meade, M.O., Stewart, T.E. (1996). Lung Protective Ventilatory Strategies in ARDS. In: Vincent, JL. (eds) Yearbook of Intensive Care and Emergency Medicine. Yearbook of Intensive Care and Emergency Medicine, vol 1996. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-80053-5_35
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DOI: https://doi.org/10.1007/978-3-642-80053-5_35
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