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Strategies to minimize Alveolar Stretch Injury during Mechanical Ventilation

  • N. R. MacIntyre
Part of the Yearbook of Intensive Care and Emergency Medicine book series (YEARBOOK, volume 1996)

Abstract

The potential for positive pressure breaths to injure the lungs has long been appreciated. The best known form of injury occurs when positive pressure breaths grossly overinflate the lungs and result in pneumothorax, pneumomediastinum, subcutaneous emphysema, and other forms of “volutrauma” or “barotrauma” [1–4]. The mechanism for this type of injury is thought to be actual alveolar rupture into the perivascular space with subsequent dissection of air into the mediastinum, pleura and other locations [3–5]. The risk for alveolar overdistension and rupture becomes clinically significant when transalveolar pressures exceed the normal maximum and approach 50–60 cm H2O (Fig. 1).

Keywords

Tidal Volume Acute Lung Injury Acute Respiratory Distress Syndrome Respir Crit High Frequency Oscillatory Ventilation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • N. R. MacIntyre

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